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    Effect of Copper Addition to Aluminium Alloys on Surface Roughness in Terms of Turning Operation
    (Polish Acad Sciences Inst Physics, 2017) Ozen, F.; Ficici, F.; Dundar, M.; Colak, M.
    Aluminium alloys have found usage in numerous industries due to some superior properties, such as high strength-to-weight ratios and high oxidation resistance. Aluminum alloys can be strengthened by some techniques. One of them, the most practical one, is precipitation hardening in aluminum alloys. By adding Cu, aluminum gains strength and hardness. In this work the machinability of unalloyed aluminum and aluminum alloyed with 4% and 8% of Cu have been investigated. Machinability assessment was executed in terms of surface roughness during turning operation. Specimens were manufactured by sand casting method, which is a commonly utilized casting operation. In machinability experiments, three different cutting tool materials were employed. Three different cutting speeds and three different feed rates have been used. Effect of these feeds, speeds and cutting tool materials on surface roughness has been studied. In addition, effect of Cu addition to aluminum alloys on surface roughness has been examined.
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    Investigation of the Delamination Factor of Glass Sphere and Silicon Particle Reinforced (GS-SCR) Hybrid Composite Material
    (Polish Acad Sciences Inst Physics, 2017) Dundar, M.; Ficici, F.; Ozen, F.; Unal, H.
    Reinforced polymer composite materials have opened a new era because they can substitute the conventional metallic materials. These materials have found numerous usage areas, especially in aviation, military and space applications due to such advantages as the high tensile strength, high modulus, high corrosion resistance and low density. However, during the assembly of parts from these materials, a huge amount of holes is required. There are problems during machining of reinforced polymer composite materials. Main reason behind these problems is the inhomogeneous microstructure. Some of these problems are burr, pullout, swelling, microcrack, rapid tool wear and delamination. Among the most important of these defects is the delamination damage. Delamination is a severe drilling failure. In this work, three different cutting speeds (15, 20, 25 m/min), three different feed rates (0.05, 0.10, 0.15 mm/rev) and three different cutting tool materials (Carbide, TiN Coated HSS and HSS) have been used. Effect of different feed rates, cutting speeds and tool materials on delamination is studied by drilling of % 10 glass sphere- and % 10 silicon particle-reinforced polypropylene hybrid composite material.
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    Öğe
    The prevalence of Familial Mediterranean Fever common gene mutations in patients with simple febrile seizures
    (Verduci Publisher, 2014) Ozen, F.; Kocak, N.; Kelekci, S.; Yildirim, I. H.; Hacimuto, G.; Ozdemir, O.
    BACKGROUND: Febrile seizures (FS) represent the most common form of childhood seizures that occurs in 2-5 % of the children younger than 6 years. There have been many recent reports on the molecular genetic and pathogenesis of FC. It has been recognized that there is significant genetic component for susceptibility of FC with different reported mutation. FEB1, FEB2, FEB4, SCNA1, SCNA2, GABRG2 and IL-1 beta are related to with febrile convulsions (FCs). Interleukin 1 beta (IL-1 beta) is a cytokine that contributes to febrile inflammatory responses. There are conflicting results on increasing this cytokine in serum during FC. AIM: The determine the association between mutations of MEFV gene product pyrine and febrile seizures. PATIENTS AND METHODS: The study was carried out on 104 children that were diagnosed as FS and 96 healthy children. MEFV gene mutations were detected and analyzed with Pyro-Mark Q24. PCR was performed using the Pyro-Mark PCR Kit and pyrosequencing reaction was conducted on instrument instructions. RESULTS: M694V is the most common mutation in our patient group and we found a significant association between MEFV gene mutations and FSs. Of 104 patients, 68 were heterozygotes for any mutation and 10 patients were compound. 17.7% of control group were heterozygotes for any studied mutation. Statistical analyses showed that there was strongly significant statistical difference between results obtained from FS and control group (X = 46.20, p < 0.0001). CONCLUSIONS: MEFV gene mutations, especially M694V mutation, are positively associated with FSs.