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    A Case of Oxcarbazepine-Induced Severe Hyponatremia
    (Kare Publ, 2011) Degirmenci, Yildiz; Yilmaz, Yeliz; Ors, Ceyda Hayretdag; Karaman, Handan Isin Ozisik
    Oxcarbazepine is a keto-analogue of carbamazepine. Hyponatremia seen in the patients treated with oxcarbazepine is usually asymptomatic and rarely severe which leads to drug withdrawal. Here we presented a 51-year old female patient with epilepsy under oxcarbazepine and valproate treatment, who presented to our outpatient neurology clinic with vertigo, nausea and vomitting after the usage of her antiepileptic drugs. Routine biochemistry evluations revealed a decresed serum sodium level with increased urine sodium and osmolarity levels. Renal ultrasonography was normal. The patient was pre-diagnosed as inappropriate antidiuretic hormone secretion syndrome. Three days after the oxcarbazepine withdrawal, serum and urine sodium levels were found to be normal.
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    Case of Cytomegalovirus Infection Causing Isolated Oculomotor Nerve Palsy
    (Derman Medical Publ, 2014) Sen, Halil Murat; Tosum, Yeliz Yilmaz; Ors, Ceyda Hayretdag; Karaman, Handan Isin Ozisik
    The third cranial nerve is called the oculomotor nerve. The pathology is revealed by limitation of eye movement inward-up-down, mydriasis, loss of light reflex and ptosis. Oculomotor nerve pathologies are frequently seen in neurology practice and are situations that may be very difficult for differential diagnosis. Differential diagnosis first involves disqualifying intracranial etiologies by imaging because these intracranial etiologies may be situations that can result in death and should be primarily evaluated. If intracranial events are ruled out, generally rarer etiologic reasons with generally difficult differentiation should be researched. Viral infections are among the rare etiological reasons causing 3rd cranial nerve involvement. Our case was a 71-year old female with etiological research due to 3rd cranial nerve palsy. The patient with diabetes-linked immune deficiency was found to have cranial nerve involvement developed secondary to cytomegalovirus (CMV) infection. We report this case as 3rd cranial nerve involvement is rarely observed developing linked to CMV infection.
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    Investigation of auditory potentials and cognitive impairment in premenstrual syndrome
    (Springer-Verlag Italia Srl, 2018) Ors, Ceyda Hayretdag; Karaman, Handan Isin Ozisik
    Premenstrual syndrome is a term which is used for describing of somatic, cognitive, emotional, and behavioral symptoms that occur during the luteal phase of menstrual cycle in women of reproductive age; symptoms rapidly improve at the onset of menstruation. In this study, we aimed to reveal if cognitive functions are affected or not in PMS and if the subjects are affected, we try to explain this situation by an objective diagnostic test. Ethical committee approval was taken for this project on 09.03.2012 and numbered 050.99-60. In this study, in order to determine premenstrual syndrome, Premenstrual Syndrome Scale that is developed by Gen double dagger dogan (2006) with 44 items, Likert type, and 9 subgroups was used. Sample size was calculated using simple random sampling with a confidence level of 95% and confidence interval of 0.05. A total of 60 participants were included in the study (calculated sample size was 30 for each group). Each group was recorded in the ENMG-UP laboratory using the OIP auditory warning and the oddball two-tone discrimination task method. Latency measurements were taken from the highest point of the peak, and amplitude measurements were taken from peak to peak with a cursor. Comparisons of P300 wave latencies obtained via sparse auditory stimulus in PMS and non-PMS groups were made and findings were summarized in one of the tables. Recordings are taken from three scalp regions: parietal and central, respectively. PMS women have longer P300 wave latencies in all regions compared to non-PMS group, whereas there is no significant difference between P300 amplitude.
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    Isolated lingual dystonia induced by speaking: a rare form of focal dystonia
    (Acta Medica Belgica, 2011) Degirmenci, Yildiz; Ors, Ceyda Hayretdag; Yilmaz, Yeliz; Karaman, Handan Isin Ozisik
    Focal lingual dystonia is a rare condition that can be misdiagnosed as a psychogenic problem because it may interfere with chewing, swallowing, and speaking. We present a patient with an uncommon type of dystonia (speech-induced primary lingual dystonia), that responded well to botulinum toxin injection.
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    Melkersson-Rosenthal Syndrome in a Patient with Systemic Lupus Erythematosus: A Rare Comorbidity
    (Turkish League Against Rheumatism, 2012) Degirmenci, Yildiz; Kobak, Senol; Ors, Ceyda Hayretdag; Karaman, Handan Ozisik
    Melkersson-Rosenthal syndrome (MRS) is a rare granulomatous disease characterized by recurrent orofacial edema, facial palsy, and a fissured tongue. In this article, we report a 23-year-old female case with recurrent peripheral facial palsy, mild orofacial edema, and a fissured tongue. She had spots in her feet with a history of oral aphthous ulcers and experienced a relapse once a year. The neuroimaging results were normal, however the laboratory examination indicated systemic lupus erythematosus (SLE). This rare case is presented to emphasize the complete triad of MRS concomitantly occurring with SLE in this patient.
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    Parotid Abscess with Involvement of Facial Nerve Branches
    (Coll Physicians & Surgeons Pakistan, 2015) Ozkan, Adile; Ors, Ceyda Hayretdag; Kosar, Sule; Karaman, Handan Isin Ozisik
    Facial nerve paresis is only rarely seen with benign diseases of the parotid gland. A 22-year male had muscle loss in the preauricular region of the right side of his face that extended towards the mandibular angle for the last 6 months. The neurological examination did not reveal any pathology other than right preauricular region muscle atrophy that was limited by the mandibular angle. The Electroneuronography (EnoG) provided a ratio of 55.38%, compared the affected side to left side. Ultrasonography of the defined region showed two mass lesions 13.5 x 7 mm and 10 x 5 mm in size in the anteromedial section of the right parotid gland that were close to each other, without internal calcific foci, and heterogenous hyperechogenic structure without internal vascularization. Fine needle aspiration obtained many polymorphonuclear leukocytes, cell debris, a few mononuclear inflammatory cells and many crystalloid structures: The lesion was diagnosed as a parotid abscess. Antibiotic treatment was started for the parotid gland abscess.
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    Parotid abscess with involvement of facial nerve branches
    (College of Physicians and Surgeons Pakistan, 2015) Ozkan, Adile; Ors, Ceyda Hayretdag; Kosar, Sule; Karaman, Handan Isin Ozisik
    Facial nerve paresis is only rarely seen with benign diseases of the parotid gland. A 22-year male had muscle loss in the preauricular region of the right side of his face that extended towards the mandibular angle for the last 6 months. The neurological examination did not reveal any pathology other than right preauricular region muscle atrophy that was limited by the mandibular angle. The Electroneuronography (EnoG) provided a ratio of 55.38%, compared the affected side to left side. Ultrasonography of the defined region showed two mass lesions 13.5 x 7 mm and 10 x 5 mm in size in the anteromedial section of the right parotid gland that were close to each other, without internal calcific foci, and heterogenous hyperechogenic structure without internal vascularization. Fine needle aspiration obtained many polymorphonuclear leukocytes, cell debris, a few mononuclear inflammatory cells and many crystalloid structures. The lesion was diagnosed as a parotid abscess. Antibiotic treatment was started for the parotid gland abscess.