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Öğe Bioprocess monitoring by biosensor-based technologies(Elsevier, 2020) Goker, Meric; Kurbanoglu, Sevinc; Huri, Pinar Yilgor; Sezgintürk, Mustafa Kemal; Ozkan, Sibel A.Today, biotechnological process applications are frequently used by an increasing importance in terms of industry and research. One of the natural consequences of scientific advances is the provision of more rapid progression by the effects on several scientific fields. Therefore, the rapid introduction of biotechnological processes into our daily lives leads to the development of new experimental tools (imaging methods and metabolic engineering), universal methods of analysis (genomics, proteomics, and metabolomics), and bioinformatics, which are able to respond rapidly to the needs and become more responsive. In this chapter, it is tried to define the bioprocess monitoring and analytical methods for bioprocesses with their measurement principles. Moreover, biologically varying sensors that are used in biomass monitoring and biomass concentration analysis are also defined. Turbidity sensors and impedance sensors, cell morphology analysis, in situ microscope systems, metabolic activity analysis, etc., are also stated. Current challenges with some novel examples are also shared. © 2020 Elsevier Inc. All rights reserved.
