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    Assessment of Pupil Diameters of Emmetropes and Myopes under Photopic, Mesopic and Scotopic Conditions, Using the Infrared Pupillometer Integrated Within Schwind Sirius Multifunctional Diagnostic Device
    (Ortadogu Ad Pres & Publ Co, 2012) Taskiran Comez, Arzu; Komur, Baris; Eser, Ilker
    Objective: To assess the pupil diameters of emmetropes and myopes in photopic, mesopic and scotopic conditions. Material and Methods: Pupil diameters of 49 emmetropic subjects [spherical equivalent (SE) values +/- 0.25 diopter (D) with a mean age of 31.0 +/- 10.5 years (range 17 to 58 years)], and 61 age-matched (mean age 31.3 +/- 8.9 years, range 17 to 52 years) myopic subjects (SE values >=-1D) were measured with the infrared pupillometer integrated within Schwind Sirius Multifunctional diagnostic device (Eye-tech-solutions, Kleinostheim, Germany) in photopic (40 lux) condition simulating the day-time in mesopic (4 lux) condition and in scotopic (0.04 lux) condition simulating the level of light encountered at night. All statistical analyses were performed according to two-sided hypothesis tests and a p-value of less than 0.05 was considered statistically significant. Results: The mean photopic pupil diameter was 3.62 +/- 0.73 mm (range 2.49 to 5.83) in the emmetropic group and 3.86 +/- 0.85 mm (range 2.06 to 6.67) in the myopic group. The mean mesopic pupil diameters were 4.68 +/- 0.78 mm (range 3.19 to 6.45) and 5.16 +/- 0.91 mm (range 3.23 to 7.46) and the mean scotopic pupil diameters were 5.63 +/- 0.70 mm (range 4.28 to 7.14) and 6.08 +/- 0.86 mm (range 4.30 to 7.95) in emmetropes and myopes, respectively. The mean pupil diameters of myopes were larger than emmetropes in all three light conditions (p<0.001). There was no interaction between patient group and light condition (p>0.05). Conclusion: The mean pupil diameters of myopic subjects were larger than the pupil diameter of emmetropes. Pupil diameter should be measured objectively under standardized illumination levels in order to minimize the risk of post-operative glare and halo formation in refractive surgery patients.
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    Is Normative Database of Optical Coherence Tomography Device Comprise Turkish Population
    (Turkish Ophthalmological Soc, 2009) Eser, Ilker; Komur, Baris; Comez, Arzu Taskiran
    Purpose: To compare the retinal nerve fiber layer (RNFL) thickness normative values measured by Optical Coherence Tomography(OCT) with healthy subjects. Methods: Thirty-nine randomized right or left eyes of 39 healthy subjects(18 female, 21 male), with a mean age of 25.1 +/- 3.0(19-29) years were included in the study. Subjects without family history of glaucoma and who were evaluated by intraocular pressure(IOP) measurements, central corneal thickness(CCT), cup/disc ratio and OCT measurement results, and who were accepted as not in risky group for glaucoma were included in the study. Three sequential measurements were taken by Spectral OCT/SLO [Opko/OTI, Inc., Miami, FL] analyzer, by the same operator in the same day, and mean of these 3 measurements was used for the analysis. One sample t-test was used for statistical analysis. Results: The mean values of the subjects and the normative RNFL thickness database used by the device were; 142.5 +/- 16.5 mu and 134.4 +/- 17.0 mu(p=0.004) in the superior quadrant, 97.4 +/- 11.5 mu and 90.2 +/- 15.3 mu (p=0.0001) in the nasal quadrant, 145.4 +/- 16.3 mu and 136.75 +/- 16.0 mu(p=0.002) in the inferior quadrant and 73.6 +/- 8.6 mu and 74.3 +/- 13.0 mu(p=0.659) in the temporal quadrant, respectively. There was 6.1-8% RNFL thickness difference between the values measured in the superior, nasal and inferior quadrants and the normative data used by the device; while compatibility of the values between temporal quadrants and normative data was obtained. Conclusion: The RNFL thickness in the superior, nasal and inferior quadrants were found to be statistically significant thicker in subjects included in the study. If the lower normative database used by the device were taken into account, errors in early diagnosis and the treatment of glaucoma would be inevitable. The initial data of our continuing study, reveal that the RNFL thickness values in healthy subjects of our population might not be plug-compatible with the normative database used by the device and this may result in a need to develop Turkish normative database.
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    Is Single Measurement Enough to Get a Reliable Result with Optical Coherence Tomography?
    (Turkish Ophthalmological Soc, 2012) Comez, Arzu Taskiran; Eser, Ilker; Bakar, Coskun; Komur, Baris
    Purpose: To evaluate the repeatability and reliability of retinal nerve fiber layer (RNFL) thickness measurements using optical coherence tomography (OCT). Material and Method: Two hundred sixty-six eyes of 135 subjects (glaucoma, glaucoma suspects and healthy) were included in this study. Three sequential inferior, superior, nasal and temporal RNFL thickness measurements were performed using Spectral OCT [Opko/OTI, Inc., Miami, FL] by one operator at one session without pupillary dilatation. The differences between these three measurements of each quadrant in each eye were compared in microns and percentages. Repeated measures analysis of variance was performed for statistical analysis. Reliability is measured by intraclass correlation coefficient (ICC) for each quadrant. Results: ICCs of all quadrants ranged between 0.77 and 0.92, with the measurements of nasal quadrant being the least reproducible and the inferior being the most reproducible of all quadrants. RNFL measurement errors over 20% were seen in 9.63% of nasal quadrant, 5.3% of temporal quadrant, 0.6% of superior quadrant and only 0.3% of inferior quadrant measurements. Discussion: In order to get more repeatable and reliable results with OCT, sequential measurements more than one should be considered. We believe that special attention is required in the analysis of data of nasal and temporal quadrants.
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    Normotensive Pseudoexfoliation Glaucoma Reports
    (Taylor & Francis Inc, 2013) Komur, Baris; Kara, Selcuk
    [Anstract Not Available]
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    Ocular aspergillosis: Obtaining a specimen is crucial for diagnosis. A report of three cases
    (Elsevier Science Bv, 2012) Comez, Arzu Taskiran; Komur, Baris; Alper Akçalı; Otkun, Muserref Tatman
    Aspergillus species have been implicated in a wide variety of primary ocular conditions, characterized by either slow and asymptomatic infection, or rapid, uncontrollable progression and sometimes death. The study design is a case series including chronic asymptomatic dacryocystitis, dacryocystitis with dacryoliths and endogenous endophthalmitis. Due to this variable clinical presentation of aspergillosis a high level of suspicion must be maintained as fulminant aspergillosis may lead to a rapidly progressive infection which may result in death. (C) 2012 International Society for Human and Animal Mycology. Published by Elsevier B.V.
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    Optic Disc Drusen Presenting with Binasal Hemianopia
    (Turkish Ophthalmological Soc, 2013) Tufan, Hasan Ali; Gencer, Baran; Komur, Baris; Kara, Selcuk; Kizildag, Betul; Uysal, Fatma
    Optic disc drusen (ODD) are defined as a form of calcific degeneration of the optic nerve. Visual field defects are seen in nearly 90% of the cases. We report a 32-year-old woman who was referred to our clinic with the complaint of longstanding blurred vision and nasal visual field defect in her both eyes. The diagnosis of ODD was made on the basis of clinical appearance of the optic nerves and confirmed by ancillary tests. Binasal visual field defect was observed in the automated visual field test. In conclusion, ophthalmologists should consider ODD in the differential diagnosis of advanced visual field loss and binasal hemianopia.