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    Chronic dacryocystitis secondary to Stenotrophomonas maltophilia and Staphylococcus aureus mixed infection
    (BMJ Publishing Group, 2014) Comez, Arzu Taskiran; Koklu, Asiye; Alper Akçalı
    A 40-year-old woman with a history of recurrent attacks of dacryocystitis for 2 years developed a lacrimal sac abscess. ?-Lactam antibiotics, considered the first-line treatment for dacryocystitis, were ineffective. She underwent dacryocystorhinostomy. Cultures from the lacrimal sac demonstrated the presence of Stenotrophomonas maltophilia and methicillin-sensitive Staphylococcus aureus, both of which are sensitive to trimethoprim- sulfamethoxazole. This rare and antibiotic-resistant bacterial species should be considered in atypical cases of dacryocystitis, and appropriate antibiotics should be started immediately. Copyright 2014 BMJ Publishing Group. All rights reserved.
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    Non-invasive assessment of corneal and conjunctival deterioration in soft contact lens users using anterior segment optical coherence tomography
    (Taylor & Francis Ltd, 2016) Ersan, Ismail; Arikan, Sedat; Kara, Selcuk; Gencer, Baran; Koklu, Asiye; Tufan, Hasan Ali
    Background The aim was to evaluate the corneal and bulbar conjunctival thicknesses of soft contact lens (SCL) wearers using anterior segment optical coherence tomography (AS-OCT). Methods The epithelial and overall thicknesses of both the central cornea and the infero-temporal bulbar conjunctiva of SCL wearers (30 subjects) were obtained by Cirrus HD-OCT and compared with those of refraction-matched controls (30 subjects) and patients with emmetropia (30 subjects). Results The mean corneal epithelial thicknesses in SCL wearing, spectacle-wearing and emmetropic groups were 48.97 +/- 5.45, 52.18 +/- 4.84 and 53.18 +/- 5.05 mu m, respectively. The corneal epithelium of members of the SCL group was significantly thinner than in both the spectacles and emmetropic groups (p = 0.044 and 0.006, respectively), whereas the central corneal thickness did not differ between groups (p = 0.210). The mean conjunctival epithelial thicknesses in SCL, spectacles and emmetropic groups were 41.50 +/- 7.75, 54.33 +/- 8.39 and 49.10 +/- 7.11 mu m, respectively. Conjunctival epithelium in the SCL group was significantly thinner than in both spectacle-wearing and emmetropic groups (p < 0.001 and p = 0.001, respectively). The conjunctiva was significantly thinner in the SCL group compared to the spectacles group (p = 0.001) but not the emmetropic group. Conclusions Contact lens wear is related to thinning of both corneal and conjunctival layers. AS-OCT is a non-invasive and clinically applicable technique for assessing the involvement of the cornea and conjunctiva in contact lens wearers.