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Öğe Effects of High Levels of Copper Supplementation to the Diet on some Blood Values and Thyroid Hormones in Japanese Quails (Coturnix coturnix japonica)(Kafkas Univ, Veteriner Fakultesi Dergisi, 2011) Onder, Feyyaz; Cenesiz, Metin; Kaya, Mehmet; Uzun, Metehan; Karademir, GulerIn this study was aimed to determine the effects of high levels of copper supplementation on some blood values and thyroid hormones in Japanese quails (Coturnix coturnix japonica). It was used totally 64 Japanese quail (one-day-old) as material in the study. Chicks were divided into four groups and they were given 0 mg/kg (control, group I), 100 mg/kg (group II), 250 (group III) and 500 mg/kg (group IV) copper in addition to their concentrate for 40 days. There were no difference hematocrit value, leukocyte number, differential leukocyte number, serum thyroid stimulating hormone (TSH) and free triiodothyronine levels (FT3) between the groups (P > 0.05). Serum copper levels were enhanced in copper supplemented groups (group II, III, IV) (P < 0.05). Copper supplementation to diet was induced to reduce the serum free thyroxine and erythrocyte number in all experimental groups (group II, III, IV) (P < 0.05). Hemoglobin amount were enhanced significantly (P < 0.05) in groups III and IV compared with control group and group II. It was induced to reduce in weight gain the 500 mg/kg Cu supplementation to the diet in compared with other groups (P < 0.05). As a result, the findings obtained from in this study is important that in terms of to reveal effects of excessive copper on thyroid hormones and to be used as a source prospective investigations.Öğe Japon bıldırcınlarında (Coturnix coturnix japonica) rasyona yüksek düzeylerde bakır ilavesinin tiroit hormonları ve bazı kan değerleri üzerine etkisi(2011) Önder, Feyyaz; Çenesiz, Metin; Kaya, Mehmet; Uzun, Metehan; Karademir, GülerBu araştırmada Japon bıldırcınlarında (Coturnix coturnix japonica) rasyona yüksek düzeylerde bakır ilavesinin tiroit hormonları vebazı kan değerleri üzerine etkilerinin belirlenmesi amaçlanmıştır. Araştırmada materyal olarak 1 günlük toplam 64 Japon bıldırcınıkullanıldı. Civcivler 4 gruba ayrıldı ve 40 gün süreyle 0 mg/kg (kontrol, grup I), 100 mg/kg (grup II), 250 mg/kg (grup III) ve 500 mg/kg(grup IV) bakır ilave edilen rasyonla beslendi. Hematokrit değer, akyuvar sayısı, akyuvarların yüzde oranı, serum tiroit uyarıcı hormon(TSH) ve serbest triiyodotironin (ST3) düzeyleri gruplar arasında farklılık göstermedi (P>0.05). Serum bakır düzeyleri bakır ilave edilengruplarda (grup II, III, IV) arttı (P<0.05). Rasyona bakır ilavesi bütün deneme gruplarında (grup II, III, IV) alyuvar sayısı ve serum serbest$ST_4$ düzeylerinde azalmaya (P<0.05) neden oldu. Hemoglobin miktarı kontrol grubu ve grup II ile karşılaştırıldığında grup III ve grup IV’teönemli bir şekilde (P<0.05) arttı. Rasyona 500 mg/kg bakır ilavesi grup IV’te, diğer gruplarla karşılaştırıldığında canlı ağırlık kazancındaazalmaya neden oldu (P<0.05). Sonuç olarak, bu araştırmada elde edilen veriler, bakır fazlalığının tiroit hormonları üzerine etkileriniortaya koyması ve ileride yapılacak araştırmaları kaynak teşkil etmesi bakımından önemlidir.Öğe Studies on mononuclear chelates derived from substituted Schiff-base ligands (part 6): synthesis and characterization of a new 3-ethoxysalicyliden-p-aminoacetophenoneoxime and its complexes with cobalt(II), niekel(II), copper(II) and zinc(II)(Taylor & Francis Ltd, 2007) Canpolat, Erdal; Kaya, Mehmet; Oztuerk, Omer FarukSchiff-base complexes of cobalt(II), nickel(II), copper(II)and, zinc(II) with 3-ethoxysalicyliden-p-aminoacetophenoneoxime (HL) were prepared and characterized on the basis of elemental analyses, 1R, H-1- and C-13-NMR, electronic spectra, magnetic susceptibility measurements, molar conductivity and thermogravimetric analyses (TGA). A tetrahedral geometry has been assigned to the complexes.Öğe Zinc(II) phthalocyanine containing Schiff base containing sulfonamide: synthesis, characterization, photophysical, and photochemical properties(Taylor & Francis Ltd, 2018) Sahal, Hakan; Piskin, Mehmet; Organ, G. Atiye; Ozturk, O. Faruk; Kaya, Mehmet; Canpolat, ErdalSynthesis and characterization of (E)-4-((5-bromo-2-(lambda(1)-oxidanyl)benzylidene)amino)-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide (1), its substituted phthalonitrile derivative (2), and its tetra substituted zinc(II) phthalocyanine complex (3) were performed. Compounds 1, 2, and 3 were characterized by methods such as elemental analyses, FT-IR, H-1-NMR, C-13-NMR (except for 3), and MALDI-TOF mass spectra. The photophysical and photochemical properties of this substituted zinc(II) phthalocyanine complex aimed to be used as a photosensitizer were investigated in DMSO solution for determination of their photosensitizing abilities in photocatalytic applications such as photodynamic therapy (PDT). The influence of the substituent as a bioactive compound on the phthalocyanine skeleton on spectroscopic, photophysical, and photochemical properties were also determined and compared with unsubstituted zinc(II) phthalocyanine and some zinc(II) phthalocyanines containing different substituents previously studied. According to photophysical and photochemical investigations, 3 has potential as a photosensitizer for PDT. [GRAPHICS] .