Yazar "Kartal, Burcu" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • [ X ]
    Öğe
    Development and application of a sensitive, disposable and low-cost electrochemical sensing platform for an antimalarial drug: amodiaquine based on poly(calcein)-modified pencil graphite electrode
    (Taylor & Francis Ltd, 2022) Karakaya, Serkan; Kartal, Burcu; Dilgin, Yusuf
    In this study, an electrochemical sensor towards the determination of an antimalarial drug, amodiaquine (Adqn), was performed. The proposed sensor was fabricated by electro-polymerisation of calcein (CCN) onto pencil graphite electrode (PGE). The electrochemical behaviour of 0.40 mM Adqn at both poly(calcein)-modified pencil graphite electrode (poly(CCN)/PGE) and bare PGE was evaluated in pH 3.0 Britton-Robinson buffer solution by cyclic voltammetry (CV) method. The voltammograms indicated that poly(CCN)/PGE presents a remarkable response towards oxidation and reduction of Adqn compared with PGE. The characterisation studies at poly(CCN)/PGE were performed by recording the electrochemical impedance curves, scanning electron microscopy images and energy-dispersive X-ray spectra. To determine the analytical performance of the poly(CCN)/PGE, the parameters such as linear range, limit of detection and sensitivity were determined based on the oxidation of Adqn by differential pulse voltammetry (DPV) method and were calculated to be 0.50-25 mu M, 0.16 mu M and 20.566 mu A mu M-1, respectively. The recovery studies at poly(CCN)/PGE were carried out with various matrixes (tap water, artificial blood and maternal milk) by DPV-spike methods, and the high recovery values (99.2-100.6%) confirmed that poly(CCN)/PGE can be used towards sensitive and accurate determination of Adqn in different sample matrixes containing Adqn.
  • [ X ]
    Öğe
    Polimerik lif katkılı güçlendirilmiş jeopolimer kompozit malzeme üretimi
    (Çanakkale Onsekiz Mart Üniversitesi, 2019) Kartal, Burcu; Cengiz, Uğur
    Bu çalışmada sentetik lif takviyeli jeopolimer betonun yapısal ve malzeme özellikleri araştırılmıştır. Jeopolimerler, normal sıcaklık koşullarında reaktif alümina silikat malzemelerinin ve silikat çözeltilerinin polikondensasyon reaksiyonu ile oluşan kristal olmayan alümina silikat polimerleridir. Mekanizma farklı SiO2, Al2O3, Na2O-K2O ve H2O oranlarından oluşan reaksiyona dayanmaktadır. Lif katkılı jeopolimer malzemelerin kimyasal bileşimlerine bağlı olarak; kanalizasyon boru ürünleri, ateş ve kimyasallara dayanıklı duvar panelleri, koruyucu kaplamalar ve tamir malzemeleri, püskürtme beton ve yüksek performanslı lif katkılı laminatlar gibi çeşitli uygulamalarda kullanılabilmektedir. Bu çalışmada, liflerin metakaolin bazlı jeopolimer betonun mukavemetine etkisine odaklanılmıştır. Lif oranı ağırlıkça % 0-1 arasında tutulmuştur. SiO2/Al2O: 3, Na2O/Al2O: 1, H2O/Na2O: 18 molar oranı sabitlenmiştir. Mekanik karakterizasyon çalışmaları, basınç ve eğilme dayanımı testleri ile gerçekleştirilmiştir. Jeopolimerin yapısal analizleri ve başlangıç materyalleri de XRD, XRF ve FTIR ile araştırılmıştır.
  • [ X ]
    Öğe
    Ultrasensitive voltammetric detection of an antimalarial drug (amodiaquine) at a disposable and low cost electrode
    (Springer Wien, 2020) Karakaya, Serkan; Kartal, Burcu; Dilgin, Yusuf
    In this study, an ultrasensitive electrochemical determination of an antimalarial drug, amodiaquine (ADQ), was described at a cheap and disposable pencil graphite electrode (PGE) which offers a renewable sensing surface for each measurement. The electrochemical behavior of ADQ was investigated on various carboneous electrodes. Cyclic voltammograms showed that ADQ gives reversible peaks at all electrodes. However, the highest currents for oxidation of ADQ and reduction of the oxidized form of ADQ (ADQ((Ox))) among the carboneous electrodes were obtained in the case of using PGE and these redox couple become more reversible and sharper at PGE than the other electrodes. DP voltammograms also showed that the oxidation peak current of ADQ at PGE is about five times higher than at other electrodes. All these results indicate that bare PGE without any modification exhibits an excellent electrocatalytic activity towards oxidation of ADQ. DP voltammetric studies show a wide linear dynamic range from 1.0 to 200 nM with a detection limit and sensitivity of 0.30 nM and 50 mu A mu M-1, respectively. The recovery of ADQ spiked into some different samples was studied. Obtained recovery values (99.2-102.0%) confirmed that non-modified PGE can be used for the ultrasensitive and accurate electrochemical quantification of ADQ in different samples.