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  1. Ana Sayfa
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Yazar "Karcioglu, Ozgur" seçeneğine göre listele

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    A Killer in Disguise: Button Battery Ingestions in Acute Care
    (Bentham Science Publ Ltd, 2025) Akman, Canan; Karcioglu, Ozgur; Ozturk, Goksu Afacan; Ucar, Asli Bahar
    Ingestion of button batteries (BB) represents a substantial health hazard, causing more common and severe complications than most other ingested objects. While the primary mechanism of injury is alkaline caustic injury (mediated by hydroxide ions produced through electrolysis at the site of the button battery), additional pathophysiological processes include pressure-induced necrosis, accumulation of hydroxide compounds at the battery's negative pole, direct caustic tissue injury, and potential heavy metal toxicity. Full-thickness burns, esophageal perforation, tracheoesophageal and aortoesophageal fistulas are encountered shortly after exposure. Vocal cord paralysis due to BB ingestion appears to be an early sign to predict the severity of the condition. Besides expedient removal, mitigation strategies are the key to the management. Pre-BB removal using honey or sucralfate and post-removal sterile acetic acid irrigation in the operation room can alleviate complication rates. This review is intended to cover and summarize all aspects of these incidents to provide information to clinicians and healthcare personnel.
  • [ X ]
    Öğe
    A Pharmacological Update and Safety Analysis of Medications for Smoking Cessation: Which Ones to Use?
    (Bentham Science Publ Ltd, 2025) Akman, Canan; Akgun, Feride Sinem; Ozel, Betul Akbuga; Ozkaya, Bilgen; Ozturk, Goksu Afacan; Karcioglu, Ozgur
    Interventions to reduce smoking prevalence aim to help patients quit smoking to cut down its hazards and related impairments in human beings. Pharmacological treatments are recommended for those with high levels of addiction because of severe physical and psychological dependence. Use of pharmacotherapy can double the odds of successful quitting. Nicotine replacement therapy (NRT), drug treatment regimens including nicotinic receptor agonists (varenicline), dopamine and norepinephrine reuptake inhibitors (bupropion), cytisinicline (cytisine), and combination therapy (NRT + medication) can be employed on a case-by-case basis. Furthermore, varenicline has been found to be more effective than the other agents in most studies. The most common adverse effects of pharmacological agents include depression, nausea, anxiety, abnormal dreams, and insomnia. On the other hand, electronic cigarettes offer another alternative to aid in smoking cessation (SC). Endurance of SC is mostly related to the employment of combined approaches, such as counselling and pharmacotherapy. This study is designed to provide an up-to-date overview of the contemporary approach to interventions aimed at helping patients in SC.
  • [ X ]
    Öğe
    Approach to the transplanted patient in acute care: a comprehensive update
    (Mre Press, 2025) Akman, Canan; Karcioglu, Ozgur
    Organ transplant patients present to emergency departments (EDs) for conditions often associated with transplantation due to changing anatomy, denervated allograft and immunosuppression. Infections and rejection are among the most feared problems in these patients. It is necessary to maintain a high index of suspicion. The process should be carried out in a multidisciplinary fashion with the transplantation team including specialists in infectious diseases. When evaluating these patients, conditions that are easily managed in other patients should be carefully investigated. Emergency care providers should recognize infections and other complications, obtain diagnostic work up, initiate empirical treatment and consider specialty consultation and inpatient admission. Even if these patients are referred to hospitals for reasons unrelated to transplantation, healthcare providers need to know their differences, the expected effects of the drugs to be administered, and to be aware of probable drug interactions while their treatment is being planned.

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