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    Are Mental Health Problems and Mindfulness Awareness Related to Levothyroxine Replacement in Adolescent Patients With Hashimoto's Thyroiditis?
    (SAGE Publications Inc., 2023) Uzun, Mehmet Erdem; Kaymaz, Nazan; Kara, Özlem; Kasap, Tolga
    Considering the possible adverse effects of thyroid autoantibodies on the brain, the present study aimed to investigate whether there was a difference in mental health difficulties and mindfulness awareness levels between subclinical Hashimoto’s thyroiditis patients with and without levothyroxine (LT4) use. A case-control study was conducted. The Strengths and Difficulties Questionnaire (SDQ) and the Mindful Attention Awareness Scale (MAAS) were used to screen mental health difficulties and mindfulness awareness. Scale scores were compared by performing correlation analysis between the groups with respect to LT4 use and thyroid autoantibodies. Levothyroxine alone does not affect scale results. Higher thyroid peroxidase antibody (TPOAb) titers were positively correlated with the behavioral problems subscale of the SDQ, while awareness level in patients was inversely correlated with higher thyroglobulin antibody (TgAb) levels.
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    Examination of relationship factors between psychological resilience and social support in adolescent obesity
    (Elsevier, 2023) Uzun, Mehmet Erdem; Kara, Özlem; Şirin, Hande; Kaymaz, Nazan
    Purpose: Childhood obesity is one of the most severe public health problems, and psychiatric conditions have been associated with obesity. In this study, we aimed to investigate psychological resilience and possible related factors in adolescents with obesity. Method: The study included 90 adolescents with obesity and 100 healthy adolescents of similar age. Data were collected using a sociodemographic information form, the Child and Youth Resilience Measure-28 (CYRM-28), and the Multidimensional Scale of Perceived Social Support. Scale scores were compared by Pearson's correlation coefficient test with SPSS-23. Multiple linear regression was performed to describe the relationships between variables. Results: The adolescents participating in the study were similar in terms of age and gender. Psychological resilience and social support in the obesity group were lower than in the control group (p < 0.05). A negative relationship was found between body mass index (BMI) and resilience levels of adolescents with obesity, and a positive relationship was found between social support and resilience levels (p = 0.027 and p < 0.001, respectively). The perceived family and significant other social support subscale scores of adolescents in the obesity group were significantly lower than in the control group (p = 0.037 and p = 0.023, respectively). The most related variable with the CYRM-28 was the level of perceived social support: standardized β = 0.409; t(151) = 5.626; p < 0.001. Conclusion: A higher BMI has a negative effect on psychological resilience, and family support tends to be lower in these cases. New studies are needed to clarify whether this result is one of the causes of obesity or one of its consequences.
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    The Impact of BMI on Self-Concept in Adolescents with Pubertal Gynecomastia
    (Uludağ Üniversitesi, 2025) Kaymaz, Nazan; Kara, Özlem; Kasap, Tolga; Uzun, Mehmet Erdem; Şirin, Hande
    Introduction Physiological changes in the body may result in anxiety and impaired self-concept during adolescence. Although temporary, pubertal gynecomastia (PG) may cause negative emotions that interrupt the development of self-concept by causing a physical appearance that does not fit the male gender. This paper aimed to identify whether the self-concept level of adolescents with PG is moderated by their anthropometrics. Materials and Methods This case-control study included adolescent males, with pubertal stage assessed using the Marshall and Tanner criteria. PG was diagnosed by palpation of a subareolar glandular disc. Anthropometric measurements were obtained by trained pediatric endocrinology clinic staff, and self-concept was evaluated using the Piers-Harris Children’s Self-Concept Scale (PHCSCS). To specify relationships correlation and regression analysis were examined. Results The study included 38 adolescents with PG and 61 age- and pubertal stage-matched controls. BMI was significantly higher in the PG group, and self-concept scores declined with increasing BMI (p=0.044; r=-0.437, p=0.006). PG subjects at Tanner Stage 3 were shorter than controls (p=0.03) and had lower happiness and behavior subscale scores (p=0.01; p=0.04). PG duration was negatively correlated with total self-concept (r=-0.400, p=0.013) and the subscales of happiness (r=-0.456), behavior (r=-0.334), and physical appearance (r=-0.354). Conclusion Adolescents with PG demonstrated lower self-concept, particularly in relation to higher BMI, shorter stature at mid-puberty, and prolonged symptom duration. These findings highlight the need for early psychosocial support in affected individuals.
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    The Impact of Lipomastia on Self-Esteem and Social Anxiety in Adolescents with Obesity
    (Canadian Acad Child & Adolescent Psychiatry, 2025) Kara, Özlem; Kaymaz, Nazan; Şirin, Hande; Uzun, Mehmet Erdem
    Background: Obesity can negatively impact adolescents' self-esteem, and lipomastia can further complicate the situation. Objective: The current study endeavors to examine the influence of lipomastia on the levels of social anxiety and self-esteem in individuals with obesity. Methods: Seventy adolescent male outpatients with obesity completed a form of demographics, the SAS-A (Social Anxiety Scale for Adolescents), and the Rosenberg Self-Esteem Scale (RSES-10 item). Participants were stratified according to the presence of lipomastia, and correlation analyses were conducted to investigate the association between social anxiety and self-esteem in relation to lipomastia. Results: No significant difference was found between the lipomastia and non-lipomastia groups regarding self-esteem. While the lipomastia group had slightly higher overall social anxiety scores, significant differences were noted only in fear of negative evaluation. There was no relationship between the SAS-A total score and anthropometric measurements in both groups. However, a negative relationship was observed between self-esteem and anthropometric measurements in the lipomastia group, whereas such a relationship was not observed in the control group. Conclusion: Adolescents with lipomastia showed higher social anxiety, particularly fear of negative evaluation, despite similar demographic and anthropometric characteristics to their peers. Higher BMI correlated with lower self-esteem, highlighting the complex interplay between body image, self-esteem, and social anxiety. These findings underscore the need for targeted interventions to support adolescents with obesity and lipomastia.

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