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Öğe Effect of high sound wave on ovarian tissue: an experimental study(Diagnosis Press, 2021) Kanbur, Savas; Sagir, DilekAfter air pollution, the most important environmental factor threatening human health is noise. Physiologic damage or psychological damage can occur because of noise. Increased oxidative stress, vascular changes and mechanical trauma may be responsible for the physiologic damage mechanism of noise. This study aimed to reveal the effect of noise on follicles in ovaries. In the study, a total of 30 female Wistar albino rats (12 weeks old) were randomly divided into three groups (n = 10): the control group, no treatment; the sham group, exposed to stress conditions (but not to any high waves) in a special room at the same time as the high sound wave group; and the high sound wave (HSW) group, exposed to HSW in a special room for 28 days. At the end of the 28th day, the rats were sacrificed and ovarian tissues were harvested. Stereologic and biochemical analyses were performed. All stereologic volumetric parameters and Gonadal Somatic Index (GSI) values, lipid peroxidation (LPO) and glutathione (GSH) levels in all groups were evaluated statistically, and significant differences were found between the control and HSW, sham and HSW groups, respectively. However, no statistical difference was found between the control and sham groups. A decrease in catalase (CAT) and superoxide dismutase (SOD) activities were found in the HSW group compared with the control and sham groups, suggesting that noise can cause oxidative stress and damage to the ovaries.Öğe Evaluation of In-vitro Anticandidal Activity of 99 Different Commercial Plant Extract, Fixed and Essential Oils against Vaginal Candida albicans Isolates(Kahramanmaras Sutcu Imam Univ Rektorlugu, 2023) Ates, Gulcin Ozcan; Kanbur, SavasPlant extracts (PE), fixed oils (FO) and essential oils (EO) are used in traditional medicine to treat various diseases. This study evaluated the anticandidal activity of 100 different commercially available PEs, FOs, and EOs against 19 Candida albicans vaginal isolates and C. albicans ATCC 10231. It was determined that 20 EOs and FOs had anticandidal activity. Piper nigrum FO, pine turpentine EO, pine tar EO, and Eugenia caryophyllata EO showed the highest anticandidal activity. The minimum inhibitory concentrations ( MIC) and minimum fungicidal concentrations (MFC) values of these FO and EOs were between 0.125 and 2 mu L mL(-1). The volatile components of these FOs and EOs were determined by GC-MS analysis. There were six components in E. caryophyllata EO, 38 in Pine turpentine EO, 39 in P. nigrum FO, and 119 in Pine tar EO. In conclusion, this FOs and EOs can be used to treat vulvovaginal candidiasis.Öğe INVESTIGATION OF THE EFFECT OF NOISY ENVIRONMENT ON EMPLOYEES' VISUAL ATTENTION(Parlar Scientific Publications (P S P), 2020) Kanbur, Savas; Cinar, UlasOccupational health and safety mainly aims to provide a safe working environment free from risk factors. Personal errors come first among the factors affecting occupational accidents and occupational diseases. The deficiency in visual attention is a significant factor that can contribute to erroneous circumstances and actions that may have major consequences. Environmental risk factors influence several parameters directly or depending on the exposure period and severity. Noise is a risk factor that has proven adverse effects on the physiological and psychological characteristics of individuals and has a risk of exposure in almost every area. In this study, the aim was to specify the effect of noisy work environment on the visual and sustainable attention level of the employees. A workgroup was created from occupational safety professionals, where the attention factor occupies a very important place due to the nature of their work. To assess the level of visual focus for the working group, a test explicitly designed for this study was applied at various noise levels and for different times at the maximum appropriate sound intensity. Statistically analyzed data were obtained. Accordingly, the detrimental effect of noise level at 70 dB and above on visual attention was calculated. In addition, as the exposure time increases, the significance of this effect has increased and this situation has been interpreted as the negative effect of noise exposure in the name of sustainable visual attention.Öğe The Effects of Heat Stress on Haematological Parameters in Production Department of Food Industry Employees(Pakistan Medical Assoc, 2023) Kanbur, Savas; Sayin, IrmakObjective: To investigate the effects of heat stress on some haematological parameters among food industry employees working in the production department. Method: The ambispective, single-centre, case-control study was conducted from December 1, 2016, to June 6, 2018, at Istanbul Gedik University and the Okan University, Istanbul, which is part of the Marmara region of Turkey. The study comprised subjects of either gender aged 22-57 years. Those working in the food industry were the cases in group A, while healthy controls formed group B. Within group A, subjects who were office workers formed subgroup A1, while those in the production department working in the heat treatment areas exposed to high temperatures formed subgroup A2. Heat stress in the environment was evaluated using the Wet Bulb Globe Temperature index. Peripheral blood haemoglobin and platelet levels, neutrophil-lymphocyte ratio and platelet-lymphocyte ratio were compared between the cases and the controls. Data was analysed using SPSS 22. Results: Of the 257 subjects, 139(54.1%) were women and 118 ( 45.9%) were men. The overall mean age was 35.07 +/- 7.32 years. There were 143(55.6%) subjects in group A and 114(44.4%) in group B. Within group A, 19(13.3%) subjects were in subgroup A1 and 124(86.7%) in subgroup A2. The mean working duration for group A was 9.95 +/- 4.37 years (range 5-24 years). Haemoglobin and platelet levels were significantly lower and the neutrophil-lymphocyte ratio was significantly higher in subgroup A2 compared to those in subgroup A1 and group B (p<0.05). There was no significant difference in terms of platelet-lymphocyte ratio (p=0.486). Conclusion: Differences in haematological parameters were significantly different in individuals who worked in the production department and were exposed to heat stress compared to those who did not.
