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    Öğe
    Brucellosis in childhood: retrospective evaluation of 37 cases and review of the literature
    (2022) Çelik, Taylan; Kaan, Emre
    Introduction: The aim of this study is to evaluate the demographic, clinical and laboratory characteristics and treatment results of pediatric patients followed up with the diagnosis of brucellosis in our clinic. Methods: Patients who were followed up with the diagnosis of brucellosis in Kayseri Training and Research Hospital, Pediatric Infectious Diseases Clinic between October 2016 and December 2018 were retrospectively analyzed. Results: A total of 37 patients, 26 (70.3%) male, were included in the study. The mean age of the patients whose ages ranged from 1 to 17 years was 9.3±4.3 years. Unpasteurized milk and/or dairy products were consumed in 86.5% of the patients and 48.6% had a family history of brucellosis. Joint pain (75.7%) was the most common presenting complaint. In the laboratory evaluation, 8.1% of the patients had leukopenia, 2.7% had thrombocytopenia and 21.4% had ALT elevation. Doxycycline plus rifampicin (43.2%) was the most commonly preferred treatment regimen. Addition of aminoglycoside to initial therapy in hospitalized patients was statistically higher than in outpatients (81.2% vs. 23.8%) (p=0.001). During the follow-up, relapse developed in a total of 4 (10.8%) patients, 3 of whom were outpatients. There was no statistical relationship between the initial treatment regimen and relapse (p=0.418). Conclusion: In conclusion, brucellosis should be kept in mind in terms of differential diagnosis in patients who present with joint pain in our country and who have cytopenia and/or isolated aminotransferase elevation in their investigations. Keywords: Child, Brucellosis, Leukopenia, Relapse, Thrombocytopenia
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    Öğe
    Çocuklarda tularemi; altı olgunun klinik, laboratuvar ve tedavi sonuçlarının değerlendirilmesi
    (Çanakkale Onsekiz Mart Üniversitesi, 2021) Çelik, Taylan; Kaan, Emre; Özcan, Eda
    Amaç: Tularemi, Francisella tularensis’in neden olduğu zoonotik bir enfeksiyon hastalığıdır. İn-sanlarda en sık ülseroglandüler formu olmak üzere, glandüler, pnömonik, orofaringeal, oküloglandüler, intestinal ve tifoidal dahil olmak üzere çeşitli klinik formlara sahiptir. Çocuk Enfeksiyon Hasta-lıkları Polikliniğinde takip edilen altı olgu ile çocuklarda tularemiyi tartışmak istedik. Yöntem: Çocuk Enfeksiyon Hastalıkları Polikli-niği’nde tularemi tanısı ile takip edilen hastaların tıbbi verileri retrospektif olarak incelendi. Bulgular: Tularemi tanısı alan toplam 6 hastanın 2’si kız 4’ü erkekti. Yaşları 7-17 arasında değişi-yordu. Dört hasta şehir şebeke suyu, 2 hasta ise köy çeşmesinden su kullanıyordu. Şehir şebeke suyu kullanan iki hastanın kaynak suyu içme öyküsü vardı. Bir hastada orofaringeal, 5 hastada ise glandüler formda tularemi saptandı. Hastaların yakınmalarının başlangıç zamanından has-tanemize başvurusu arasında geçen medyan süre 30 gün (5-60) olarak tespit edildi. Hastalarımızın en sık başvuru yakınması boyunda şişlikti, bir has-tamız ise boğaz ağrısı yakınması ile başvurmuştu. Hastalardan beş tanesine ilk tercih olarak gentami-sin, diğer hastaya ise doksisiklin başlanmıştı. Başlangıç gentamisin tedavisine yanıt alınamayan hastalarda doksisiklin veya siprofloksasin tedavi değişikliği yapılmıştı. Tularemi etkili antibiyotik kulanım gününü 36.5 (14-52) gün olarak saptadık. Sonuç: Sonuç olarak, hastalığın ilerlemesini, teda-vi başarısızlığı ve cerrahi müdahale gereksinimi azaltmak için, erken tanı ve uygun antimikrobiyal tedavinin hızla başlanması çok önemlidir
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    Öğe
    Perianal Abscess in Children: Are Resistant Microorganisms a Real Problem?
    (Aves Yayincilik, Ibrahim Kara, 2022) Celik, Taylan; Kaan, Emre; Caglar, Ozgur
    Objective: Perianal abscess is a common purulent disease in daily pediatric practice caused by infection of perianal tissues and cavities. There is a strong male dominance in affected children less than two years old. In our study, we aimed to investigate the clinical and laboratory studies of cases diagnosed with perianal abscess in childhood. Material and Methods: Medical data followed by the diagnosis of perianal abscess by Kayseri Training and Research Hospital, Pediatric Infectious Diseases between October 2016, and June 2018, were retrospectively analyzed. Results: A total of 15 patients were followed up with a diagnosis of perianal abscess. Fourteen (93.3%) of the patients were male. Their average age was 19.10 +/- 8.86 months. Seven (46.6%) of the patients were less than six months old and 11 (73.3%) were younger than one year old. Fever was associated with only one (6.7%) correspondence complaints, 13 (86.6%) patients were brought close to perianal row swelling. Surgical drainage was applied to all 12 (80%) patients who were hospitalized and followed up. There was growth in the abscess culture in 10 (83.3%) of the patients. In 60% of the patients with culture growth, the agents were resistant microorganisms. In 50% of our hospitalized cases, treatment change was required according to the culture antibiogram results, and the combined use of meropenem and amikacin was preferred in these patients. Conclusion: In conclusion, although perianal abscesses are common in children, data on the management and treatment of the disease are limited. Our study highlights the benefit of routine abscess culture in the treatment of perianal abscesses.