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    The Role of Pneumococcal Pneumonia among CommunityAcquired Pneumonia in Adult Turkish Population: TurkCAP Study
    (AVES, 2021) Şenol, Esin; Çilli, Aykut; Günen, Hakan; Şener, Alper; Dumlu, Rıdvan; Ödemiş, Ayşe; Topçu, Ayşe Füsun; Yıldız, Yeşim; Güner, Rahmet; Özhasenekler, Ayhan; Mutlu, Birsen; Köktürk, Nurdan; Sevimli, Nurgül; Baykam, Nurcan; Yapar, Derya; Ekin, Selami; Polatlı, Mehmet; Eren Gök, Şebnem; Kılınç, Oğuz; Sayıner, Abdullah; Karaşahin, Ömer; Çuhadaroğlu, Çağlar; Sesin Kocagöz, Ayşe; Togan, Turhan; Arpağ, Hüseyin; Katı, Hakan; Köksal, İftihar; Aksoy, Firdevs; Hasanoğlu, Canan
    OBJECTIVE: To evaluate the rate of pneumococcal pneumonia (PP) among patients with community-acquired pneumonia (CAP) in Turkey and to investigate and compare features of PP and non-PP CAP patients. MATERIAL AND METHODS: This multicenter, non-interventional, prospective, observational study included adult CAP patients (age = 18 years). Diagnosis of PP was based on the presence of at least 1 positive laboratory test result for Streptococcus pneumoniae (blood culture or sputum culture or urinary antigen test [UAT]) in patients with radiographic findings of pneumonia. RESULTS: Four hundred sixty-five patients were diagnosed with CAP, of whom 59 (12.7%) had PP. The most common comorbidity was chronic obstructive pulmonary disease (30.1%). The mean age, smoking history, presence of chronic neurological disease, and CURB-65 score were significantly higher in PP patients, when compared to non-PP patients. In PP patients, 84.8% were diagnosed based ony on the UAT. The overall rate of PP patients among CAP was calculated as 22.8% considering the UAT sensitivity ratio of 63% (95% confidence interval: 45-81). The rate of intensive care treatment was higher in PP patients (P =.007). While no PP patients were vaccinated for pneumococcus, 3.8% of the non-PP patients were vaccinated (P =.235). Antibiotic use in the preceding 48 hours was higher in the non-PP group than in the PP group (31.8% vs. 11.1%, P =.002). The CURB-65 score and the rate of patients requiring inpatient treatment according to this score were higher in the PP group. CONCLUSION: The facts that PP patients were older and required intensive care treatment more frequently as compared to non-PP patients underline the burden of PP.