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Öğe Bibliometric analysis of primary central nervous system lymphoma(2023) Guven, Serkan; Alkan, SevilAim: Primary central nervous system lymphoma (PCNSL) is an important topic in hematology due to its rare, aggressive course, difficult diagnosis and special treatment requirements. This bibliometric analysis study aimed to examine PCNSL-related publications published since the last 2000 and to identify potential points of future research. Materials and Methods: Web of Science Core Collection documents published between 2000 and 2022 were analyzed using selected keywords. The obtained data were visualized with bibliometric tools. Publishing countries, organizations, journals, authors, references, and keywords were all examined comprehensively. Results: 1,160 articles on PCNSL published since 2000 were retrieved. These publications tend to focus on research in oncology (n=456, 39.310%), clinical neurology (n=354, 30.517%), and hematology (n=173, 14.914%). Search criteria revealed that 6,458 authors from 65 different countries and 1,570 organizations worldwide contributed to PCNSL articles. Conclusion: Studying research on PCNSL is crucial to improve our knowledge of this disease and to create new treatment strategies. It is very important to keep in mind that the characteristics and trends in PCNSL research may change over time as new findings and developments in the field are discovered. The results of this study may provide guidance for researchers working in this area.Öğe Examining posttraumatic growth among Turkish family caregivers of cancer patients(Nature Portfolio, 2024) Guven, Serkan; Topkaya, Nursel; Sahin, Ertugrul; Aras, Nur YagmurCancer is a deadly disease that affects millions of people worldwide and is a source of great difficulty, stress, and trauma not only for patients but also for their caregivers. The physical and emotional suffering that patients experience by patients can lead their caregivers to cope with constant anxiety, sadness, and uncertainty. Moreover, during the cancer treatment process, caregivers must make a great effort to meet the needs of patients and support them. This situation may negatively affect the quality of life and psychological health of cancer patients' caregivers and may lead them to experience trauma. The aim of this cross-sectional study was to examine posttraumatic growth's relationship with age, the transformative power of suffering, and hope in family caregivers of cancer patients. Participants consisted of 314 Turkish family caregivers of cancer patients (73.2% women; Mage = 39.89 years) selected by using convenience sampling method. Participants answered a data collection tool consisting of a demographic information form, the Posttraumatic Growth Inventory, Trait Hope Scale, and Transformative Power of Suffering Scale. Data were analyzed using descriptive statistics, the Pearson product-moment correlation coefficient analysis, simple mediation analysis, and moderated mediation analysis. The results of this study revealed that hope mediated the association between the transformative power of suffering and posttraumatic growth in family caregivers of cancer patients, whereas age moderated this relationship. Psychosocial support programs for cancer caregivers could benefit from incorporating interventions that explore the transformative potential of suffering and cultivate hope. Tailoring these interventions to address the specific needs of different age groups may enhance their effectiveness. Future researchers should investigate the factors associated with posttraumatic growth in caregivers across diverse cultures, age ranges, and cancer diagnoses.Öğe Psychometric Properties of the Depression Anxiety Stress Scales (DASS-42 and DASS-21) in Patients with Hematologic Malignancies(MDPI, 2025) Guven, Serkan; Sahin, Ertugrul; Topkaya, Nursel; Aydin, Oznur; Aktimur, Sude Hatun; Turgut, MehmetBackground/Objectives: Patients with hematologic malignancies undergo prolonged, intensive treatments involving frequent hospitalizations and experience debilitating side effects. Consequently, they are at increased risk of developing symptoms of depression, anxiety, and stress, which can undermine their quality of life. However, there is a scarcity of instruments validated for the simultaneous assessment of depression, anxiety, and stress within hematologic cancer populations. The aim of this study is to examine the construct validity, convergent and discriminant validity, and reliability of the Depression Anxiety Stress Scales (DASS-42 and DASS-21) among hematologic cancer patients. Methods: We collected data from 452 hematologic cancer patients across three studies. Results: Confirmatory factor analyses indicated that the theoretical correlated three-factor model and bifactor model for DASS-42 and DASS-21 responses were sufficient to explain the underlying factor structure of the scales in hematologic cancer patients. However, the bifactor model for DASS-42 and DASS-21 fit better with the data compared to the theoretical correlated three-factor model. In addition, we found the correlated three-factor model and the bifactor structure to exhibit scalar measurement invariance across gender for DASS-42 and DASS-21. DASS-42 and DASS-21 subscales demonstrated weak to strong negative correlations with measures of psychological well-being (happiness, well-being, life satisfaction) and strong positive correlations with measures of similar constructs (depression, anxiety, and stress), thereby supporting their convergent and discriminant validity with theoretically and empirically expected correlations with external criteria. The reliability analyses demonstrated that both DASS-42 and DASS-21 subscales exhibited strong internal consistency and test-retest reliability when assessing symptoms of depression, anxiety, and stress among patients with hematologic malignancies. Moreover, the item-scale convergent and discriminant validity analyses demonstrated that items exhibited higher corrected item-total correlations with their intended subscales than with other subscales across the DASS-42 and DASS-21, providing evidence for the distinct measurement properties of each subscale. Conclusions: The findings suggest that the DASS-42 and DASS-21 are psychometrically robust instruments for use in Turkish hematologic cancer patients.