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Öğe Is there any relationship between adverse pregnancy outcome and first trimester nuchal translucency measurements in normal karyotype fetuses?(Informa Healthcare, 2015) Uysal, Fatma; Cosar, Emine; Yucesoy, Kaya; Gencer, Meryem; Cevizci, Sibel; Gungor, Aysenur; Hacivelioglu, ServetAim: This study aims to research whether there is a relationship between first trimester nuchal translucency (NT) measurements and pregnancy complications such as gestational diabetes mellitus (GDM), gestational hypertension (GHT), intrauterine growth restriction (IUGR) and oligohydramnios. Method: This study included 225 singleton pregnancies attending Canakkale Onsekiz Mart University Obstetrics and Gynecology clinic for all monitoring and examinations, and gave birth at our clinic between January 2011 and December 2012. Data sources were clinical records and the hospital's automation system, and the study was planned as retrospective cohort. NT measurement was made between 10 weeks 3 days and 13 weeks 6 days gestation. For data analysis, the chi-square, Mann-Whitney U test and Spearman correlation were used. Results: Of pregnancies, in the study, 5 (2.2%) developed GDM, 6 (2.6%) developed GHT, 2 (0.89%) developed IUGR and 10 (4.4%) developed oligohydramnios. There was no correlation identified between NT measurements and development of GDM, GHT, IUGR and oligohydramnios. Conclusion: There was no relationship found between first trimester NT measurements and complications that could develop in pregnancy. For the first time in the literature, NT and oligohydramnios were studied and no relationship was observed.Öğe Is There Any Relationship Between Platelet Functions, Red Cell Distribution Width and Recurrent Pregnancy Loss?(Derman Medical Publ, 2015) Uysal, Ahmet; Incebiyik, Adnan; Hacivelioglu, Servet; Gencer, Meryem; Gungor, Aysenur; Cosar, EmineAim: Recurrent pregnancy loss (RPL) affects 1% pregnancies and its etiology is multi-factorial. Hypercoagulability might result in recurrent abortions; anticoagulant therapy could potentially increase the live-birth rate in subsequent pregnancies in women with unexplained recurrent abortions. Mean platelet volume (MPV) and platelet distribution width (PDW), are a parameter of platelet functions and may be a marker for increased platelet aggregability. In this study we aimed to determine whether MPV, PDW and red cell distribution width (RDW) values differ between patients with RPL and in healthy participants. Material and Method: A total of 50 RPL patients and 49 age matched healthy women were enrolled into the study. For all subjects following tests were performed: Hemoglobin, hematocrit, white blood cells counts (WBC), MPV, PDW, platelet count, RDW and thyroid stimulating hormone (TSH). Results: Compared with healthy controls there were no statistically differences in MPV and PDW between (p > 0.05, respectively) in women with RPL. However, RDW was significantly lower in patients with RPL than in group with control (p = 0.023,). Discussion: It was first shown in the literature that patients with RPL have no significance MPV and PDW than control subjects. However RDW levels were found that it was significantly related to recurrent pregnancy loss.Öğe Treatment of Vaginal Cuff Prolapses with Posterior Intravaginal Sling and Evaluation of Efficiency with International Consultation on Incontinence QuestionnaireVaginal Symptoms Method in the Long Term: Preliminary Results(Wiley, 2013) Balsak, Deniz; Uysal, Ahmet; Cavus, Yunus; Ince, Zehra; Acar, Zuat; Gungor, Aysenur; Hacivelioglu, ServetObjectives: The aim of this study was to research the efficiency of posterior intravaginal sling (PIVS) procedure in vaginal cuff prolapse, together with possible complications, long-term effects and effects of the method on vaginal and sexual function and quality of life of patients. This retrospective study comprised 21 patients with vaginal cuff prolapse. Methods: PIVS procedure was performed in 21 patients with vaginal cuff prolapse with quantification stages 2, 3, or 4 of pelvic organ prolapse. Patients were assessed according to the International Consultation on Incontinence QuestionnaireVaginal Symptoms before and after operation. Results: The average follow-up period was 24.6 months. The rate of surgical success was 100%, the rate of mesh erosion was 14.2% and the rate of dyspareunia was 33.3%. Vaginal symptom, sexual matter and quality of life scores were statistically significant in the postoperative period compared to the preoperative period (P = 0.001, P = 0.001, P = 0.001, respectively). Conclusion: PIVS is an effective and reliable method of treating vaginal cuff prolapse. However, its complication profile is not yet at an acceptable level. We believe that the rate of mesh erosion will regress to a more acceptable level with the improvement of mesh technology and postoperative method. The necessary incontinence surgery is easily performed together with PIVS procedure. PIVS restores the vaginal and sexual functions of patients and increases their quality of life significantly.