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Öğe An unusual and serious cause of gastritis: Emphysematous gastritis(Elsevier Masson, Corporation Office, 2015) Uysal, F.; Akbal, E.; Gunes, F.; Sacar, S.; Ozdemir, H.[Anstract Not Available]Öğe Are Small Adrenal Incidentalomas Solely a Radiological Finding?(Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh, 2015) Eroglu, M.; Erbag, G.; Turkon, H.; Binnetoglu, E.; Ozkul, F.; Gunes, F.; Sen, H.Objective: The criterium defining the threshold size of adrenal incidentaloma (AI) is a size greater than 1cm diameter. However, data concerning AI1cm in diameter is scant. The aim of this study was to evaluate the function of adrenal masses1cm and to compare them with adrenal masses>1cm. Materials and Methods: The study included 130 consecutive patients with AI (38 and 92 AI at 1cm and >1cm, respectively). The patients were evaluated according to demographic and hormonal characteristics. Results: The prevalence of SCS was 5.3 and 12% in AI1cm and >1cm diameter, respectively. Hyperaldosteronism was found only in patients with >1cm AI. Pheochromocytoma were not found in either group. Patients with >1cm AI had a higher prevalence of SCS and primary hyperaldosteronism than patients with 1cm AI, but the difference was not significant. The prevalence of diabetes and hypertension was high both in non-functional AI with 1cm and >1cm patients and showed no significant difference between the 2 groups. Conclusion: Our study is the first to focus on the clinical and hormonal characteristics of patients with 1cm AI. Those with AI1cm harboured SCS, as was the case for AI>1cm. Similar to AI>1cm, non-functional AI1cm also had a higher prevalence of diabetes and hypertension.Öğe Effects of Acute Pancreatitis on Plasma Total and Lipid Bound Sialic Acid Levels: An Experimental Study in Rats(Editura Celsius, 2014) Ozkan, O. F.; Cikman, O.; Roach, C.; Kemik, A. S.; Gunes, F.; Karaayvaz, M.Background: We investigated the relationship between serum levels of total sialic acid, lipid bound sialic acid and acute pancreatitis in a rat model of a common bile duct ligation induced acute pancreatitis. Methods: Twenty five Sprague-Dawley male rats weighing 250-300g were divided into two groups (n=10: control, n=15: experimental). In the control group only a sham laparotomy was performed. In the experimental group, acute pancreatitis was induced by common pancreatobiliary tract ligation. After 36 hours the rats were killed and amylase, serum total sialic acid, lipid bound sialic acid and lipid profiles were measured. Histopathological confirmation of acute pancreatitis was done using hematoxylin and eosin staining. Results: Mean amylase, total sialic acid (TSA) and lipid bound sialic acid (LBSA) measurements in the experimental group were significantly higher than in the control group. There was no significant difference in the lipid profiles between the two groups. Conclusion: Increased levels of TSA and LBSA can be useful as specific markers in the diagnosis of acute pancreatitis independent of serum lipid profile.Öğe IMPULSIVITY AND ATTENTION DEFICIT-HYPERACTIVITY SYMPTOMS AMONG FEMALE PATIENTS WITH OBESITY(Cambridge Univ Press, 2013) Karaahmet, E.; Altinbas, K.; Sen, H.; Gunes, F.; Bakim, B.; Konuk, N.[Anstract Not Available]Öğe Timing of Lidocaine Spray for Upper Gastrointestinal System Endoscopy and Effect on Quality for Patients(Georg Thieme Verlag Kg, 2014) Binnetoglu, E.; Akbal, E.; Kocak, E.; Koklu, S.; Gunes, F.Background: During the esophagogastroduodenoscopy the comfort of both the patient and the doctor performing the endoscopy topical anesthetic are used. However some discomfort from the use of topical anesthetics to suppress the gag reflex may be observed. We aimed to compare the effects of local spray given immediately with that given in the endoscopy waiting room in terms of oropharynx anesthesia, gag reflex, amount of secretion, endoscopy duration, and quality of the procedure. Methods: The patients were devided into two groups; Group 1 was anesthetized with lidocaine spray (Zylocaine spray 10 %) immediately before the procedure; while Group 2 was anesthetized in the preparation room. The patients did not use any other drugs, i.e., anti-anxiety medications, sedatives, etc. Results: The patients were randomly sorted into two groups, with 65 in the first group and 69 in the second. There was no significant difference between Group 1 and 2 in terms of age, gender, or educational level. The amount of secretion in Group 1 was significantly less compared to Group 2. There was no significant difference in terms of endoscopy duration, gag reflex, throat pain scores and the quality of the procedure. Conclusion: We showed that oropharynx anesthesia with lidocaine immediately before the procedure causes an important reduction in the amount of secretion. In this way the endoscopy practitioner can see the stomach mucosa more clearly. For this reason lidocaine administration immediately before the procedure may be safely given to patients.