Yazar "Gencer, Meryem" seçeneğine göre listele

Listeleniyor 1 - 20 / 37
  • [ X ]
    Öğe
    9qh+'liği Molar Gebelik İçin Bir Risk Faktörü mü?
    (2016) Güngör, Ayşe Nur Çakır; Sılan, Fatma; Kılınç, Nihal; Gencer, Meryem; Uludağ, Ahmet; Coşar, Emine; Koç, Evrim
    Polimorfizm olarak kabul edilen 9qh+'liğinin daha önce bazı sorunlara neden olduğunu gösteren çalışmalar olmakla birlikte molar gebelikte daha önce tanımlanmamıştır. Vakalarımız literatürdeki ilk iki 9qh+'liği ile birlikte tanımlanan molar gebelik vakası olması yönüyle önemlidir
  • [ X ]
    Öğe
    A giant chorioangioma of the placenta with favorable outcome: a rare case presentation with literature review
    (2016) Beyazit, Fatma; Göret, Ceren Canbey; Pek, Eren; Gencer, Meryem
    Chorioangioma, or hemangioma of the placenta, is the most frequent non-trophoblastic tumor of the placenta consisting of blood vessels and stroma. A great proportion of these tumors are small and well delineated within the placental parenchyma and have no or minimal adverse impact on the fetus. Unfortunately, large tumor size is linked to serious complications such as fetal anemia, hydrops and intrauterine death. This is probably because of arteriovenous shunts leading to progressive heart failure of the fetus. With the increasing rates of antenatal screenings with ultrasonography, prenatal diagnosis of these tumors is widely achieved. Here we report a case of giant placental chorioangioma diagnosed in the second trimester of pregnancy. The size of the tumor minimally increased during follow-up and at term, uncomplicated labor was achieved. Macroscopic and histologic examination confirmed the diagnosis
  • [ X ]
    Öğe
    Acne severity and the Global Acne Grading System in polycystic ovary syndrome
    (Elsevier Ireland Ltd, 2013) Hacivelioglu, Servet; Gungor, Ayse Nur Cakir; Gencer, Meryem; Uysal, Ahmet; Hizli, Deniz; Koc, Evrim; Cosar, Emine
    Objective: To evaluate the association between acne, quantified by the Global Acne Grading System (GAGS), and abnormal clinical and laboratory markers of androgen excess in patients with polycystic ovary syndrome (PCOS). Methods: The retrospective study included 133 patients with PCOS. Acne severity was quantified with the GAGS score, alopecia was graded with the Ludwig classification, and hirsutism was quantified with a modified Ferriman-Gallwey (FG) score. Results: The mean GAGS score was significantly greater in younger women, those with a lower BMI, and those with a higher FG score. There was no relation between the mean GAGS score and waist circumference, waist/hip ratio, androgen hormone levels (free testosterone, total testosterone, or dehydroepiandrosterone sulfate), sex-hormone-binding globulin level, or menstrual irregularity. Alopecia was significantly associated with an increased waist/hip ratio; there was no relation between alopecia and age, waist circumference, body mass index, FG score, androgen hormone levels, or menstrual irregularity. A weak positive correlation was observed between the GAGS and FG scores. Conclusion: The GAGS may provide more precise and comprehensive information about acne severity in obese or hirsute patients with PCOS because this grading system includes evaluation of the type (comedones, papules, pustules, nodules) and location (anatomic area) of acne lesions. (c) 2013 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
  • [ X ]
    Öğe
    Atrial conduction time, and left atrial mechanical and electromechanical functions in patients with polycystic ovary syndrome: interatrial conduction delay
    (Clinics Cardive Publ Pty Ltd, 2015) Gazi, Emine; Gencer, Meryem; Hanci, Volkan; Temiz, Ahmet; Altun, Burak; Barutcu, Ahmet; Gungor, Ayse Nur
    Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders of women during the reproductive period. Cardiovascular risk factors are more frequent in patients with PCOS. We aimed to investigate the P-wave dispersion (Pd), inter-and intra-atrial conduction time and mechanical functions of the left atrium (LA) in patients with PCOS. Methods: Forty-eight patients with PCOS and 38 normal healthy women were enrolled in this study. A 12-lead surface electrocardiogram was used to evaluate Pd. Left ventricular (LV) functions were measured using conventional and tissue Doppler imaging (TDI) methods. Inter-and intra-atrial conduction times were measured by TDI. LA volumes were measured echocardiographically with the biplane area-length method from the apical four-chamber view. Results: Heart rate (82.02 +/- 13.15 vs 74.24 +/- 11.02 bpm, p = 0.014) and Pd were significantly increased in the PCOS patients [ 27 +/- 5 vs 24 +/- 6 ms, p = 0.035]. Transmitral E/A ratio was significantly lower in the PCOS patients than in the controls (1.5 +/- 0.3 vs 1.7 +/- 0.4 m/s, p = 0.023). Passive emptying volume (12.54 +/- 4.39 vs 15.28 +/- 3.85 ml/m(2), p = 0.004) and passive emptying fraction [54.4 (21-69) vs 59.1% (28-74), p = 0.008] were significantly decreased in PCOS patients. Total emptying volume was significantly decreased (17.9 +/- 5.49 vs 20.67 +/- 4.29 ml/m(2), p = 0.018) in PCOS patients. Interatrial (19 +/- 7.4 vs 15 +/- 6.4 ms, p = 0.035) and intra-atrial [8.5 (1-19) vs 5 ms (1-20), p = 0.026] electromechanical delays were found to be significantly higher in PCOS patients. Conclusion: This study showed that patients with PCOS had increased inter-and intra-atrial conduction delays, and decreased LA passive emptying volumes and fractions.
  • [ X ]
    Öğe
    Comparison of olive oil and lanolin in the prevention of sore nipples in nursing mothers
    (2013) Gungor, Ayse Nur Cakir; Oguz, Sevilay; Vurur, Gulsen; Gencer, Meryem; Uysal, Ahmet; Hacivelioglu, Servet; Uludag, Aysegul
    [No abstract available]
  • [ X ]
    Öğe
    Does Omegaven have beneficial effects on a rat model of ovarian ischemia/reperfusion?
    (Elsevier Science Bv, 2014) Gungor, Ayse N. Cakir; Turkon, Hakan; Albayrak, Aynur; Ovali, Mehmet; Islimye, Mine; Gencer, Meryem; Hacivelioglu, Servet
    Objective: The beneficial effects of omega-3 fatty acids on an intestinal ischemia/reperfusion (I/R) model was shown previously. Therefore, we aimed to examine the potential beneficial effects of parenteral omega-3 fatty acids, a safe and inexpensive product, on a rat model of ovarian I/R. Study design: A group of 39 rats was divided into six groups. Group 1 (Sham Group; n = 6) underwent two laparotomies with a 3-h interval and their ovaries were removed 3 h later. Group 2 (torsion detorsion Group; n = 7) had their ovaries torsioned clockwise and fixed at 7200; 3 h later a detorsion operation was done and after another 3 h, their ovaries were removed. Group 3 (n = 7) and Group 4 (n = 7) received the same treatment as Group 2; however, half an hour prior to detorsion, these rats received Omegaven at 1 mL/kg and 5 mL/kg, respectively. Group 5 (n = 6) and Group 6 (n = 6) received the same treatment as Group 1; however, half an hour prior to the second laparotomy, these rats received Omegaven at 1 mL/kg and 5 mL/kg, respectively. One ovary from each rat was evaluated histologically by hematoxylin and eosin (H&E) staining and the other ovary was homogenized and evaluated for total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI). Results: While we failed to show any significant relationship among groups in oxidative parameters, there was a significant worsening in the torsion detorsion group in histological evaluation. High Omegaven doses, but not low doses, improved tissue injury scores of torsioned and detorsioned ovaries to the levels observed in the control group. Conclusion: Omegaven improves the detrimental effects of ovarian I/R when used in sufficient doses. Its effects and dose adjustment on women with ovarian torsion must be investigated by further studies. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
  • [ X ]
    Öğe
    Effects of Melatonin on Blood Pressure, Oxidative Stress and Placental Expressions of TNF?, IL-6, VEGF and sFlt-1 in RUPP Rat Model of Preeclampsia
    (Elsevier Science Inc, 2017) Uzun, Metehan; Gencer, Meryem; Turkon, Hakan; Oztopuz, Rahime Ozlem; Demir, Ufuk; Ovali, Mehmet Akif
    [Anstract Not Available]
  • [ X ]
    Öğe
    Effects of vaginal discharge on female sexual function
    (Wiley, 2014) Gungor, Ayse N. C.; Uludag, Aysegul; Sahin, Melih; Gencer, Meryem; Uysal, Ahmet
    Objective: To assess the effects of vaginal discharge on female sexual dysfunction (FSD) by using the Female Sexual Function Index (FSFI). Methods: In a study at a university hospital in Canakkale, Turkey, women affected by vaginal discharge and age-matched healthy control women were recruited between January and December 2012. Women were grouped in accordance with their vaginal discharge complaints and each participant com- pleted the FSFI questionnaire. Results: A total of 114 women were included in the study. Women in the first group (n = 58) had no vaginal discharge or had physiologic vaginal discharge, those in the second group (n = 29) had abnormal vaginal discharge with itching, and those in the third group (n = 27) had abnormal vaginal discharge without itching. Compared with the first group, women in the second and third groups had higher FSFI scores for desire, arousal, orgasm, and pain, in addition to higher overall FSFI scores. Women with genital malodor had significantly higher FSFI scores than patients without genital malodor (23.83 +/- 5.07 vs 21.15 +/- 4.78; P = 0.008). Conclusion: Women with abnormal vaginal discharges were found to have better FSFI scores for some domains. This finding may be attributed to the adverse effects of sexual intercourse on vaginal infections. (C) 2013 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
  • [ X ]
    Öğe
    Ektopik Gebelik Klinik Seyrini ve Tedavi Sonuçlarını Etkileyen Faktörlerin Retrospektif Analizi
    (2017) Beyazıt, Fatma; Pek, Eren; Çakır, Ayşenur Güngör; Gencer, Meryem; Uysal, Ahmet; Hacıvelioğlu, Servet; Ünsal, Mesut Abdulkerim
    Amaç: Ektopik gebelik (EG) embryonun uterin kavite dışında bir yerde implante olmasıyla karakterize ciddi bir medikal durumdur. Uygun tedavi verilmediğinde artmış morbidite ve mortalite ile ilişkilidir. Bu retrospektif çalışmanın amacı bir üçüncü basamak tedavi merkezi olan hastanemizde EG insidansı, klinik karakteristikleri, ve tedavi sonuçlarını analiz etmektir.Gereç ve Yöntemler: Bu çalışmada Çanakkale Onsekiz Mart Üniversitesi Kadın Hastalıkları ve Doğum kliniğinde 2011ve 2015 yılları arasında EG tanısı alan 79 hasta retrospektif olarak incelendi. EG hastalarının tıbbi bilgileri hastane kayıt sisteminden alınarak bu çalışma için tasarlanmış formlara kayıt edildi.Bulgular: Beş yıllık sürede kliniğimizde gerçekleşen 1920 doğum içinde 79 EG vakası saptandı. EG insidansı %4.1 olarak kayıt edildi. Tanı alan hastaların en sık gözlendiği yaş aralığı 30-34 (34.2%) yıl idi. Abdominal ve/veya pelvik ağrı %56.9 ile en sık gözlenen şikayetti. Tanı sıklıkla ultrasonografik incelemeler ve seri ?hCG ölçümleri ile konuldu. Tıbbi ve cerrahi yöntemler en sık başvurulan tedavi şekilleri idi.EG hastalarında mortalite izlenmedi.Sonuç: EG belirgin morbidite ve mortalite ile seyreden ciddi bir sağlık sorunu olmaya devam etmektedir. Ciddi komplikasyonların önlenmesi için erken ve uygun tedavi verilmesi son derece önemlidir. Bununla birlikte EG'den korunma ve erken tanı, tüplerin korunması ve cerrahi ihtiyacının azaltılması açısından özel bir önem taşımaktadır.
  • [ X ]
    Öğe
    [Evaluation of anti-Toxoplasma gondii antibody distribution and risk factors among pregnant women admitted to obstetrics polyclinic of Canakkale Onsekiz Mart University Hospital].
    (2014) Gencer, Meryem; Cevizci, Sibel; Saçar, Suzan; Vural, Ahmet; Cakir Güngör, Ayşe Nur; Uysal, Ahmet; Hacivelio?lu, Servet Özden
    In this study, we aimed to investigate Toxoplasma gondii seroprevalence and risk factors in pregnant women. A total of 196 patients, admitted to the clinic in the first trimester and with ongoing pregnancy follow-up of between May 2012 and January 2013, were included in the study. Toxoplasma IgG and IgM antibodies were detected by ELISA test in blood samples obtained from patients during routine screening. SPSS statistical software, version 19.0 was used to analyze the data. Descriptive statistics were used to present the data, percentage, mean, and standard deviation. Chi-square test was used for categorical variables. p-value for statistical significance was defined as p<0.05. The mean age was 29.07±5.3 years in our study group. Anti-Toxoplasma IgG and IgM antibodies were found in 28.8% and 2.7%, respectively; 58.9% of pregnant women in the study reported that they had done at least one risky behavior during their pregnancy. However, there was no significant association between T. gondii IgG antibody positivity and risk factors, such as pregnancy, feeding animals in the past years, and consumption of raw food products (p>0.05). We found that Toxoplasma IgG antibody seropositivity (28.8%) was similar to that found in the other studies from western Turkey.
  • [ X ]
    Öğe
    Evaluation of surface ECG changes in pregnant women with gestational diabetes mellitus
    (Acta Medica Mediterranea, 2014) Gencer, Meryem; Gazi, Emine; Temiz, Ahmet; Hacivelio?lu, Servet; Güngör, Ayşe çakir; Barutçu, Ahmet; Altun, Burak
    Objective: Gestational diabetes mellitus (GDM) has an increased risk of maternal and fetal complications. Increased maternal cardiac risk is one of the most important complications. QT dispersion and Tp-e duration are findings of surface electrocardiogram (ECG) and they are used an index of inhomogeneity in ventricular electrical activity, and prolongation of QT dispersion is related to increased incidence of ventricular arrhythmias. In this study, we aimed to investigate QT dispersion, Tp-e interval and Tp-e/QT ratio in pregnant women with GDM and emphasize the increased cardiac risk and the importance of GDM screening Methods: Thirty pregnant women with GDM (mean age 27.3±6.1 years) and 23 normal pregnant women (30.2±5.4 years) were included in the study. A 12-lead surface electrocardiogram was used to evaluate QT and Tp-e durations for all participants. All QT intervals were corrected for heart rate using *1*?ş q L"2K, NBazett's formula. QT dispersion was defined as the difference between the maximum corrected QT and minimum corrected QT duration. Student's t test or Mann-Whitney U was used to compare groups. The results were evaluated at the p<0.05 significance level. Results: Mean age, body mass index, blood pressure, heart rate and gestational week of pregnancy were similar between the two groups. QT dispersion (54±13 msc vs. 44±12 msc, p=0.006), Tp-e (81±7 msc vs. 76±8msc, p=0.013) and corrected Tp-e (102.4±9.7msc vs. 96.5±8.2msc, p=0.038) were significantly longer in pregnant women with GDM. The Tp-e/QT corrected ratio was found to be higher in GDM patients (0.19±0.01 vs. 0.18±0.02, p=0.040). Conclusion: Our results suggest that QT dispersion, Tp-e interval and Tp-e/QTc ratio are increased in pregnant women with GDM compared to non-diabetic pregnant women. For this reason we suggest GDM screening for all healthy pregnant women and evaluation the long-term cardiac risks.
  • Küçük Resim
    Öğe
    Fetal anöploidi açısından yüksek riskli gebeliklerin QF-PCR ile analizi
    (Çanakkale Onsekiz Mart Üniversitesi, 2013-01) Güngör, Ayşe Nur Çakır; Hacıvelioğlu, Servet; Uludağ, Ahmet; Gencer, Meryem; Uysal, Ahmet; Atik, Sinem; Coşar, Emine; Sılan, Fatma; Özdemir, Öztürk
    [No Abstract Available]
  • [ X ]
    Öğe
    Is there an advantage of three dimensional computed tomography scanning over plain abdominal radiograph in the detection of retained needles in the abdomen?
    (Elsevier Science Bv, 2013) Hacivelioglu, Servet; Karatag, Ozan; Gungor, Aysenur Cakir; Gencer, Meryem; Kosar, Sule; Kizildag, Betul; Yildiz, Yavuz
    [Anstract Not Available]
  • [ X ]
    Öğe
    Is there any relationship between adverse pregnancy outcome and first trimester nuchal translucency measurements in normal karyotype fetuses?
    (Informa Healthcare, 2015) Uysal, Fatma; Cosar, Emine; Yucesoy, Kaya; Gencer, Meryem; Cevizci, Sibel; Gungor, Aysenur; Hacivelioglu, Servet
    Aim: This study aims to research whether there is a relationship between first trimester nuchal translucency (NT) measurements and pregnancy complications such as gestational diabetes mellitus (GDM), gestational hypertension (GHT), intrauterine growth restriction (IUGR) and oligohydramnios. Method: This study included 225 singleton pregnancies attending Canakkale Onsekiz Mart University Obstetrics and Gynecology clinic for all monitoring and examinations, and gave birth at our clinic between January 2011 and December 2012. Data sources were clinical records and the hospital's automation system, and the study was planned as retrospective cohort. NT measurement was made between 10 weeks 3 days and 13 weeks 6 days gestation. For data analysis, the chi-square, Mann-Whitney U test and Spearman correlation were used. Results: Of pregnancies, in the study, 5 (2.2%) developed GDM, 6 (2.6%) developed GHT, 2 (0.89%) developed IUGR and 10 (4.4%) developed oligohydramnios. There was no correlation identified between NT measurements and development of GDM, GHT, IUGR and oligohydramnios. Conclusion: There was no relationship found between first trimester NT measurements and complications that could develop in pregnancy. For the first time in the literature, NT and oligohydramnios were studied and no relationship was observed.
  • [ X ]
    Öğe
    Is There Any Relationship Between Platelet Functions, Red Cell Distribution Width and Recurrent Pregnancy Loss?
    (Derman Medical Publ, 2015) Uysal, Ahmet; Incebiyik, Adnan; Hacivelioglu, Servet; Gencer, Meryem; Gungor, Aysenur; Cosar, Emine
    Aim: Recurrent pregnancy loss (RPL) affects 1% pregnancies and its etiology is multi-factorial. Hypercoagulability might result in recurrent abortions; anticoagulant therapy could potentially increase the live-birth rate in subsequent pregnancies in women with unexplained recurrent abortions. Mean platelet volume (MPV) and platelet distribution width (PDW), are a parameter of platelet functions and may be a marker for increased platelet aggregability. In this study we aimed to determine whether MPV, PDW and red cell distribution width (RDW) values differ between patients with RPL and in healthy participants. Material and Method: A total of 50 RPL patients and 49 age matched healthy women were enrolled into the study. For all subjects following tests were performed: Hemoglobin, hematocrit, white blood cells counts (WBC), MPV, PDW, platelet count, RDW and thyroid stimulating hormone (TSH). Results: Compared with healthy controls there were no statistically differences in MPV and PDW between (p > 0.05, respectively) in women with RPL. However, RDW was significantly lower in patients with RPL than in group with control (p = 0.023,). Discussion: It was first shown in the literature that patients with RPL have no significance MPV and PDW than control subjects. However RDW levels were found that it was significantly related to recurrent pregnancy loss.
  • [ X ]
    Öğe
    Kadınların hayatındaki başka bir dönem: Menopoz ve menopozun yaşam kalitesine etkisi
    (2014) Uludağ, Ayşegül; Çakır, Ayşe Nur Güngör; Gencer, Meryem; Şahin, Erkan Melih; Coşar, Emine
    Amaç: Çalışmada menopoz öncesi ve menopoz dönemindeki kadınlarda menopozla ilişkili ortaya çıkan semptomların şiddeti veyaşam kalitesine etkisinin belirlenmesi amaçlandı.Yöntem: Kesitsel tanımlayıcı desendeki bu çalışmaya Kadın Hastalıkları ve Doğum ve Aile Hekimliği polikliniklerine başvuran 40-65yaş arasındaki 300 kadın alındı. Katılımcılara sosyo-demografik bilgileri içeren bir anket formunun yanı sıra, Menopoz İlişkili SemptomÖlçeği (MRS) ve SF-36 Yaşam Kalitesi Ölçeği uygulandı. Kadınlar,STRAW sınıflamasına göre menopoz öncesi ve menopoz dönemiolarak iki grup halinde değerlendirildi.Bulgular: Çalışmaya menopoz öncesi dönemde 57 (%19.0) ve menopozda 243 (%81.0) kadın katıldı. Yaş ortalaması 53.7±6.1 olankatılımcıların menopoza girme yaşı ortalaması 47.7± 4.5 idi. Menopoz öncesi dönemdeki katılımcılar (17.7±10.0) ile menopoz dönemindekilerin (16.0±8.7) MRS toplam puan ortalamaları arasında anlamlı bir fark yoktu (p>0.05). Menopoz öncesi ve menopoz dönemindeki kadınların SF-36 yaşam kalitesi skorları arasında da anlamlıbir fark saptanmadı (p>0.05). Katılımcıların MRS skorlarıyla yaşamkalitesi rol güçlüğü fiziksel (rho=-0.407; p<0.001) ve rol güçlüğüemosyonel (rho=-0.378; p<0.001) skorları arasında orta derecedeters yönde bir ilişki vardı. Ağrı (rho=0,223; p=0,001) ve genel sağlıkskorlarıyla (rho=0.152; p=0.039) doğrusal yönde zayıf; fiziksel fonksiyon (rho=-0.313; p<0.001), mental sağlık (rho=-0.288; p<0.001)ve sosyal fonksiyon (rho=-0.171; p=0.013) skorlarıyla ters yönde zayıf ilişkiler bulunmaktaydı.Sonuç: Kadınların menopoz öncesinde menopozla ilişkili psikolojik semptomları öne çıkmış olsa da menopoz dönemi ile arasındabir fark saptanmamıştır. Yaşam kalitesi de menopoz öncesi ve menopoz döneminde farklılık göstermemektedir. Menopozileilişkiliyakınmaların şiddeti arttıkça fiziksel ve emosyonel rol güçlüğü yaşam kalitesi skorlarıazalmaktadır.
  • [ X ]
    Öğe
    Men's Perspectives on Family Planning and Their Knowledge on Reproductive Health
    (Derman Medical Publ, 2014) Gungor, Ayse Nur Cakir; Uludag, Aysegul; Hacivelioglu, Servet; Gencer, Meryem; Ors, Polat; Yucesoy, Kaya; Uysal, Ahmet
    Aim: Many training programs for females about contraception have been developed. In this study, we aimed to investigate the perspectives of males on contraception and their knowledge on reproductive health. Material and Method: Husbands of pregnant women who presented in our obstetric clinic were invited to complete a questionnaire. Results: A total of 178 men answered our questionnaire. Among their wives, 11.1% (17/153) terminated their at least one unintended pregnancy. 142 of them (79.8%) knew about modern contraceptive methods, and 104 (58.4%) of them used at least one of these methods. Condoms were perceived as the best contraceptive method for 46.1% (35/76) because of their easiness to use and cheapness, and 41.7% (25/60) of the participants stated that they would like to use condom from then on. 55.6% (40/72) stated that they would never use oral contraceptives because of their possible side effects on their wives. 20 of the questions addressed to the participants were about reproductive health. The participants answered approximately 70% of all questions correctly. The correct answering rate for every question ranged between 39.6% and 96.1%. Discussion: In our study, we investigated attitudes and knowledge about contraception and reproductive health among men who were married and fertile. The findings from this study can provide a foundation for further education programs for men in these areas.
  • Küçük Resim
    Öğe
    Onsekiz haftalık spontan olarak sonlanan ve QF-PCR ile saptanan triploidik fetus: olgu sunumu
    (Çanakkale Onsekiz Mart Üniversitesi, 2013-03) Yalçıntepe, Sinem; Gencer, Meryem; Uludağ, Ahmet; Güngör, Ayşe Nur Çakır; Kumcular, Tuncer; Coşar, Emine; Sılan, Fatma; Özdemir, Öztürk
    [No Abstract Available]
  • [ X ]
    Öğe
    Outpatient screning results of pap smear
    (2014) Korkmaz, Fatma; Gencer, Meryem
    The purpose of this study is to determine the ratio of cervical intra-epithelial neoplasia and to evaluate the results of cervical smear collected from women who are examined at our outpatient polyclinic of gynecology and obstetrics department. Cervical smear results, evaluated with respect to Bethesda system, of 3813 women who are examined at outpatient polyclinic of gynecology and obstetrics department of İstanbul Beykoz State Hospital between July and November in 2013, are analyzed retrospectively. This study covered 3813 events. %99 cervical smears are satisfying while %1 of them are not. Epithelial cell anomaly is detected at 73 of satisfying cervical smears (%1.93). Also, 37(%1) atypical squamous cells of undetermined signifiance (ASC-US), 4 (%0.1) atypical squamous cells suggestive of high grade (HSIL), 19 (%0.5) low grade squamous intraepithelial lesion (LSIL), 6 (%0.15) high grade squamous intraepithelial lesion (HSIL), 2 (%0.05) squamous cell carcinoma (SCC), 3 (%0.08) atypical glandular cells (AGC), and 2 (%0.05) adenocarcinoma (ACC) are determined. At the satisfying cervical smears that are negative in terms of intraepithelial lesions and malignancy, the most frequent inflammation is 2330 (%62), normally 550 (%14), infection 469 (%12), and atrophy 366 (%10) is observed. In this study, the ratio of total cervical epithelial anomaly is observed as %1.93. However, in the future we can reach much more detailed data by applying the process of national cancer screening programs in Turkey.
  • [ X ]
    Öğe
    Plasma levels of Nesfatin-1 in patients with polycystic ovary sydrome
    (Acta Medica Mediterranea, 2014) Binneto?lu, Emine; Erba?, Gökhan; Gencer, Meryem; Turkön, Hakan; Aşik, Mehmet; Güneş, Fahri; Şen, Hacer
    Introduction: Polycycstic ovary syndrome (PCOS) is an important disorder in women of reproductive age which is characterised with menstrual dysfunction, anovulation and hyperandrogenism. 5-10% of the female population affected by this syndrome. Nesfatin-1 is a new anorexigenic hormone which is expressed from several regions of hypothalamus and peripheral tissues. Nesfatin-1 is related with obesity, insulin resistance and appetite. We aimed to evaluated the nesfatin-1 levels in patients with PCOS. Material and methods: Sixty-five patients (37 patients with PCOS and 28 healthy control subjects) were enrolled in the study. We included newly diagnosed patients with PCOS in our study. Diagnosis of PCOS was based on the 2003 ESHRE/ASRM diagnostic criteria. Results: The patients with PCOS and controls were similar in terms of mean age body mass index (BMI), waist/hip (W/H) ratio and homeostasis model assessment-insulin resistance (HOMA-IR) index. Plasma Nesfatin-1 levels were similar between groups. There was no correlation between plasma Nesfatin-1 levels and other parameters. Conclusion: In conclusion nesfatin-1 may be play important role in glucose metabolism and insulin resistance. In this study due to the absence of insulin resistance in PCOS patients, levels of Nesfatin -1 were similar with control group. Nesfatin levels were associated with glucose metabolism, but further studies are needed in this regard.