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    A giant chorioangioma of the placenta with favorable outcome: a rare case presentation with literature review
    (2016) Beyazit, Fatma; Göret, Ceren Canbey; Pek, Eren; Gencer, Meryem
    Chorioangioma, or hemangioma of the placenta, is the most frequent non-trophoblastic tumor of the placenta consisting of blood vessels and stroma. A great proportion of these tumors are small and well delineated within the placental parenchyma and have no or minimal adverse impact on the fetus. Unfortunately, large tumor size is linked to serious complications such as fetal anemia, hydrops and intrauterine death. This is probably because of arteriovenous shunts leading to progressive heart failure of the fetus. With the increasing rates of antenatal screenings with ultrasonography, prenatal diagnosis of these tumors is widely achieved. Here we report a case of giant placental chorioangioma diagnosed in the second trimester of pregnancy. The size of the tumor minimally increased during follow-up and at term, uncomplicated labor was achieved. Macroscopic and histologic examination confirmed the diagnosis
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    Öğe
    Nadir Bir Olgu Sunumu: Senkron Pankreatik Duktal Adenokarsinom ve Tiroid Medüller Karsinom
    (2017) Göret, Ceren Canbey; Özkan, Ömer Faruk; Akgün, Mehmet Yılmaz
    Günümüzde ilerleyen tedavi yöntemleriyle kanserli hastaların sağ kalım süresi uzamıştır. Bu nedenle ikincil primer tümör görülme sıklığında artış gözlenmektedir. Hastanemize başvuran 52 yaşındaki erkek hastada senkron pankreas duktal adenokarsinomu ve tiroid medüller karsinom tespit edildi. Bu iki tümör birlikteliği daha önce bildirilmediğinden literatürde paylaşmayı amaçladık.
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    Öğe
    The activity of topical coenzyme Q10 (Ubiquinol) in burned rats: Results from an experimental study
    (Yuzuncu Yil Universitesi Tip Fakultesi, 2019) Göret, Ceren Canbey; Kiraz, Aslı; Göret, Nuri Emrah; Kılıç, Sevilay Oğuz; Özkan, Ömer Faruk; Karaayvaz, Muammer
    The objective of this study was to investigate the effectiveness of topically applied coenzyme Q10 (CoQ10) (ubiquinol) for wound healing in rats with experimentally induced burn injuries. A total of 27 rats were divided into three groups, and administered general anesthesia. No further intervention was performed for Group 1 (Control). Hot water (95°C) was applied to rats in Groups 2 and 3 for 10 seconds. The rats in Group 2 received silver sulfadiazine, whereas those in Group 3 received topical CoQ10. Biopsy samples were obtained at days 3 and 10. In the group treated with CoQ10 (Group 3), there was no statistically significant difference among between Days 3 and 10 in terms of inflammation and epidermal/vascular/collagen damage. In terms of edema, there was a statistically significant distinction among the CoQ10 group (Group 3) at Day 10 and the silver sulfadiazine group (Group 2) at Day 3. In terms of oxygen radicals, there was a statistically meaningful difference among the CoQ10 group and the silver sulfadiazine group at Day 10. This investigation did not demonstrate a beneficial role of treatment with CoQ10 for the healing of burn wounds for most parameters. But in the long term (10 day); immunohistochemical analysis performed to determine edema and oxidative stress showed that treatment with CoQ10 reduced the levels of oxygen radicals in biopsies. The limitation of our study is that the duration is limited to 10 days. For this reason longer term studies were required. © 2019, Yuzuncu Yil Universitesi Tip Fakultesi. All Rights Reserved.