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    Can a familial history of migraine and motion sickness be used in the diagnosis of childhood migraine?
    (Elsevier, 2025) Cokyaman, Turgay; Erdem, Ulgen Ozcan
    Objective: Childhood migraine is a recurrent neurobiological complex disease and caused by multiple genetic and environmental factors. In this study, the clinical relevance of ICHD-3 diagnostic criteria, familial history of migraine and motion sickness was investigated. Methods: This study was conducted on children aged 10-18 years, who were randomly selected from 22 middle and 26 high schools. The survey, prepared in Turkish, asked about headache characteristics (ICHD-3 diagnostic criteria: 7 items), familial history of migraine, and presence of motion sickness (2 items). Results: According to data from the survey, 4 main factors emerged in the exploratory factor analysis. Photophobia, pain attack duration >= 1 h, headache attacks more than 4 times, familial history of migraine in factor-1, vomiting and nausea in factor-2, pulsatile pain and forehead and bitemporal localization in factor-3, avoidance routine physical activities and motion sickness in factor-4 are collected. Conclusion: Migraine, in which strong genetic pieces of evidence have been uncovered is a multifactorial brain disease. Moreover, the intense connections between the trigeminal system and vestibular nuclei demonstrated in the current literature reveal that the relationship between motion sickness and migraine cannot be ignored. Therefore, a positive familial history and motion sickness in childhood migraine are important additional diagnostic clues in addition to ICHD-3.
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    Use of ICHD-3rd diagnostic criteria in determining the prevalence of migraine in childhood; school-based cross-sectional questionnaire study
    (Taylor & Francis Ltd, 2024) Cokyaman, Turgay; Erdem, Ulgen Ozcan
    ObjectiveThis study aimed to determine the relationship between migraine prevalence and its diagnostic features in school children.MethodsThis study was conducted on children aged 10-18 year who were randomly selected from 22 middle and 26 high schools. Questionnaires were prepared in Turkish with demographic (9 items) and headache characteristics (ICHD-3rd-based headache screening questionnaire, 11 items).ResultsA total of 1450 surveys were properly filled out. Female/male ratio was 798/652 (55%divided by 45%) and the mean age was 14.4 years +/- 2.1. 96.4% of the population in this study. According to the criteria of headache attack number (>= 4 attacks), character (pulsatile) and duration (>= 1 h), the prevalence of migraine in the studied population was 23.1%.ConclusionPopulation-based studies are important because they provide information on diagnosing migraine, which is a public health priority in childhood, and contribute to creating the world migraine atlas. Although additional diagnostic clues are needed to determine the prevalence of migraine in childhood, we still widely use headache screening questionnaires based on ICHD-3rd.