Yazar "Ercan, E." seçeneğine göre listele

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    Adiponectin levels is strongly associated with NT-Brain Natriuretic Peptide levels, LV diameters and ejection fraction in patients with heart failure
    (Oxford Univ Press, 2009) Turk, U. O.; Alioglu, E.; Kirilmaz, B.; Tamer, G. S.; Tengiz, I.; Tuzun, N.; Ercan, E.
    [Anstract Not Available]
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    Changes in kidney tissue and effects of erythropoietin after acute heart failure
    (Taylor & Francis Ltd, 2018) Bagla, A. Guven; Gulen, M. Ickin; Ercan, F.; Asgun, F.; Ercan, E.; Bakar, C.
    Impairment of cardiac function causes renal damage. Renal failure after heart failure is attributed to hemodynamic derangement including reduced renal perfusion and increased venous pressure. One mechanism involves apoptosis and is defined as cardiorenal syndrome type 1. Erythropoietin (EPO) is a cytokine that induces erythropoiesis under hypoxic conditions. Hypoxia inducible factor 1 alpha (HIF-1 alpha) plays a regulatory role in cellular response to hypoxia. Protective effects of EPO on heart, kidney and nervous system are unrelated to red blood cell production. We investigated early changes in and effects of EPO on renal tissues of rats with myocardial infarction by morphology and immunohistochemistry. Coronary artery ligation was used to induce myocardial infarction in Wistar rats. Group 1 comprised sham operated rats; groups 2, 3 and 4 included rats after coronary artery ligation that were sacrificed 6 h after ligation and that were treated with saline, 5,000 U/kg EPO or 10,000 U/kg EPO, respectively; group 5 included rats sacrificed 1 h after ligation. Group 2 showed increased renal tubule damage. Significantly less tubule damage was observed in EPO treated groups. EPO and EPO receptor (EPO-R) immunostaining intensities increased slightly for group 5 and became more intense for group 2. EPO and EPO-R immunostaining was observed in the interstitial area, glomerular cells and tubule epithelial cells of EPO treated groups. HIF-1 immunostaining was observed in collecting tubules in the medulla only in group 2. Caspase-3 immunostaining is an indicator of apoptosis. Caspase-3 staining intensity decreased in renal medulla of EPO treated groups. EPO treatment may exert a protective effect on the renal tissues of patients with cardiorenal syndrome.
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    Decreased left ventricular torsion in patients with isolated mitral stenosis
    (Urban & Vogel, 2015) Kirilmaz, B.; Asgun, F.; Saygi, S.; Ercan, E.
    Left ventricular (LV) torsion is a sensitive indicator of myocardial contractility and cardiac structure, and has recently been recognized as a sensitive indicator of cardiac performance. The aim of our study was to assess the effect of isolated mitral stenosis on LV torsion. We enrolled 19 patients with isolated mitral stenosis and 19 age- and gender-matched healthy subjects in the study. All patients had a normal sinus rhythm. All study subjects underwent two-dimensional echocardiography. Basal and apical LV rotations and LV torsion were evaluated using speckle-tracking echocardiography. Demographic characteristics, basic echocardiographic measures of LV ejection fraction, LV wall thickness, and LV mass index were similar between the two groups. The degrees of LV torsion (11.3 +/- 4.7, 15.4 +/- 4.9A degrees, p=0.014) and LV basal rotation (-aEuro parts per thousand 3.7 A +/- 1.9, -aEuro parts per thousand 6.5 A +/- 2.1A degrees, p < 0.001) were significantly decreased in the mitral stenosis group. There was a moderate positive correlation between mitral valve area and LV torsion (r=0.531, p=0.019). We showed significant reductions in LV torsion and LV basal rotation in patients with mitral valve stenosis. Structural and anatomical changes occurring during the progression of mitral stenosis may be responsible for these impaired movements.
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    Effect of N-acetylcysteine on serum creatinine and cystatin C levels after cardiovascular procedures
    (Oxford Univ Press, 2009) Alioglu, E.; Turk, U.; Ercan, E.; Tamer, G. S.; Tengiz, I.; Kirilmaz, B.; Saygi, S.
    [Anstract Not Available]
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    Myocardial performance index in sprinters and endurance athletes
    (Oxford Univ Press, 2009) Tuzun, N.; Ergun, M.; Alioglu, E.; Turk, U. O.; Tengiz, I.; Saygi, S.; Ercan, E.
    [Anstract Not Available]
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    No additional benefit from higher dose erythropoietin to reduce infarct size after coronary artery ligation in wistar rats
    (Oxford Univ Press, 2010) Ercan, E.; Guven, A.; Asgun, F.; Ickin, M.; Ercan, F.; Kaplan, A.; Yavuz, O.
    [Anstract Not Available]
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    The influence of alpha-adducin gene polymorphism on response of blood pressure to exercise in patients with hypertension
    (Oxford Univ Press, 2008) Alioglu, E.; Ercan, E.; Tengiz, I.; Turk, U.; Ergun, M.; Akgoz, S.; Islegen, C.
    [Anstract Not Available]