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    An Evaluation of Provoked Vulvodynia, Pelvic Floor Muscles and Sexual Functions in Female Patients with Fibromyalgia Syndrome
    (Galenos Yayincilik, 2017) Resorlu, Hatice; Beyazit, Fatma; Doner, Davut; Oymak, Sibel; Zateri, Coskun
    Objective: The aim of our study is to investigate the genital origin of pain, particularly provoked vulvodynia (PVD) in female patients with Fibromyalgia syndrome (FMS), to reveal the relationship between PVD and pelvic floor muscle functions and to evaluate patients' sexual functions. Materials and Methods: Twenty four female patients who were diagnosed with FMS and who had not yet been treated, sexually active and 24 control cases were included to study. Severity of dyspareunia and dysmenorrhea was evaluated with a visual analogue scale, PVD was assessed using the cotton swab exam of vulva and sexual functions were evaluated with using the Female Sexual Function Index (FSFI). Additionally, pelvic floor muscles were graded using Brink scoring. Results: The severity means of menstrual term pain and dyspareunia severity were significantly higher in the patients than the control group (p=0.003, p=0.006). Significant differences were observed between the patient and control group in terms of vulvar pain in cotton swab exam and total Brink scores (both p<0.001). FSFI score was lower in the patient group than in the control group (p=0.001). A powerful correlation in the negative direction was determined between the result of cotton swab exam and Brink score (p<0.001, r=-0.575). Conclusion: The result of our study showed that dysmenorrhea, dyspareunia and PVD were significantly high in the FMS patients than in the control group. Pelvic floor muscle functions were affected in the FMS patients, and PVD was closely associated with the pelvic floor muscle functions.
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    An Evaluation of Sexual Functions and Marital Adjustment in Female Patients with Fibromyalgia Syndrome
    (Galenos Yayincilik, 2019) Doner, Davut; Resorlu, Hatice; Zateri, Coskun; Sahin, Basak; Ertekin, Hulya; Oymak, Sibel
    Objective: The purpose of this study was to investigate sexual functions and marital adjustment which are neglected issue in married female patients diagnosed with Fibromyalgia syndrome (FMS) and to reveal the factors affecting these. Materials and Methods: Sexually active, 47 married females who diagnosed with FMS and 50 healthy volunteers in a similar age group were included in the study. Beck anxiety inventory, beck depression inventory, female sexual function index (FSFI) and dyadic adjustment scale (DAS) evaluations were also performed for both groups. In the patient group, the severity of pain was evaluated by the visual analogue scale and functional impairment due to the disease was assessed by the fibromyalgia impact questionnaire (FIQ). Results: No significant difference was determined between the two groups in terms of socio-demographic features. FSFI and DAS total scores were significantly lower in the patient group compared to the controls (p<0.001, p=0.028, respectively). Low DAS scores were determined in patients with low FSFI scores (p=0.003, r=+0.043). Neither FSFI nor DAS scores have exhibited correlation with duration of disease and FIQ scores. Depression was correlated with both FSFI and DAS (p<0.001, r=-0.569; p<0.001, r=-0.546, respectively). Conclusion: In this study, sexual functions and marital adjustment were adversely affected in patients with FMS. This effect was found closely related to depression. However, there was no relationship determined between duration of the disease, the severity of pain and the functional impact.
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    Are inflammatory bowel disease patients aware of Achilles tendonitis?
    (Oxford Univ Press, 2014) Akbal, Ayla; Gokmen, Ferhat; Doner, Davut; Uysal, Fatma
    [Anstract Not Available]
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    Incidentally Diagnosed Osteopoikilosis: A Case Report
    (Galenos Yayincilik, 2017) Resorlu, Mustafa; Karatag, Ozan; Toprak, Canan Akgun; Doner, Davut
    Osteopoikilosis is a rare bone dysplasia. Patients are generally asymptomatic and are frequently identified during radiological imaging by coincidence. The epiphysis and metaphysis of the long bones, the phalanges and pelvic bones are the localizations which frequently involved. It appears as oval or round, homogeneous, symmetrical, uniform, radio-opacities. Osteoblastic metastases, mastocytosis, tuberous sclerosis and Paget's disease should be considered in differential diagnosis.
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    Increased Levels of Serum Ischemia Modified Albumin in Patients with Ankylosing Spondylitis
    (Clin Lab Publ, 2016) Turkon, Hakan; Gokmen, Ferhat; Cakir, Dilek Ulker; Sehitoglu, Muserref Hilal; Resorlu, Hatice; Doner, Davut; Essizoglu, Ertan
    Background: The aim of the study was to investigate oxidant/antioxidant status by determining serum ischemia-modified albumin (IMA) levels with oxidative/antioxidant parameters in patients with ankylosing spondylitis (AS) compared to the controls. Methods: The serum concentrations of IMA, IMA/albumin ratio (IMAR), malondialdehyde (MDA), total oxidant status (TOS), oxidative stress index (OSI), superoxide dismutase (SOD), glutathione peroxidase (GPx), and total antioxidant capacity (TAC) were measured in 40 AS patients and 35 healthy controls. Results: Mean serum IMA, IMAR, MDA, TOS, and OSI levels were increased in patients with AS when compared to the control group (p < 0.05 for all). Serum levels of SOD and GPx were significantly lower in the patient group than in the healthy subjects (p < 0.001 for both). Serum TAC levels were decreased in patients with AS compared to the controls but the statistical difference was not significant. Serum IMA levels were found to be positively correlated with BASDAI, BASFI, BASMI, and ASDAS-CRP (r = 0.356, r = 0.370, r = 0.412, r = 0.353, respectively, and p < 0.05 for all). IMAR values showed significant correlations with BASFI, BASMI, and ASDAS-CRP (r = 0.351, p = 0.026; r = 0.400, p = 0.010; and r = 0.379, p = 0.016, respectively). Conclusions: Depletion in antioxidant systems and overproduction of free radicals leading to formation of the oxidative stress may play a role in the development of AS. Increased levels of IMA might provide important contributions to the underlying oxidative stress in AS.
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    The relationship between chondromalacia patella, medial meniscal tear and medial periarticular bursitis in patients with osteoarthritis
    (Assoc Radiology & Oncology, 2017) Resorlu, Mustafa; Doner, Davut; Karatag, Ozan; Toprak, Canan Akgun
    Background. This study investigated the presence of bursitis in the medial compartment of the knee (pes anserine, semimembranosus-tibial collateral ligament, and medial collateral ligament bursa) in osteoarthritis, chondromalacia patella and medial meniscal tears. Patients and methods. Radiological findings of 100 patients undergoing magnetic resonance imaging with a preliminary diagnosis of knee pain were retrospectively evaluated by two radiologists. The first radiologist assessed all patients in terms of osteoarthritis, chondromalacia patella and medial meniscal tear. The second radiologist was blinded to these results and assessed the presence of bursitis in all patients. Results. Mild osteoarthritis (grade I and II) was determined in 55 patients and severe osteoarthritis (grade III and IV) in 45 cases. At retropatellar cartilage evaluation, 25 patients were assessed as normal, while 29 patients were diagnosed with mild chondromalacia patella (grade I and II) and 46 with severe chondromalacia patella (grade III and IV). Medial meniscus tear was determined in 51 patients. Severe osteoarthritis and chondromalacia patella were positively correlated with meniscal tear (p < 0.001 and p = 0.018, respectively). Significant correlation was observed between medial meniscal tear and bursitis in the medial compartment (p = 0.038). Presence of medial periarticular bursitis was positively correlated with severity of osteoarthritis but exhibited no correlation with chondromalacia patella (p = 0.023 and p = 0.479, respectively). Evaluation of lateral compartment bursae revealed lateral collateral ligament bursitis in 2 patients and iliotibial bursitis in 5 patients. Conclusions. We observed a greater prevalence of bursitis in the medial compartment of the knee in patients with severe osteoarthritis and medial meniscus tear.