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Öğe A Bibliometric Analysis Study of Global Academic Articles on Malaria and Contribution of Türkiye(Ordu University, 2024) Aydemir, Selahattin; Diril, Halit; Alkan, Sevil; Barlık, Fethi; Ekici, AbdurrahmanObjective: Malaria is a parasitic infection that has a significant negative influence on public health around the world, including Türkiye in recent years with the prevalence of imported cases. This study was conducted to provide a bibliometric analysis of publications on malaria in Türkiye and worldwide, and to determine Türkiye's current position in malaria research. Methods: This study was observational, descriptive, and retrospective designed study and utilized scientometric technique and scientific mapping. The research was conducted in the Web of Science online database. The MESH keywords (malaria OR plasmodium) were used. The title (TI) field and only Science Citation Index Expanded (SCI-E) index was used for the search queries. The following inclusion and exclusion criteria were applied: The studies published after the end of 2022 were excluded and only the articles were chosen according to the document type. Results: On the basis of the defined search, 31376 articles were extracted from the WoS database indexed in the SCI-E category, for the period 1970-2022. The earliest article was published in 1970 and the most of the articles were published in 2021 (n=1274). There was a growth in publications number since end of the 1970s. A total 469 countries contributed the malaria literature. The United States of America (USA) (32.07%), England (18.56%) and France (9.90%) were the leading countries on the malaria literature according to the published article numbers. Türkiye ranked in 71st. A total of 80 articles were retrieved according to search criteria. The articles were cited 1347 times totally and 17.75 times per article. The mean of H index was 18. The earliest articles were published in 1987. The number of articles limited but since 2005 never dropped below two articles per year. Conclusion: Scientific production from Türkiye is low. This topic can be improved by increasing both the financial support for and the involvement of researchers in national and international collaborative research projects.Öğe The Radio-protective effects of Caffeic Acid Phenethyl Ester and Thymoquinone in rats exposed to total head irradiation(Springer Wien, 2015) Cikman, Oztekin; Taysi, Seyithan; Gulsen, Murat Taner; Demir, Elif; Akan, Muslum; Diril, Halit; Kiraz, Hasan AliMany cancer patients treated with radiotherapy suffer severe side effects during and after their treatment. The aim of this study was to investigate the effects of irradiation and the addition of caffeic acid phenethyl ester (CAPE) and thymoquinone (TQ) on the oxidant/antioxidant system in the liver tissue of irradiated rats. A total of 40 Sprague-Dawley rats were divided into five groups to test the radioprotective effectiveness of thymoquinone and caffeic acid phenethyl ester administered by intraperitoneal injection. Appropriate control groups were also studied. While liver tissue total oxidant status, lipid hydroperoxide level, and oxidative stress index were significantly increased in the irradiated (IR) group, compared with other groups, total antioxidant status, sulfhydryl levels, and paraoxonase (PON) activity were significantly decreased. Ceruloplasmin activity in IR plus TQ and IR groups was higher than the control group. Arylesterase and PON activities in IR plus TQ- and IR plus CAPE-supplemented groups were lower than those of control groups. TQ and CAPE decrease oxidative stress markers and have antioxidant effects, which also augment antioxidant capacity in the liver tissue of irradiated rats.Öğe The Radioprotective Effect of Caffeic Acid Phenethyl Ester and Thymoquinone in Rats Exposed to Total Head Irradiation(Elsevier Science Inc, 2014) Cikman, Oztekin; Taysi, Seyithan; Gulsen, Murat Taner; Demir, Elif; Akan, Muslum; Diril, Halit; Kiraz, Hasan Ali[Anstract Not Available]Öğe The Radioprotective Effects of Caffeic Acid Phenethyl Ester and Thymoquinone against Oxidative and Nitrosative Stress in Liver Tissue of Rats Exposed to Total Head Irradiation(Elsevier Science Inc, 2014) Cikman, Oztekin; Taysi, Seyithan; Gulsen, Murat Taner; Demir, Elif; Akan, Muslum; Diril, Halit; Kiraz, Hasan Ali[Anstract Not Available]
