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    Comparison of CBCT radiation doses with conventional radiographs in TMJ imaging using Monte Carlo simulations
    (Springer Science and Business Media Deutschland GmbH, 2024) Deniz, Yeşim; Eren, Hakan; Sessiz, Rüya; Coşan Ata, Gamze
    Three-dimensional imaging methods are widely used for evaluation of bony changes of temporomandibular joint (TMJ). Besides, lateral and posterio-anterior TMJ projections in both closed- and open-jaw positions for each temporomandibular joint are used as two-dimensional diagnostic tools. The purpose of the present study was to compare effective and mean organ absorbed doses of plain radiography techniques with those of different modalities of cone beam computed tomography (CBCT) scanning of an adult’s temporomandibular joint. PCXMC 2.0 software was used to calculate mean organ and effective doses. A NewTom CBCT device (Newtom 5G XL; QR systems; Verona, Italy) was simulated at 360° rotation using a 6 × 6 cm2 FOV in standard and high-resolution modes. Lateral and posterio-anterior TMJ plain projections were simulated according to recommendations of the manufacturer of the Planmeca ProMax® 2D S3 device. Doses for both projections were simulated with Monte Carlo methods and the International Commission on radiological protection adult reference computational phantoms. The highest mean organ absorbed doses occurred in bone surfaces, salivary glands, and skull for posterio-anterior TMJ and lateral TMJ, and for CBCT scanning in all examinations. The effective doses of posterio-anterior and lateral TMJ plain radiographs were found to be higher than those of the Standard Mode-Eco Scan CBCT. Therefore, the lowest effective dose was calculated in Standard Mode-Eco Scan CBCT. It is concluded that NewTom 5G XL Standard Mode-Eco Scan CBCT can be used instead of plain radiographs (lateral and posterio-anterior TMJ) in temporomandibular joint imaging as it allows visualizing the three-dimensional structure of the temporomandibular joint as an advantage.
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    Comparison of Dental and Skeletal Age Estimating Methods in Children
    (University of Zagreb, 2023) Çelik Güler, Özge; Deniz, Yeşim; Arslan, Semiha
    Objectives: Estimating age is a crucial determinant of forensic science. Various methods have been used to estimate dental age (DA) and skeletal age (SA).The aim of the current study was to compare the Cameriere's DA method with the Cameriere's SA method in estimating CA in children. Materials and methods: A total of 216 radiographs of 130 females and 86 males (between 9 to 14.99 years of age) were evaluated in northwestern Turkey. DA was calculated on the panoramic images using Cam-eriere's open-apex method. SA was determined on the lateral cephalograms using the fourth cervi-cal vertebrae method by Cameriere. The DA, SA, and CA data were compared using a paired t-test and Wilcoxon test. Results: The mean CA of all groups was calculated as 12.96 +/- 0.30, the mean DA of 12.74 +/- 0.68 and the mean SA of 12.89 +/- 0.89. In males, the DA method presented an underestima-tion between ages of 14.00 and 14.99 (p<0.05) and an overestimation between ages 9.00 and 11.99 (p<0.05). In females, the DA method showed an underestimation in the 13.00-and 14.99-year-old age groups (p<0.05) and an overestimation in the 10.00-and 11.99-year-old age groups (p<0.05). The SA method revealed a significant underestimation in females between the ages of 13.00 and 14.99 and in males between the ages of 14.00 and 14.99 (p<0.05). Conclusions: The SA estimation method may provide more accurate results compared to the DA method with children of both sexes aged between 9.00 to 12.99 in the determination of CA.
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    Comparison of pediatric doses of cone beam computed tomography and panoramic radiography in three age groups
    (Novin Medical Radiation Institute, 2025) Eren, Hakan; Deniz, Yeşim; Ata, G.C.; Sessiz, Rüya
    Background: A wide variety of radiation dose values can occur in Cone Beam Computed Tomography (CBCT) devices with different field of view (FOV) sizes. Radiation dose of current CBCT devices have been considerably reduced. This study compared effective radiation doses and organ absorption doses obtained from panoramic and CBCT imaging at various FOV sizes in children aged five, ten, and fifteen years. Materials and Methods: To calculate the organ doses and effective doses, a dose calculation software PC-based Monte Carlo (PCXMC) 2.0 based on Monte-Carlo simulation was used for CBCT and panoramic exposures. Both absorbed and effective doses were calculated for the simulated phantoms of 5, 10 and 15 years old separately. Results: The organ doses of thyroid and salivary glands measured with 6*6 ECO Scan CBCT were found to be lower when compared with panoramic radiography organ doses. Panoramic radiography effective doses were lower than all other CBCT modes in all age groups. Conclusion: Although it is stated that this study does not have diagnostic data, it is thought that 6×6 ECO Scan Mode of Newtom CBCT can be chosen instead of panoramic radiography in children aged 5 years due to the dose differences. © 2025 Novin Medical Radiation Institute. All rights reserved.
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    Effects of direct therapeutic radiation on pulpal surface of root dentin: an in vitro study
    (Springer Science and Business Media Deutschland GmbH, 2023) Deniz, Yeşim; Işıktaş Acar, Ezgi; Çetin Genç, Çiğdem
    The aims of the study were to analyze the effects of therapeutic radiation on human root dentin samples from the aspect of possible alterations in crystallinity, micro-morphology, and composition. Fifty-six root dentin specimens were divided into seven groups (0, 10, 20, 30, 40, 50, and 60 Gy). Scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD) analyses were performed on pulpal surfaces of root dentin after being irradiated by 6MV photon energy. Mineral compositions, Ca/P, P/N, Ca/N ratios, and hydroxyapatite pikes were calculated. Some deuteriations on the dentin surface were observed in SEM images after 30 Gy and subsequent doses. One-way ANOVA revealed that there was no significant alteration in weight percentages of C, O, Mg, Ca, P, and N between groups. Radiation did not influence stoichiometric Ca/P, Ca/N, and P/N molar ratios. XRD analysis did not show a remarkable decline in hydroxyapatite pikes by the increasing doses. Radiotherapy changes the micromorphology of circumpulpal dentin but does not affect elemental composition and crystallinity.
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    Effects of high temperature on dental restorative materials for forensic purposes
    (Springer, 2021) Çarıkçıoglu, Burak; Misilli, Tuğba; Deniz, Yeşim; Aktaş, Çağatay
    This study aimed to observe the efects of high temperature on diferent restorative dental materials by detecting changes in their microstructural and elemental composition. Disk shaped samples (10 mm diameter, 2 mm depth) were prepared from 8 dental materials (compomer, glass carbomer, ormocer, giomer, zinc reinforced glass ionomer (GI), silver-alloy reinforced GI, zirconia reinforced GI, and conventional GI). Scanning electron microscopy/Energy dispersive X-ray spectroscopy (SEM/EDS) was used to characterize sample surface structures and elemental composition. The same samples were also analyzed using X-ray fuorescence (XRF) to determine the trace element content. Each sample was placed in a porcelain furnace and exposed to 900 °C for 30 min. Observations of macroscopic changes in samples after exposure high temperature were recorded. The microstructural changes in sample surfaces after incineration were detected by SEM. The elemental compositions obtained before and after the incineration were compared after repeating the XRF and EDS analyses. Dental materials demonstrated specifc macroscopic changes and microstructural deteriorations detected by SEM images after exposure to high temperature. While several changes occurred in the elemental content of materials in terms of amount, the original elemental composition was preserved. The ability to distinguish dental materials by elemental analyses has had an important impact on the identifcation process.
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    Effects of radiotherapeutic X-ray irradiation on cervical enamel
    (Taylor and Francis Ltd., 2021) Deniz, Yeşim; Aktaş, Çağatay; Misilli, Tuğba; Çarıkçıoğlu, Burak
    Purpose Therapeutic radiation used for head and neck cancers mainly affects the cervical region of the tooth. To better understand the impact of therapeutic radiation on tooth, we aimed to examine the crystallinity, micro-morphology, and elemental composition of the cervical inner enamel located adjacent to the dento-enamel junction. Materials and methods Ninety-one specimens obtained from 16 impacted third mandibular molars were randomly divided into seven groups (0, 10, 20, 30, 40, 50, and 60 Gy irradiation groups). Energy-dispersive X-ray spectroscopy (EDX) and scanning electron microscopy (SEM) were performed after the irradiation by 6 MV photon energy. The X-ray diffraction (XRD) were conducted in every group before and after irradiation. Elemental compositions, and Ca/P, P/N, Ca/N atomic ratios were subjected to the Shapiro-Wilk normality test. All of the elements except Mg showed a normal distribution and were compared by the one-way ANOVA. The non-normally distributed Mg data and Ca/P, P/N, and Ca/N ratios were compared by the Kruskal-Wallis test. Results The results showed that widening in the interprismatic spaces were observed in the experimental groups subjected to 30 Gy and the following increased doses. In addition, there were no significant differences in C, O, Ca, P, N percentages between irradiated and non-irradiated groups (p > .05). An increase in atomic ratio of the Mg was detected after samples conducted by 60 Gy radiation dose (p < .05). The stoichiometric Ca/P, Ca/N, and P/N atomic ratios did not change by irradiation (p > .05). The XRD peaks of the inner enamel crystalline phase showed a slight decline in the 60 Gy radiation dose group. Conclusion Radiation effects begin to be seen after 30 Gy radiation dose groups. The widen interprismatic spaces seen obviously in 50 Gy and 60 Gy dose groups. Besides Mg ratio showed an increase in the 60 Gy dose group. But it should be thought that radiation caries is a multi-factorial disease that is in collaboration with various radiation-induced side effects.
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    Evaluation of student satisfaction for compulsory distance education in the faculty of dentistry: A survey study
    (Selcuk University, 2022) Deniz, Yeşim; Genç, Çiğdem Çetin; Genç, Celal; Baran, İlgi; Değirmenci, Alpin
    Background The educational process in all universities has been strongly affected by the SARSCoV-2 (COVID-19) epidemic. In line with the measures to prevent the spread of the virus, the ongoing courses at Çanakkale Onsekiz Mart University, Faculty of Dentistry were transferred from face-to-face education to the online distance education method in the spring term of 2020. The aim of this study is to evaluate the satisfaction of students about the emergency distance education method. Material and Methods 1st, 2nd and 3rd grade students filled out an online questionnaire examining the used materials and communication tools, teacher-student interaction, environment design, attitudes towards e-course, the content of the course and the teaching process in January 2021, 2 semesters after the implementation of the distance education method. Data were evaluated with descriptive statistics. Chi-square and Fisher Exact tests were used for comparisons between classes and genders. The statistical significance limit was set as 0.05. Results A total of 189 students (116 female, 73 male students) participated in the survey. It was observed that 45.9 % of all students participating in the survey were not satisfied with distance education, and 65.07 % of them had less motivation to learn in distance education compared to traditional education. It was observed that the teacher-student interaction of the first grade students was lower than the 2nd and 3rd grade students (p<0.05). Conclusion It is thought that distance education methods should be developed in the light of the data of the study carried out on students
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    Evaluation of the differences in the localization of the lingula mandibulae according to pubertal development in children: A new anthropological and forensic approach
    (Elsevier Ltd, 2024) Eren, Hakan; Sezer, Berkant; Deniz, Yeşim
    Objective: This study aims to investigate changes in lingula mandibulae localization before and after puberty and sex differences. Design: 288 panoramic radiographs evaluated retrospectively were divided into four groups according to pubertal development: under and over 10 years old for females and under and over 11 years old for males. Four anatomic sites were used as reference points: (a) the anterior border of the ramus; (b) the posterior border of the ramus; (c) the deepest point of mandibular notch; and (d) the angulus mandibulae. The ratio of the distances from the lingula mandibulae to points (a) and (b) and the ratio of the distances from the lingula mandibulae to points (c) and (d) were determined. Two-way ANOVA was performed to assess differences between subgroups based on sex and puberty, and a Bonferroni post-hoc test was performed for multiple comparisons. Results: Puberty and sex has a significant interaction effect on the vertical location of the lingula mandibulae. Postpubertal lingula mandibulae is positioned proportionally more anteriorly by prepubertal localization. In addition, the lingula mandibulae is situated more posteriorly in females compared to males. A significant interaction effect of puberty and sex was observed in relation to the vertical positioning of the lingula mandibulae. Conclusions: The spatial localization of the lingula mandibulae and its spatial displacement with age can be used both in estimating sex and the onset of puberty. Changes in the localization of lingula mandibulae according to pubertal development and sex can be used in forensic and anthropological contexts.
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    Evaluation of the Effectiveness of Polyether Silicone-based and Polyvinyl Siloxane Dental Impression Materials for Shielding Scattered Radiation During Radiotherapy
    (Aydın Adnan Menderes University, 2023) Deniz, Yeşim; Aktaş, Çağatay; Işıktaş Acar, Ezgi
    Objective: Radiation-induced oral mucositis is a major problem associated with radiotherapy. This study aimed to investigate the effectiveness of polyether silicone-based (PE) and polyvinyl siloxane (PVS) impression materials in protecting adjacent tissues from radiation scattered from dental materials. Materials and Methods: Amalgam, zirconium, and titanium dental material specimens were covered with 5 mm PE and PVS in the study group. The dental materials were placed in a linear accelerator device at a distance of 100 cm from the radiation source and coincided with a field size of 15x15 mm. Samples placed perpendicular to the central beam were irradiated with 6 MV photons at a fractional daily therapeutic radiation dose of 2 Gy. Thermoluminescent dosimeters (TLD-100) placed 90 degrees lateral to the specimens were used to record the scattered dose data. In the control group, uncovered dental materials were irradiated, and scattered doses were measured by TLD. The TLD data of the study and control groups were compared by independent t-test to analyze the shielding effect of PE and PVS. In addition, the photon stopper properties of PE and PVS were compared. The photon interaction parameters and effective atomic numbers of dental materials were calculated. Results: It was calculated that the PE and PVS significantly prevent the dose enhancement caused by dental materials (p<0.05). There was no difference between impression materials in the photon-stopping properties (p>0.05). Conclusion: PE and PVS can be used as scatter dose shields for the 2 Gy daily fractional dose. This study demonstrates the radiation-shielding properties of PE for the first time.
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    Investigation of Dosage Distributions of Polyvinyl Siloxane Dental Impression Shields for Head and Neck Radiotherapy with Thermoluminances Dosimeters
    (Marmara University, 2023) Ulusoy Öztürk, Habibe; Deniz, Yeşim; Aktaş, Çağatay; Gül Aygün, Esma Başak
    Objective: This study aimed to assess the effects of denture materials on dose distribution on a head and neck radiotherapy-appropriate model and calculate the thickness of a stent by polyvinyl siloxane dental impression material for shielding scattered radiation from dental restorations. Methods: In the first step of the study, 5mm diameter and 5mm height of cylindrical dental material of titanium, zirconia lithium disilicate were irradiated with 6-Megavoltage photons from a clinical linear accelerator. In the second step, dental materials at the center of polyvinyl siloxane thicknesses of 5, 10, and 20mm were irradiated with 2 Gray and 10 Gray fractional doses. Measurements were made using three thermoluminescent dosimeters positioned laterally. The percentage backscattered dose and percentage dose decrease values were calculated to interpret the results. Results: According to the result, dosages scattered from dental materials increased for samples irradiated with 2Gy; a decreased dose was reported for samples irradiated with a 10Gy. 5mm PVS samples provided higher dose attenuation than others. Regardless of dental material, it is seen that the attenuation intensities calculated from TLD-100 dosimeters ranged from 22.7 to 38,62 for 2Gy, and 10.01 to 38,87 for 10Gy. Conclusion: Dental material alters the scattered radiation. In irradiated head and neck cancer patients, a 5mm thick guard is sufficient to prevent radiation diffused from dental materials in clinical usage.
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    Is there a relationship between transverse maxillary deficiency and sella turcica: A cephalometric analysis study?
    (Scientific Scholar, 2021) Deniz, Yeşim; Arslan, Semiha
    Objectives: The aim of this study was to investigate the dimensions and morphological variations of sella turcica and to test whether a relationship exists between sella turcica and transverse maxillary deficiency. Materials and Methods: The cephalometric radiographs of patients older than 17.99 years, which have been taken before the orthodontic treatment, and patient records were analyzed to investigate sella turcica dimensional and morphological analysis. Linear measurements of sella are as follows sella length, sella width, sellar area, sella height anterior, posterior, and median. The sella turcica morphological shape analysis was performed into six groups (normal sella turcica, oblique anterior wall, sella turcica bridge, double contour of floor, irregularities of the posterior part of the dorsum sella, and pyramidal shape of the dorsum sella). The width of the maxillary arch is measured by the digital caliper. Male participants with a maxillary width of less than 30.8 mm and a maxillary width of less than 31.1 mm in female patients in the first molar region were determined as a transverse maxillary deficiency. The mean dimensions of sella turcica and the relationship between cases with transverse maxillary deficiency and non-skeletal anomaly were compared using independent samples t-tests. The transverse maxillary deficiency and the sellar morphology relationship were compared using Chi-square test. Post hoc multiple comparisons and analyzes were performed at 95% confidence interval by Bonferroni correction. Results: The sella length measurements yielded higher values among the patients with transverse maxillary deficiency (P < 0.05). The normal sella morphology had quantitative superiority in patients without skeletal anomaly in comparison with transverse maxillary deficiency cases (P < 0.05). It was observed that the sella turcica bridge had a statistically superiority in patients with transverse maxillary deficiency (P < 0.05). Conclusion: The increased sellar measurement and sella turcica bridging, may provide knowledge about possible transverse maxillary deficiency.
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    Sella tursika köprülenmesi ile maksiller darlık arasındaki ilişkininaraştırılması
    (2020) Deniz, Yeşim; Arslan, Semiha
    Amaç: Bu çalışmanın amacı sella tursika köprülenmesi ile maksiller darlık arasındaki ilişkinin değerlendirilmesidir. Gereç ve Yöntem: Bu retrospektif çalışmada, 2017-2019 yılları arasında ortodonti kliniğinde tedavi görmekte olan 18-30 yaşları arasındaki 73 adet maksiller darlık teşhisi almış olan hasta ile 73 adet herhangi bir iskeletsel anomalisi bulunmayan hastanın sella tursika köprülenme tipleri sefalometrik radyografiler üzerinde karşılaştırıldı. Çalışmaya dahil edilen sefalometrik radyografilerin tümü sistemik açıdan sağlıklı, ortognatik cerrahi veya baş boyun bölgesinden herhangi bir travma geçirmemiş olan ortodonti hastalarına ait iyi kaliteli görüntülerdi. Sella tursika köprülenme tipleri Sınıf I (kalsifikasyon yok), Sınıf II (parsiyel kalsifikasyon) ve Sınıf III (tam kalsifikasyon) olarak sınıflandırıldı. Sella tursika köprülenme tipleri ile çalışma grubu ve kontrol grubu arasındaki ilişki ki- kare testi kullanılarak değerlendirildi. Post Hoc çoklu karşılaştırmalarda Bonferroni düzeltmesi yapılarak %95 güven aralığında analizler sürdürüldü. İstatistiksel anlamlılık düzeyi 0,05 olarak kabul edildi.Bulgular: Sınıf I (kalsifikasyon yok), sella tursika köprülenmesi kontrol grubunda çalışma grubuna göre istatiksel olarak anlamlı düzeyde fazla, Sınıf II (parsiyel kalsifikasyon) sella tursika köprülenmesinin ise çalışma grubunda kontrol grubuna göre daha fazla olduğu görüldü (p<0.05). Cinsiyetle sella tursika köprülenme tipleri arasındaki ilişki karşılaştırıldığında maksiller darlık teşhisi olan kadın hastalarda Sınıf II (parsiyel kalsifikasyon) sella tursika köprülenmesi anlamlı düzeyde fazla görüldü (p>0,05).Sonuç: Bu çalışmanın sonucunda, sella tursika köprülenmesi ile maksiller darlık arasında ilişki gözlemlenmiştir. Sella tursika köprülenmesinin olası maksiller darlık oluşumu hakkında öngörü sağlayabileceği veya hastanın yüz profili hakkında bilgi verebileceği düşünülmektedir. Bu çalışma maksiller darlık ile sella tursika köprülenmesi arasındaki ilişkinin incelendiği ilk çalışma niteliğindedir.
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    Students' Perceptions About the Instructors' Competence in Technology-supported Courses at Dental Faculty: A Cross-sectional Study
    (Aydın Adnan Menderes University, 2023) Çetin Genç, Çiğdem; Deniz, Yeşim; Genç, Celal; Değirmenci, Alpin; Tosun, İlgi
    Objective: The pandemic has highlighted the importance of technology-supported courses throughout the world. Evaluating the perceptions of students attending these courses is important to provide high-quality education. Materials and Methods: This study was carried out on 1st, 2nd, and 3rd-grade dentistry students. The Student Perceptions Scale Regarding the Knowledge of Instructors in Technology - Supported Classrooms was applied to 207 dentistry students. This scale consists of four sub-dimensions: subject matter knowledge (SMK), technological knowledge (TK), knowledge of students' understanding (KSU), and technological pedagogical content knowledge (TPCK). Results: SMK, KSU, and TPCK sub-dimension scores did not significantly differ by gender (p>0.05). However, the mean TK score of females (3.55 +/- 0.47) was found to be significantly higher than that of males (3.28 +/- 0.59) (p=0.001). There was no statistically significant difference among the SMK, TK, KSU, and TPCK sub-dimension mean scores by age (p>0.05). There was a statistically significant difference in the mean scores of the SMK and KSU sub-dimensions by grade (p-values are p<0.001 and p=0.015 respectively). The mean TK and TPCK sub-dimension scores yielded no significant difference by grade (p-values are p=0.368 and p=0.050 respectively). Conclusion: Measuring the quality of technology-assisted teaching and the instructor's TPCK from the student's perspective and determining student perceptions will provide accurate data on the long-term quality of education.
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    The Role of Instagram on Dental Education
    (2021) Geduk, Gediz; Deniz, Yeşim
    Objective: Technological developments affect educational processes, learning methods, and learning environments. Dentistry education should be adapted parallel with technologicaldevelopments for students whose learning habits change with the increasing using of social media and mobile phones. This study aimsto compare the efficacy of the mobile-based education method (Instagram application) and the traditional classroom education method.Material and Methods: The study was conducted with 42 volunteerstudents who had not taken general and oral pathology courses yet.Students (n:21) in the control group took radiological features of theodontogenic and non-odontogenic cysts and odontogenic tumorscourse by the classroom learning method. The study group (n:21) followed the same lessons’ images on the newly opened @beuradyolojiInstagram account. Both groups were trained for 1 hour a week for 4weeks. The knowledge test was held 15 days after the end of thecourses to all students. Paired sample t-test was performed to investigate differences between the mean knowledge test scores of thegroups. Results: The examination average for the study group was71.97±9.3 and the control group was 68.33±8.39. Paired sample t-testshowed no significant difference between the study and controlgroups in knowledge scores (p>0.05). Conclusion: The current studyis the first that investigates the effect of the mobile-based educationmethod on radiological features of the specific cysts and tumors. Thestudy carried out on a limited number of students, shows that the valueof mobile-based education has almost the same effectiveness to classroom education.
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    The usefulness of ultrasonography as a dynamic measurement system for visualizing root canal working length: an in vivo study
    (BMC, 2024) Eren, İrem; Deniz, Yeşim
    ObjectiveAlthough apex locators are generally effective tools for determining root canal working length, they may produce inaccurate results in some cases. The present study aimed to evaluate the efficacy of ultrasonography as an alternative method for measuring root canal length.Materials and methodsForty-seven anterior teeth with apical lesions were selected for the study. Initially, an electronic apex locator was used to measure the working length. Subsequently, ultrasonography was employed to visualize the root apex and determine the working length. During ultrasound imaging, a K-file No. 15 was inserted into the root canal until its tip was visible on the ultrasound monitor. Measurements obtained from both methods were compared using an independent sample t-test. Correlations were assessed with the Pearson correlation coefficient, and agreement was determined using the Bland-Altman plot.ResultsThe mean working canal length was 19.9 mm for the apex locator and 20.6 mm for the ultrasonography-guided method. No significant differences were observed between the data obtained using the apex locator method and the data obtained using the ultrasonography guidance method. Furthermore, a high level of agreement was identified between the two techniques.ConclusionUltrasonography can be used to visualize the apex effectively and determine canal length, especially when canal length determination is uncertain for various reasons.
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    Ultrasound examination of various dental materials and foreign bodies
    (2023) Deniz, Yeşim; Ak, Rüya Sessiz; Eren, Hakan
    Purpose To provide information on the sonographic properties of different foreign bodies and dental materials to help with diagnosis. Materials & Methods The investigation contained 10 various dental materials and foreign bodies that were consisting of composite, glass ionomer cement, gutta percha, suture, wooden, stone, canal file, acrylic, alginate, and silicone impression material. The objects were embedded to chicken meat and imaged using ultrasonography (USG). Their visibility and posterior acoustic behaviors were evaluated by both hockey and linear transducers. The actual sizes of this objects and measured dimensions by transducers were compared. Results Only gutta percha could not be distinguished in chicken meat. No difference was observed between the measurements made with the hockey and linear transducers and the actual size. Conclusion USG is a useful method for detecting and measuring foreign bodies and dental materials in soft tissues.
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    Unveiling Bone and Dental Regeneration Potential of Quince Seed Mucilage-Nanohydroxyapatite Scaffolds in Rabbit Mandibles
    (Wiley, 2025) Çetin Genç, Çiğdem; Yılmaz-Dağdeviren, Hilal Deniz; Deniz, Yeşim; Derkuş, Burak; Değirmenci, Alpin; Arslan, Yavuz Emre
    Donor-side morbidity of autografting for maxillofacial region defect regeneration has directed attention to bioengineered scaffolds. Composite scaffolds that mimic the bone extracellular matrix (ECM) are the potential candidates for defect reconstruction. Herein, a plant-based regenerative hydrogel, quince seed mucilage (QSM), was enriched with the nanohydroxyapatite (nHAp) particles to construct composite scaffolds (QSM/nHAp). The emerging scaffold is able to induce cellular spheroid formation and regenerate the critical-sized bilateral mandibular defects in rabbits. The macroscopic observations, histochemical (HC) and immunohistochemical (IHC) stainings, mu-computer tomography (CT) scanning, quantitative real time-polymerase chain reaction (qRT-PCR) analyses, and scanning electron microscopy (SEM) imaging revealed that all QSM/nHAp scaffolds were swelled with host blood, filled the whole cavity, and sustained cellular infiltration without adverse reactions. The gradual biodegradation profile of the scaffolds improved bone regeneration by releasing nHAp particles from the scaffold. Strikingly, co-development of dental and bone regeneration was observed for all QSM/nHAp groups beginning after day 21. Moreover, QSM/nHAp scaffolds induced expression (> 2-fold) of bone and dental-related gene and protein expressions at the grafted area and sustained a proper platform for maxillofacial remodeling. Therefore, we strongly believe that such biocompatible plant-based constructs, compared with conventional medical devices used in maxillofacial surgery, could support and induce simultaneous bone and dental regeneration due to the intrinsic dynamics of the material.

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