Yazar "Cirali, Digdem Erdener" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • [ X ]
    Öğe
    A new phosphazene derivative, spiro-N3P3[(O2C12H8)2(OC6H6N-3)2], and its Ru(II) complex: Syntheses, crystal structure, catalytic activity and antimicrobial activity studies
    (Pergamon-Elsevier Science Ltd, 2015) Cirali, Digdem Erdener; Dayan, Osman; Ozdemir, Namik; Hacloglu, Nurcihan
    A cyclotriphosphazene ligand containing the spirocyclic 2,2'-dioxybiphenyl group and 2-methy1-3-pyridyloxy moieties was synthesized. A Ru(11) complex was prepared from the reaction of [RuCl2(p-cymene)](2) with this ligand. The structures of the ligand and the Ru(II) complex were characterized by FT-IR, H-1 and P-31 NMR spectroscopy. In addition, the molecular structure of the ligand was confirmed by X-ray crystallography. The Ru(II) complex was used as catalyst for the Catalytic Transfer Hydrogenation (CTH) of p-substituent acetophenone derivatives in the presence of KOH. The antimicrobial activities of the ligand and the complex have also been studied. The antimicrobial activities have been screened in vitro against Gram-positive (Staphylococcus aureus ATCC 6538, Bacillus cereus ATCC 7064, Listeria monocytogenes ATCC 15313, Micrococcus luteus La 2971) and Gram-negative (Escherichia coil ATCC 11230, Klebsiella pneumoniae UC57, Pseudomonas aeruginosa ATCC 27853, Proteus vulgaris ATCC 8427, Enterobacter aerogenes ATCC 13048) bacteria and yeast cultures (Candida albi cans ATCC 10231, Kluyveromyces fragills NRRL 2415, Rhodotorula rubra DSM 70403) using both the disk diffusion and dilution methods. (C) 2015 Elsevier Ltd. All rights reserved.
  • [ X ]
    Öğe
    SYNTHESIS OF TETRANUCLEAR RUTHENIUM (II) COMPLEX OF PYRIDYLOXY-SUBSTITUTED 2,2?-DIOXYBIPHENYL-CYCLOTRIPHOSPHAZENE PLATFORM AND ITS CATALYTIC APPLICATION IN THE TRANSFER HYDROGENATION OF KETONES
    (Taylor & Francis Ltd, 2015) Cirali, Digdem Erdener; Dayan, Osman
    Cyclophosphazene was reacted with biphenyl-2,2'- diol to afford the N3P3Cl4(O2C12H8) (1). Then, pyridyloxy cyclophosphazene, spiro N3P3(O2C12H8)(O-C5H4N-3)(4) (2) was synthesized from the reaction of 3-hydroxy pyridine and compound 1. The reaction of 2 with [RuCl2(p-cymene)](2) afforded Ru(II) complex (3). The structures of the ligand and complex are characterized by elemental analysis, FT-IR, H-1-, and P-31-NMR spectroscopy. Ru(II) complex has been employed as catalysts for the transfer hydrogenation of acetophenone in the presence of KOH using 2-propanol as a hydrogen source. The complex has demonstrated good catalytic activity in transfer hydrogenation of ketones.
  • [ X ]
    Öğe
    Synthesis, characterization and catalytic, cytotoxic and antimicrobial activities of two novel cyclotriphosphazene-based multisite ligands and their Ru(II) complexes
    (Wiley, 2015) Cirali, Digdem Erdener; Uyar, Zafer; Koyuncu, Ismail; Hacioglu, Nurcihan
    Two novel cyclotriphosphazene ligands (2 and 3) bearing 3-oxypyridine groups and their corresponding Ru(II) complexes (4 and 5) were synthesized and their structures were characterized using Fourier transform infrared, H-1 NMR and P-31 NMR spectroscopic data and elemental analysis. The Ru(II) complexes were used as catalysts for catalytic transfer hydrogenation of p-substituted acetophenone derivatives in the presence of KOH. Additionally, the cytotoxic activities of compounds 2, 3, 4, 5 were evaluated against PC3 (human prostate cancer), DLD-1 (human colorectal cancer), HeLa (human cervical cancer) and PNT1A (normal human prostate) cell lines. Finally the antimicrobial activities of compounds 2, 3, 4, 5 were evaluated against a panel of Gram-positive and Gram-negative bacteria and yeast cultures. The complexes showed efficient catalytic activity towards transfer hydrogenation of acetophenone derivatives, especially those bearing electron-withdrawing substituents on the para-position of the aryl ring. The compounds were found to have moderate to high cytotoxic and antimicrobial activities, and Ru(II) complexation enhanced both cytotoxic and antimicrobial activities in comparison with the parent compounds. Copyright (c) 2015 John Wiley & Sons, Ltd.