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Öğe Association between teething and independent walking in healthy children(2015) Kaymaz, Nazan; Yıldırım, Şule; Cevizci, Sibel; Çimen, Mehmet; Topaloğlu, Naci; Binnetoğlu, Fatih Köksal; Tekin, MustafaKaymaz N, Yıldırım Ş, Cevizci S, Çimen M, Topaloğlu N, Binnetoğlu FK, Tekin M, Özmert EN. Association between teething and independent walking in healthy children. Turk J Pediatr 2015; 57: 53-59.Developing teeth provide a reliable indication of maturation and biological age. The objective of this study was to establish whether there is any association between the time of emergence of the first primary tooth and the time when independent walking occurs. A cross-sectional study was conducted with a sample of 206 healthy children (95 girls and 111 boys) aged 12 to 60 (mean: 29.79±0.66) months who were able to walk independently. The study was conducted using a questionnaire that was filled out by the parents. The first primary tooth emerged at 6.86±0.14 (min: 3–max: 13) months; the mean independent walking time was 12.58±2.15 (min: 8.50–max: 24.00) months. There was no correlation between the first teething and independent walking times (r=0.045, p=0.523). Factors such as breastfeeding status, intake of vitamins, walker usage and body mass index were found not to affect the time of either emergence of the first deciduous tooth or independent walking. To the best of our knowledge, this is the first paper in literature to have researched the relationship between the time of emergence of the first deciduous tooth and that of independent walking. It should be explained to parents that there is no relationship between the two in order to resolve anxiety when their child acquires a tooth but does not walk, or vice versaÖğe Delayed time of atrial conduction in children with Familial Mediterranean Fever(2021) Şehitoğlu, M.Hilal; Binnetoğlu, Fatih Köksal; Aylanç, Hakan; Yıldırım, Şule; Kaymaz, Nazan; Özdemir, ÖztürkIntroduction: Familial Mediterranean Fever (FMF) is a disease with recurrent fever, characterized by painful, noninfectious inflammation of the serous membranes. It mostly affects Armenians, Turks, Arabs and Jews. Prolonged inflammation in FMF may lead to atrial fibrosis which can cause the deterioration of atrial conduction time and refractory periods of atrial myocardium. In the present study we aimed to assess atrial conduction time in children with FMF. Methods: The study included 36, children diagnosed with FMF(17 males/19 females, 13 (7-15) years) and 20 control(7 males/13 females, 11 (9- 16) years) cases in our Pediatric Outpatient Clinic between October 2015 and October 2016. Tissue Doppler Echocardiography (TDE) measurements of intra-and interatrial electromechanical delay were done. P wave dispersion (Pdisp) was calculated from the 12-lead electrocardiogram. Results: Inter-atrial (Lateral PA– Tricuspid PA) and Intra-left (Lateral PA-Septal PA) atrial electromechanical delay were significantly longer in FMF patients (P<0.001,respectively). (PA: the time range between the beginning of the P wave in the surface electrocardiogram and the beginning of the tissue Doppler late diastolic wave A). Also, P-wave dispersion (Pdisp) were significantly higher in FMF patients ( p= 0.002). Conclusions: This study shows that atrial electromechanical delay and Pdisp are prolonged in children with FMF. We recommend that atrial conduction time be measured for children diagnosed with FMF.Öğe Early detection of myocardial deformation by 2D speckle tracking echocardiography in normotensive obese children and adolescents(2015) Binnetoğlu, Fatih Köksal; Yıldırım, Şule; Topaloğlu, Naci; Tekin, Mustafa; Kaymaz, Nazan; Aylanç, Hakan; Karakurt, HasanObjective: To evaluate the left venticular myocardial deformation parameters in normotensive obese children and adolescents by using 2-D speckle tracking echocardiography. Methods: This observational cross-sectional study included 69 children and adolescents (aged between 10-18), 38 were normotensive obese and 31 were normal weighted. All children underwent detailed two- dimentional, Doppler and two-dimentional speckle tracking echocardiography. Student t-test, Mann-Whitney U test, chi-square test and Pearson s correlation were used in statistical analysis. Multiple linear regression analysis was used the determine independent variables on global longitudinal strain (GLS). Results: While in normal limits, diastolic blood pressure was significantly higher in obese group. Left ventricular end-diastolic diameter (LVDd) and end-systolic diameter (LVDs), interventricular septal thickness (IVSd), left ventricular posterior wall thickness (LPWD) and left ventricular mass index (LVM)/height2.7 were significantly higher in obese group compared to healthy peers (p=0.004, p=0.011, p<0.001, p=0.001, p<0.001) respectively. Obese subjects had reduced global longitudinal strain (GLS) values (p=0.001). Multiple linear regression analysis using the stepwise method were performed to assess the independent variables (age, body mass index, insulin resistance, systolic blood pressure, diastolic blood pressure, left ventricular diameters and LVM index (g/m2.7) affecting the dependent variable GLS. GLS was found significantly correlated with body mass index (BMI) (β:0.440, p:0.001; 95% CI: 0.104-0.311). Conclusion: Left ventricular strain parameters obtained by two dimentional speckle tracking echocardiography were diminished in obese children compared to normal subjects indicating that obesity in childhood is linked to decreased myocardial deformation even in the absence of comorbidities in early stages. (Anatolian J Cardiol 2015; 15: 151-7)Öğe Effect of infant feeding on epicardial fat thickness in normal weighted children(Anatolian Journal of Clinical Investigation, 2015) Yildirim, Şule; Binnetoğlu, Fatih Köksal; Aylanç, Hakan; Battal, Fatih; Tekin, Mustafa; Kaymaz, Nazan; Topaloğlu, NaciEFT is an independent predictor of coronary artery disease and closely associated with increased risk of metabolic syndrome and cardiovascular complications. This study aimed to evaluate the effect of breastfeeding on EFT thickness in normal-weighted children to predict the increased risk of coronary artery disease. This study included 84 normal weighted children (aged between 5-10 years), who admitted to pediatric cardiology department from October 2013 to March 2014. The patients were divided into 3 groups according to the feeding regimen in the first 6 months of year. Group 1 consisted of children who were exclusively breastfed in the first 6 months (n: 45). Group 2 consisted of children who were fed with both breast milk and formula (n: 37) and the Group 3 included children who only fed with formula (n: 2). Transthoracic echocardiography was performed and epicardial fat tissue measured. EFT was statistically lower in Group 1 compared to Group 2. EFT was highest in Group 3. The children who breastfed for longer time had low EFT thickness and this correlation was statistically significant (r= -0,457, p<0,001). In conclusion echocardiographically measured EFT thickness is low in breastfed children compared to formula-fed children. © 2015, Anatolian Journal of Clinical Investigation. All rights reserved.Öğe Left ventrİcular noncompaction and ventricular tachycardia diagnosed at preparticipatİon screening(Anatolian Journal of Clinical Investigation, 2015) Binnetoğlu, Fatih Köksal; Yildirim, Şule; Karadeniz, Cem; Topaloğlu, Naci; Tuzcu, Volkan; Kaymaz, NazanLeft ventricular noncompaction is a rare genetic cardiomyopathy which is characterized by excessive trabeculated and spongioform left ventricule. Heart failure, thromboembolism including stroke, ventricular arrhythmia and Wolf Parkinson White Syndrome are the main complications. In this study we present a patient with arrhythmia diagnosed during preparticipation screening and succesfully treated with radiofrequency ablation and flecainide. © 2015, Anatolian Journal of Clinical Investigation. All rights reserved.Öğe Prolonged pacifier usage in infancy does not cause eating behavior problem later(2015) Kaymaz, Nazan; Yıldırım, Şule; Cevizci, Sibel; Bulur, Nurcan; Topaloğlu, Naci; Binnetoğlu, Fatih Köksal; Tekin, MustafaKaymaz N, Yıldırım Ş, Cevizci S, Bulur N, Topaloğlu N, Binnetoğlu FK, Tekin M, Kılıç M, Özmert EN. Prolonged pacifier usage in infancy does not cause eating behavior problem later. Turk J Pediatr 2015; 57: 487-491.The objective of this study conducted in children aged 3-7 years was to determine whether pacifier use during infancy is associated with eating problems in later periods. A total of 85 children (55.2 ±12.3 months) admitted to hospital with eating problems and with no organic pathology in scans, and 97 healthy children (52.24±10.97 months) without eating problems, were assigned to case and control groups, respectively. Eating problems were classified into five groups and investigated via a questionnaire. The presence of eating problems was analyzed for association with pacifier use. There was no significant difference between the two groups in terms of pacifier use (chi-square test: 0.141, p=0.707), and pacifier use is not related to a poor appetite in later periods. Pediatric healthcare providers and parents should be informed with regard to the subject.Öğe Right Aortic Arch with Aberran Left Subclavian Artery; Accompanied with Crossed Pulmonary Arteries: A Rare Association(2016) Aylanç, Hakan; Aylanç, Nilüfer; Binnetoğlu, Fatih Köksal; Battal, Fatih; Adam, Gürhan; Tekin, Mustafa; Kaymaz, Nazan[Abstract Not Available]