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    Evalulation of Optical Coherence Tomography Measurements inPeritoneal Dialysis Patients
    (2021) Bek, Sibel; Batman, Adnan; Eren, Necmi; Tuğan, Büşra Yılmaz; Bakırdöğen, Serkan
    INTRODUCTION: Optical coherence tomography (OCT) is anon-invasive ocular imaging technique widely used nowadays.There are limited studies focusing on the OCT findings in PDpatients. Our aim is to compare retinal changes of peritonealdialysis (PD) patients with healthy control group by using OCT and investigate the effects of age, gender and duration of PDon these parameters. METHODS: In this cross-sectional study right and left eyes of32 patients and twenty right and left eyes of ten healthycontrols were included. Detailed ophthalmologicalexaminations with central macular thickness (CMT),peripapillary retinal nerve fiber layer (RNFL) thickness, andchoroidal thickness (using EDI-OCT) were measured. Macularthickness was measured at five different areas:central,superior, temporal, inferior and nasal. Theperipapillary RNFL thickness was analysed in six differentareas: temporal, inferotemporal, inferonasal, nasal,superonasal and superotemporal. RESULTS: Sixty-four eyes of 32 patients (18 males, 14females; aged 20 to 60 years, mean 48.67±12.25 years) with amean duration of PD of 46.80 months were included. Therewas a significant difference of macular thickness in the central,temporal, nasal, inferior and superior quadrants betweencontrols and PD patients (p < 0.05). Vitamin D3supplementation was linked to decreased macular thickness incentral, temporal, superior, nasal and inferior quadrants(p<0.05). There was a positive correlation between macularthickness in central and temporal quadrants with residualrenal function (p=0.006, p=0.019). DISCUSSION AND CONCLUSION: OCT revealed asignificant reduction of macular thickness in all quadrants inPD patients.
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    The Association Between Delayed Graft Function and Renal Resistive Index in Kidney Transplant Recipients
    (Cureus, Inc., 2021) Bakırdöğen, Serkan; Kurt, Hasan Anıl; Kamış, Fatih; Bek, Sibel; Erbayraktar, Ayşegül
    Background and objectives Delayed graft function (DGF) may increase the risk for kidney graft dysfunction. Renal resistive index (RRI) in Doppler ultrasonography is useful in measuring blood flow changes in kidneys which is indicative of tubulointerstitial damage. Most of the diseases in DGF etiology are related to tubulointerstitium and arteries of the kidneys. In this study, we investigated whether there is a relationship between delayed graft function and renal resistive index in kidney transplant recipients (KTR). Materials and methods Patients who underwent kidney transplantation were included in this retrospective study. KTR were divided into two groups as DGF (+) and DGF (-). Comparison of RRI values of DGF (+) and DGF (-) groups according to the measurements at different times. Results The findings showed that both RRI measurements (post-transplant in the first week and the end of the first year) of the DGF (+) group were higher than DGF (-) group (p=0.001 and p=0.003, respectively). The interaction of measurements and DGF did not have an effect on RRI (p>0.05). Conclusion The value of RRI in the DGF (-) group was lower than DGF (+) group in the first week after kidney transplantation.