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    Prognostic Value of the Neutrophil-Lymphocyte Ratio in Patients With ST-Elevated Acute Myocardial Infarction
    (Sage Publications Inc, 2015) Gazi, Emine; Bayram, Basak; Gazi, Sabri; Temiz, Ahmet; Kirilmaz, Bahadir; Altun, Burak; Barutcu, Ahmet
    The predictive value of leukocyte counts has been reported in patients with acute myocardial infarction (AMI). We aimed to evaluate the predictive value of the total leukocyte count and neutrophil-lymphocyte (N/L) ratio for mortality due to AMI. A total of 522 patients with acute ST-elevated MI were included in the study. The study population was divided into tertiles based on admission N/L ratio values. High (n = 174) and low N/L (n = 348) ratio groups were defined as patients having values in the third tertile (> 5.77) and lower 2 tertiles (<= 5.77), respectively. The high N/L ratio group had a significantly higher incidence of in-hospital cardiovascular mortality (13.8% vs 4.6%, P <.001). An N/L ratio > 5.77 was found to be an independent predictor of in-hospital cardiovascular mortality (hazard ratio: 3.78, 95% confidence interval: 1.71-8.30, P =.001). A high N/L ratio is a strong and independent predictor of in-hospital cardiovascular mortality of AMI with ST elevation.
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    Propafenone-induced cardiac arrest: full recovery with insulin, is it possible?
    (W B Saunders Co-Elsevier Inc, 2013) Bayram, Basak; Dedeoglu, Erhan; Hocaoglu, Nil; Gazi, Emine
    Propafenone may cause mental depression, mania, convulsion, metabolic acidosis, hypotension, prolonged QRS, atrioventricular block, and cardiac arrest if it is taken at a dose greater than recommended. There is no standard specific treatment or antidote for a propafenone overdose, and life-supporting treatments are applied in these cases. In this case report, we report a case of a 15-year-old female patient who experienced cardiac arrest after an oral propafenone overdose. She was successfully treated using cardiopulmonary resuscitation, which took approximately 1.5 hours. Dopamine infusion, sodium bicarbonate, and insulin treatment were also administered to the patient. High-dose insulin treatment may be an effective treatment of propafenone poisoning.