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Öğe An unusual case of ectopic variceal bleeding treated with percutaneous intervention(Univ Catholique Louvain-Ucl, 2014) Adam, Gurhan; Gunes, Fahri; Akbal, Erdem; Cinar, Celal; Bozkaya, Halil; Resorlu, Mustafa; Aylanc, Nilufer[Anstract Not Available]Öğe Evaluation of paravertebral muscle atrophy and fatty degeneration in ankylosing spondylitis(Taylor & Francis Ltd, 2017) Resorlu, Hatice; Savas, Yilmaz; Aylanc, Nilufer; Gokmen, FerhatAim: The purpose of this study was to assess morphological changes in the paravertebral muscles in patients with ankylosing spondylitis. Materials and methods: Fifty-one patients diagnosed with ankylosing spondylitis and a 50 member control group were included in the study. The surface area of the multifidus and erector spinae muscles was measured at four levels between L1 and L5, and fatty degeneration in these muscles was scored. Lumbosacral and lumbar lordotic angles were determined for the patient and control groups. Results: Loss of muscle cross-sectional area compatible with atrophy was present at all four levels in the paraspinal muscles in patients with ankylosing spondylitis. A negative correlation was observed between paravertebral muscle area and duration of disease at three levels, but not at L1-2. Although muscle area decreased with the duration of disease at the L1-2 level, this was not statistically significant (r=-0.195, p=0.171). Comparison of intramuscular fatty degeneration between the groups revealed increased intramuscular fat at all levels in patients with ankylosing spondylitis, with the exception of L3-4, and a positive correlation between fatty degeneration and duration of disease was determined at all levels. Conclusion: Chronic inflammation, cytokine-mediated fibrosis, immobilization, and postural changes in ankylosing spondylitis contribute to fatty degeneration and atrophy in the paravertebral muscles.Öğe Gaucher's disease in a patient presenting with hip and abdominal pain(Assoc Medica Brasileira, 2017) Resorlu, Mustafa; Aylanc, Nilufer; Karatag, Ozan; Toprak, Canan AkgunGaucher's disease is characterized by glucocerebroside accumulation in the cells of the reticuloendothelial system. There are three subtypes. The most common is type 1, known as the non-neuropathic form. Pancytopenia, hepatosplenomegaly and bone lesions occur as a result of glucocerebroside accumulation in the liver, lung, spleen and bone marrow in these patients. Findings associated with liver, spleen or bone involvement may be seen at radiological analysis. Improvement in extraskeletal system findings is seen with enzyme replacement therapy. Support therapy is added in patients developing infection, anemia or pain. We describe a case of hepatosplenomegaly, splenic infarction, splenic nodules and femur fracture determined at radiological imaging in a patient under monitoring due to Gaucher's disease.Öğe Giant Fibrolipoma Extending Throughout a Whole Extremity: A Rare Child Case Report(Derman Medical Publ, 2016) Aylanc, Nilufer; Golge, Umut Hatay; Aylanc, Hakan; Resorlu, Hatice; Goksel, FerdiWe present the case of a 4-year-old boy with congenitally asymmetrical lower extremities, his left being bigger than his right. The patient underwent imaging modalities after birth; a huge lipomatoid proliferation on his left thigh extended throughout the limb from the hip to the distal foot, showing isointensity with lipoid tissue. After surgical resection of his left foot, fibrolipoma was diagnosed. A giant fibrolipoma of the whole extremity occurring in a pediatric patient is a rarity.Öğe Instrascrotal Non-Testicular Ancient Schwannoma: A Rare Case Report(Derman Medical Publ, 2013) Uysal, Fatma; Gulpinar, Murat Tolga; Adam, Gurhan; Resorlu, Mustafa; Aylanc, NiluferSchwannomas, which may occur in any region of the body, is very rare in the scrotum. Schwannomas are tumors that originate from Schwann cells and, theoretically, could affect any nerve. In spite of the rich innervation of the genital area, these kinds of tumors are not common in the scrotum. A 66 year old man presented with a 1-year history of painless scrotal swelling. Scrotal ultrasonography and magnetic resonance imaging revealed intrascrotal and extratesticular mass in the mid- scrotal region. Surgical excision was undertaken and histology was an ancient schwannoma of the scrotum. We report one case of ancient schwannomas of the scrotum with a review of the literature.Öğe Investigation of Blood Betatrophin Levels in Obese Children with Non-Alcoholic Fatty Liver Disease(Korean Soc Pediatric Gastroenterology & Nutrition, 2018) Battal, Fatih; Turkon, Hakan; Aylanc, Nilufer; Aylanc, Hakan; Yildirim, Sule; Kaymaz, Nazan; Uysal, SemaPurpose: The prevalence of obesity has significantly increased among children and adolescents worldwide and is becoming an important health care problem in parallel with the increased prevalence of obesity pediatric non-alcoholic fatty liver disease. Betatrophin is a newly define hormone that is commonly secreted by liver and plays role in glucose tolerance. This study aimed to investigate the relationship between serum betatrophin levels and non-alcoholic fatty liver disease in obese children. Methods: The study included 40 obese children with a body mass index (BMI) above 95th centile, and 35 non-obese subjects with a BMI 3-85th centile, whose age and gender were similar to those of the patient group. For the evaluation of metabolic parameters fasting serum glucose, insulin, alanine aminotransferase, aspartate aminotransferase, lipid profile and serum betatrophin levels were measured. Total cholesterol: high-density lipoprotein cholesterol and low-density lipoprotein cholesterol: high-density lipoprotein cholesterol ratios were calculated as atherogenic indices. Results: Serum betatrophin levels of the obese subjects were similar to that of non-obese subjects (p=0.90). Betatrophin levels were not correlated with the metabolic parameters. Conclusion: In the present study, levels of betatrophin are not different between obese and insulin resistant children and non-obese subjects, and they are not correlated with atherogenic indices. To elucidate the exact role of betatrophin in obesity, further studies are required to identify the betatrophin receptor and/or other possible cofactors.Öğe Is Epidural Fat Affected by Peripheric or Visceral Adipose Tissue? A Radiologic View(Duzce Univ, 2019) Aylanc, Nilufer; Resorlu, Mustafa; Adam, GurhanObjective: We evaluated adipose tissue distribution in different anatomical localizations by comparing with epidural fat tissue. Methods: Sixty patients' (28 female and 32 male) included in our study had abdominal computerized tomography and lumbar magnetic resonance images evaluated retrospectively. Subcutaneous and intraabdominal fat tissue thickness was compared with perirenal and epidural fat. The relationship with demographic characteristics of patients was investigated. Results: Mean value of subcutaneous fat thicknesses were higher in females (29.9 +/- 24.2 mm in females and 16.2 +/- 24.5 mm in males), while perirenal fat tissue area was higher in males than females (2118.4 +/- 2327.1 mm2 and 1204.1 +/- 851.3 mm2 respectively). There was no significant difference in intraabdominal and perirenal fat tissue measurements according to gender (p=0.407, p=0.390; respectively). Also subcutaneous, intraabdominal and perirenal fat tissue measurements showed increments in association with gender (r=0.33, p=0.010; r=0.37, p=0.004; r=0.51, p=<0,001; respectively); however no relationship was detected with epidural fat area (p=0.519). Subcutaneous and intraabdominal fat thicknesses were not related with epidural fat (p values 0.434 and 0.271, respectively); and there was a statistical relationship between perirenal and epidural fat (p=0.010). Conclusions: Increases in subcutaneous and intraabdominal fat tissue thickness with waist circumference was an expected finding, but no correlation was detected with epidural fat. Thus, we think that the amount of epidural fat does not change with obesity. Also, we concluded that while perirenal fat measurements were higher in the male group and correlated with epidural fat, androgenic effects can play a role in changing the amount of perirenal and epidural fat tissue. This result may be helpful in management of epidural pathologies, though there is a need for supportive studies.Öğe Isolated muscle involvement in hydatid cyst(Bmj Publishing Group, 2024) Ertem, Senay Bengin; Resorlu, Mustafa; Aylanc, Nilufer; Kamis, FatihAlthough hydatid cyst, caused by Echinococcus granulosus, can develop in any part of the body, involvement of the liver and lung represents approximately 90% of all cases. Involvement of the musculoskeletal system is comparatively rare. Diagnosis is difficult because symptoms are non-specific. We present a case, together with the imaging findings, in order to draw attention to the exclusion of hydatid cyst before surgery or biopsy in patients with muscular pain and a palpable mass.Öğe Posterior reversible encephalopathy with brainstem involvement(Springer-Verlag Italia Srl, 2018) Resorlu, Mustafa; Karatag, Ozan; Aylanc, Nilufer; Ozturk, Muhsin Ozgun; Toprak, Canan Akgun[Anstract Not Available]Öğe Prospective evaluation of the renal morphology and vascular resistance in patients with ankylosing spondylitis.(Soc Romana Ultrasonografe Medicina Biologie-Srumb, 2015) Resorlu, Mustafa; Gokmen, Ferhat; Resorlu, Hatice; Adam, Gurhan; Aylanc, Nilufer; Akbal, Ayla; Ozdemir, HuseyinAims: To evaluate renal morphology, prevalence of urinary stone disease, renal perfusion and resistance to renal blood flow in patients with ankylosing spondylitis(AS). Material and methods: Thirty-eight patients diagnosed with AS and with normal basal renal functions, together with 38 healthy individuals matched in terms of age, sex, blood lipid profile and body mass index, were included. Total cholesterol, triglyceride, urea, creatinine and glucose levels were measured in both groups, as well as vitamin D, erythrocyte sedimentation rate (ESR) and C-reactive protein in the AS group. Renal dimensions, parenchymal echogenicity, presence of stone and renal resistive index (RRI) from the interlobular artery level were measured, and correlations with clinical and laboratory parameters were assessed. Results: Thirty-eight patients diagnosed with AS (age 42.4 +/- 11.5, 24 male, 14 women) and a control group of 38 healthy individuals (age 41.7 +/- 10.8, 23 male, 15 female) were included in the study. Renal stone was present in 7 patients (18.4%) in the AS group and 4 subjects (10.5%) in the control group. There was no significant difference in prevalence of stone between the groups (p=0.516). RRI values were significantly higher in the patients with AS (0.63 +/- 0.06) compared with the control group (0.59 +/- 0.03, p=0.001). Significant correlations were determined between RRI and age, triglyceride level, body mass index and length of disease. Conclusions: Renal Doppler is an important examination in early diagnosis and monitoring of renal changes in AS patients since renal complications in AS develop in the chronic and follow a subclinical course.Öğe Relationship between Abdominal Aortic Intima Media Thickness and Central Obesity in Children(Karger, 2016) Aylanc, Hakan; Aylanc, Nilufer; Yildirim, Sule; Tekin, Mustafa; Battal, Fatih; Kaymaz, Nazan; Binnetoglu, Fatih KoksalBackground: Childhood obesity is one of the important risk factors for early atherosclerosis. We aimed to evaluate the effect of obesity on abdominal aortic intima media thickness (aaIMT) in children. Methods: We consecutively recruited 60 obese and 28 healthy children from the outpatient clinic of pediatrics. In all patients, BMI, waist circumference (WC) and hip circumference (HC) were measured, and fasting serum lipid profile, plasma glucose and plasma insulin were studied. Homeostasis model assessment-estimated insulin resistance (HOMA-IR) was calculated for the obese group. All children underwent ultrasonography to evaluate hepatosteatosis and to measure aaIMT. Results: There was a significant difference between the groups in terms of aaIMT, insulin, glucose, HOMA-IR, total cholesterol, low-density lipoprotein, triglyceride and hepatosteatosis. aaIMT was 1.12 +/- 0.25 and 0.61 +/- 0.18 mm in the obese and nonobese groups, respectively (p < 0.001). In the obese group, there was a positive correlation between aaIMT and WC, WC/height ratio, BMI, HC and hepatosteatosis (p < 0.05 for all), with the highest significance for WC. Conclusions: This study showed that aaIMT was significantly higher in obese children than in nonobese children, and that WC was a strong predictor for aaIMT. Early detection of an increased aaIMT in obese children may guide the follow-up of these patients in terms of developing atherosclerosis and its complications. (C) 2015 S. Karger AG, BaselÖğe Role of pleural fluid attenuation values on CT for hemothorax diagnosis in trauma patients(E-Century Publishing Corp, 2018) Kalkan, Esin Akgul; Aylanc, NiluferBackground and aim: Hemothorax is a critical issue in patients with chest trauma. It should be diagnosed quickly and accurately. The study's aim was to define the potential role of pleural fluid (PF) attenuation value determined on computerized tomography (CT) for the diagnosis of traumatic hemothorax. Methods: From 01.07.2011 to 01.07.2016, patients with PF detected on CT with tube thoracostomy were reviewed. On CT sections, PF attenuation values taken from levels where pleural fluid had the most intense appearance were measured as Hounsfield Units (HU). The relationship between HU values and chest traumatic findings, macroscopic discharge diagnosis, peripheral blood Hb and Htc levels and CT protocol were investigated. Results: Thirty eight cases were reviewed in the study group. All PF HU values were determined to be more than 20.0 HU. PF attenuation values were more than 35 HU in 71.1% (n:27) of the cases and between 20.0 and 34.9 for 28.9% (n:11). In the subgroup with hemorrhagic fluid drained from the thoracic cavity, HU values were often higher than 35. For the sub-groups with and without coexisting traumatic findings, there was no statistically significant difference in terms of PF density being below or above 35 HU. No statistically significant correlation was detected between PF HU values and age, peripheral blood Hb and Htc values. Conclusion: For thorax trauma cases, PF attenuation values were between 20.0 to 34.9 HU, and more than 35 HU. Patients with acute trauma who have PF with attenuation value below 35 HU should be considered as hemothorax primarily, even with no coexisting traumatic findings on CT scans.Öğe The accuracy of urinary ultrasound in the diagnosis of urinary stone disease in patients with acute flank pain: is it influenced by the time of ultrasound performance during the day or week?(Springer Wien, 2015) Resorlu, Mustafa; Abdulmajed, Mohamed Ismat; Resorlu, Eylem Burcu; Ates, Can; Uysal, Fatma; Adam, Gurhan; Aylanc, NiluferThe aim of this article is to investigate the possible impact of timing of ultrasound (US) during the day or week on its diagnostic accuracy. We analyzed the records of 500 patients who underwent an initial urinary US, followed by a noncontrast computed tomography (NCCT) for the assessment of urinary stone disease. The sensitivity, specificity, negative and positive predictive values, negative and positive likelihood ratio, and overall diagnostic accuracy rates of US and were analyzed at different times of the day or week. The specificity and diagnostic accuracy of urinary US showed a decline toward the middle of the week followed by a steady rise by the end of the week, higher sensitivity for urinary US was noticed around mid-week. On the other hand, when urinary US results are subgrouped according to the time of the day they are performed, the specificity remained generally stable but the sensitivity and diagnostic accuracy showed lowest levels between 11:00 a.m. and 02:00 p.m. and between 04:00 p.m. and 05:00 p.m. Although some observational differences between sensitivity, specificity, and diagnostic accuracy of urinary US performed at different times of the day or week are seen, these differences were not statistically significant. Our study showed no significant influence of US timing on its diagnostic accuracy. A larger randomized prospective series is necessary to evaluate the impact of different factors on precision and accuracy in US reporting and, hence, the diagnostic accuracy of urinary US in identifying urinary stone disease.Öğe The relation between chondromalacia patella and meniscal tear and the sulcus angle/trochlear depth ratio as a powerful predictor(Ios Press, 2017) Resorlu, Hatice; Zateri, Coskun; Nusran, Gurdal; Goksel, Ferdi; Aylanc, NiluferPURPOSE: To investigate the relation between chondromalacia patella and the sulcus angle/trochlear depth ratio as a marker of trochlear morphology. In addition, we also planned to show the relationship between meniscus damage, subcutaneous adipose tissue thickness as a marker of obesity, patellar tilt angle and chondromalacia patella. METHODS: Patients with trauma, rheumatologic disease, a history of knee surgery and patellar variations such as patella alba and patella baja were excluded. Magnetic resonance images of the knees of 200 patients were evaluated. Trochlear morphology from standardized levels, patellar tilt angle, lateral/medial facet ratio, subcutaneous adipose tissue thickness from 3 locations and meniscus injury were assessed by two specialist radiologists. RESULTS: Retropatellar cartilage was normal in 108 patients (54%) at radiological evaluation, while chondromalacia patella was determined in 92 (46%) cases. Trochlear sulcus angle and prepatellar subcutaneous adipose tissue thickness were significantly high in patients with chondromalacia patella, while trochlear depth and lateral patellar tilt angle were low. The trochlear sulcus angle/trochlear depth ratio was also high in chondromalacia patella and was identified as an independent risk factor at regression analysis. Additionally, medial meniscal tear was observed in 35 patients (38%) in the chondromalacia patella group and in 27 patients (25%) in the normal group, the difference being statistically significant (P - 0.033). CONCLUSIONS: An increased trochlear sulcus angle/trochlear depth ratio is a significant predictor of chondromalacia patella. Medial meniscus injury is more prevalent in patients with chondromalacia patella in association with impairment in knee biomechanics and the degenerative process.Öğe Thorax Computed Tomography Findings in Non-Traumatic Cases Hospitalized in the Intensive Care Unit(Derman Medical Publ, 2016) Resorlu, Mustafa; Aylanc, Nilufer; Adam, Gurhan; Eker, NebilAim: To assess thoracic CT findings in non -traumatic patients with respiratory distress hospitalized in the intensive care unit. Material and Method: Forty-three patients treated in the intensive care unit in our hospital in 20152016 were included in the study. Thorax CT images obtained from the radiology archive were assessed by two radiology specialists. Patients' clinical findings and laboratory results were documented from the patients' records. Results: Nine patients (20.906) were female and 34 (79.1 Bb) were male. Mean age was 71.19 15.4 (21-89) years. The most common findings in the mediastinum were vascular atherosclerosis, lymphadenomegaly, and pericardial effusion, while the most common parenchymal findings were parenchymal fibrotic changes, pulmonary nodule, and emphysematous aeration. The prevalence of pleural effusion was 53.506. Discussion: The presence of underlying neurological and cardiovascular diseases in particular and general condition impairment in patients hospitalized in the intensive care unit represents a risk for the development of respiratory system pathologies.Öğe Thrombosis of the inferior vena cava presenting with findings of radiculopathy(Elsevier Science Inc, 2016) Resorlu, Hatice; Koral, Lokman; Aylanc, Nilufer; Ozcan, Sedat[Anstract Not Available]Öğe Ultrasonography and computed tomography findings in pulmonary alveolar microlithiasis(Georg Thieme Verlag Kg, 2018) Resorlu, Mustafa; Toprak, Canan Akgun; Aylanc, Nilufer; Karatag, Ozan[Anstract Not Available]Öğe Which is the most affected muscle in lumbar back pain multifidus or erector spinae?(Int Scientific Information Inc, 2020) Ozturk, Piril Erbay; Aylanc, NiluferPurpose: The purpose of this study is to evaluate the relationship between lumbar back pain, lumbar disc herniation, and erector spinae and multifidus muscle lipomatous degeneration. Material and methods: After receiving approval from the clinical studies Ethics Committee, magnetic resonance imaging (MRI) studies of patients who had physical examination in orthopaedic, neurology, neurosurgery, physical medicine and rehabilitation clinics were evaluated. Their pre-diagnoses were 'herniated nucleus pulposus' or 'lumbar disc herniation' or 'back pain' and their age range was between 18 and 64 years. Patients who had vertebral fracture, spondylitis-spondylodiscitis, tumours, structural anomalies such as spondylolisthesis, scoliosis and vertebral segmentation anomalies and previous surgery in the lumbar area were excluded. There were 205 patients in the case group who had lumbar disc herniation between L1-S1 level and there were 187 patients in the control group who had no lumbar disc herniation. In the study, patient age, sex, herniation level and erector spinae and multifidus muscle lipomatous degeneration were compared. Muscle lipomatous degeneration were evaluated with a visual scale. Results: There were 105 men and 100 women in the case group and 88 men and 99 women in the control group. In the case group, lumbar disc herniation was detected mostly at L4-5 and L5-S1 levels. There was no significant difference between case and control groups with regard to erector spinae and multifidus muscle lipomatous degeneration. In the case group, lipomatous degeneration of the erector spinae was higher compared to that of the multifidus muscle. Conclusions: Patients with low back pain may have fatty degeneration in erector spina and multifidus muscles with or without LDH, but LDH accelerates this process rather than being a result of it. In patients with LDH, fatty degeneration in the erector spina is more pronounced than in multifidus, and the erector spina is more affected by the LDH process.
