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    A Bibliometric Analysis Study of Global Academic Articles on Malaria and Contribution of Türkiye
    (Ordu University, 2024) Aydemir, Selahattin; Diril, Halit; Alkan, Sevil; Barlık, Fethi; Ekici, Abdurrahman
    Objective: Malaria is a parasitic infection that has a significant negative influence on public health around the world, including Türkiye in recent years with the prevalence of imported cases. This study was conducted to provide a bibliometric analysis of publications on malaria in Türkiye and worldwide, and to determine Türkiye's current position in malaria research. Methods: This study was observational, descriptive, and retrospective designed study and utilized scientometric technique and scientific mapping. The research was conducted in the Web of Science online database. The MESH keywords (malaria OR plasmodium) were used. The title (TI) field and only Science Citation Index Expanded (SCI-E) index was used for the search queries. The following inclusion and exclusion criteria were applied: The studies published after the end of 2022 were excluded and only the articles were chosen according to the document type. Results: On the basis of the defined search, 31376 articles were extracted from the WoS database indexed in the SCI-E category, for the period 1970-2022. The earliest article was published in 1970 and the most of the articles were published in 2021 (n=1274). There was a growth in publications number since end of the 1970s. A total 469 countries contributed the malaria literature. The United States of America (USA) (32.07%), England (18.56%) and France (9.90%) were the leading countries on the malaria literature according to the published article numbers. Türkiye ranked in 71st. A total of 80 articles were retrieved according to search criteria. The articles were cited 1347 times totally and 17.75 times per article. The mean of H index was 18. The earliest articles were published in 1987. The number of articles limited but since 2005 never dropped below two articles per year. Conclusion: Scientific production from Türkiye is low. This topic can be improved by increasing both the financial support for and the involvement of researchers in national and international collaborative research projects.
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    Bibliometric analysis of neurocysticercosis case reports and evaluation of presented cases
    (Academic Press Ltd- Elsevier Science Ltd, 2025) Gurbuz, Esra; Aydemir, Selahattin; Barlik, Fethi; Saygin, Murat; Yildiz, Rahmi; Alkan, Sevil; Ekici, Abdurrahman
    Neurocysticercosis (NCC) has been classified as a neglected tropical disease by the World Health Organization (WHO), with the condition being regarded as the most significant parasitic disease affecting the nervous system. Hence, the aim of this study was to conduct a review of previously published case reports on this topic in order to ascertain whether there is an increasing trend of NCC worldwide and evaluate the cases that have been presented. After a comprehensive search of the Web of Science Core Collection using the keywords neurocysticercosis and case reports, studies were selected by applying inclusion criteria. Important data attributes that were extracted in plain text format included the document titles, publication years, journal names, author(s) name(s), keywords, institutions, and countries. In addition, to evaluate the cases, the age and gender of the patients, complaints on admission, localization of the cyst, and treatment procedure used were recorded in an Excel file. The bibliometric analysis was conducted using Biblioshiny. Additionally, GraphPad and Excel were employed for the creation of graphical representations. The dataset analyzed included 297 documents, 162 from various sources, with an average age of 12.2 years and 6.3 citations per document. The number of case reports tended to increase over the years. India and the USA were the leading contributors to NCC case reports, with 78 (26.3 %) and 64 (21.5 %), respectively. This was followed by Brazil, France, and Spain with 31 (10.4 %), 14 (4.7 %) and 13 (4.4 %) case reports, respectively. Moreover 55.5 % of the patients in the cases presented in the articles were male and 12.9 % were in the 21-25 age group. In regard to the cysts, 81.2 % were located in the brain and 15.1 % were in the spine. The most common complaints were headache and seizures in brain localized NCC cases and back pain and numbness or weakness in extremities in spine localized NCC cases. Albendazole was used in 174 (54.5 %) cases, praziquantel in 22 (6.9 %) cases, and ivermectin in five (1.6 %) cases. In conclusion, NCC continues to be an increasingly serious public health problem in India as well as developed countries such as the USA and European countries. NCC can be seen in all age groups, males are more susceptible than females, cysts are more localized in the ventricular system, and albendazole and/or paraziquentel are used in treatment. In addition, more comprehensive studies on the use of ivermectin in the treatment of NCC should be conducted, as success was achieved in cases where ivermectin was used in treatment.
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    Bibliometric assessment of Thelaziosis research in Europe from 1970-2023
    (University of Tabriz, 2023) Tahmaz, Alper; Alkan, Sevil; Aydemir, Selahattin
    Given the increase in cases of thelaziosis in recent years, especially in Europe, we evaluate the publication patterns of research focusing on Thelazia. We also discuss the results of published articles and how more clinical and epidemiological information on Thelazia is still needed. All the documents registered in Web of Science with the subject of Thelazia between 1970 and 31 March 2023 were analyzed, using the Online Analysis Platform of Literature Metrology and the VOS viewer as tools. Between 1970 and March 2023, there were 336 publications on Thelazia. During the same period, these documents were mentioned 5597 times, averaging 16.66 times for each record. Thelazia's first publications appeared in 1970, and 55.95% of all publications were published after 2010. Regarding total publication numbers, the most influential country was Italy (n = 87), followed by the United States (n=57). The most prolific author in this field was "Domenico Otranto" (n = 77), while the journals that drew the most papers were Parasites & Vectors (n = 30) and Veterinary Parasitology (n = 29). The findings of this article will be useful in defining research priorities related to Thelazia and diagnosing the importance of scientific production associated with this pathogen. © 2023, Published by University of Tabriz.
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    Investigation of publication trends and hot topics on onchocerciasis between 2000 and 2022
    (University of Tabriz, 2023) Alkan, Sevil; Gürbüz, Esra; Aydemir, Selahattin
    This study aimed to use bibliometric tools to investigate onchocerciasis research conducted worldwide between 2000 and 2022. This bibliometric study was carried out using the Scopus database. The analysis unit was the documents conducted on onchocerciasis between 2000 and 2022. The data obtained after the last evaluations were transferred to VOSviewer (VOSviewer 1.6.19 for Microsoft Windows systems) and biblioshiny (bibliometrix R package) programs for analysis. The present results showed that 1026 documents on onchocerciasis were indexed in the Scopus database between 2000 and 2022. 2554 authors have published this literature, and the annual growth rate was 1.34 %. Forty-one articles were published in 2000, and after 2014, there was an increase in the number of articles. The most publications were published in 2018 (n = 82). PLOS Neglected Tropical Diseases (n = 97) and Parasites & Vectors (n = 46) published the most publications on onchocerciasis. Most of the publications were published by authors from the United States (n = 341), the United Kingdom (n = 228), Cameroon (n = 150), Nigeria (n = 132), and Germany (n = 120). The documents originating from the United States (n = 2372) had the highest citation numbers. The onchocerciasis research landscape between 2000 and 2022 is outlined in this report. Furthermore, the analysis offers an enhanced comprehension of the trends in onchocerciasis development over the previous 23 years, which might serve as a scientific benchmark for subsequent research. © 2023, Published by University of Tabriz.
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    Molecular Characterization of Giardia intestinalis and Cryptosporidium spp. Detected in Humans in Ağrı, Türkiye
    (Iranian Scientific Society Medical Entomology, 2024) Aydemir, Selahattin; Barlik, Fethi; Ekici, Abdurrahman; Barlik, Dilara Hande; Alkan, Sevil; Gurbuz, Esra; Yilmaz, Hasan
    Background: We aimed to determine the prevalence of Giardia intestinalis and Cryptosporidium spp. in patients who admitted hospital with diarrhea and to gain information about the transmission of these parasites in Agri, Turkiye. Methods: This study included 184 patients who applied to Agri-Diyadin State Hospital, Turkiye in 2022. The immunochromatographic card test was used for detection of the G. intestinalis and Cryptosporidium spp. Nested PCR-RFLP analysis of the COWP gene and sequence analysis of the gp60 gene were used to genotype and subtype Cryptosporidium spp., whereas Nested PCR and sequence analyses of beta-giardin gene were used genotype G. intestinalis. Results: Of the 184 stool specimens examined, 12 (14.29%) and 7 (3.80%) were positive for G. intestinalis and Cryptosporidium spp., respectively. The Cryptosporidium species were identified as C. parvum belonging to the IId subtype family. The G. intestinalis were identified assemblages A. Conclusion: Assemblage A, which is associated with diarrhea, is responsible for giardiasis and C. parvum IId subtype, often found in sheep, goats and cattle, is responsible for cryptosporidiosis in Agri, Turkiye.
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    Relationship of Demodex Mites in Immunodeficiency, Rocesea, Blepharitis and Some Clinical Findings
    (Ordu Üniversitesi, 2022) Akkaş, Önder; Aydemir, Selahattin; Gürbüz, Esra; Coşkun, Sadeddin; Ekici, Abdurrahman; Halidi, Ahmed Galip; Çeviker, Sevil Alkan
    Objective: Demodex folliculorum and Demodex brevis are two species known to settle on the skin of humans. Demodex mite infections are called demodicosis. Demodicosis, which is usually asymptomatic, is known to cause some skin diseases as a result of an imbalance in immune system mechanisms This study was conducted to investigate the relationship between Demodex spp. infestations and clinical signs, such as immunodeficiency, rosacea, blepharitis and facial itching, facial flushing, facial tenderness, facial rash, and sunburn.Methods: A total of 350 patients, 178 of whom were immunosuppressed and 172 who were immunocompetent, were included in the study. Samples were taken from the nose, chin, and forehead areas, using the standard superficial skin biopsy method and were examined under a microscope.Results: Demodex spp. was detected in 224 of the 350 patients, including 144 (80.90%) of the 178 immunosuppressed patients and 88 (51.16%) of the 172 immunocompetent patients included in the study. The difference between Demodex spp. positivity in the immunosuppressed patients and positivity in the immunocompetent patients was statistically significant. In addition, a relationship was found between Demodex spp. and some clinical symptoms.Conclusion: Demodex spp. proceed a health problem in rosacea and immunosuppressed patients. It was concluded that Demodex spp. should definitely be considered in cases of facial sensitivity, facial rash, and facial flushing in both immunosuppressed and immunocompetent patients, especially in the presence of sunburn in immunosuppressed patients, which was revealed by this study.
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    Trends in Anisakis simplex Global Research: A Bibliometric Analysis Study
    (Galenos Publishing House, 2024) Aydemir, Mehmet Emin; Aydemir, Selahattin; Kılıç Altun, Serap; Alkan, Sevil
    Objective: Anisakis simplex is a fish-borne zoonotic parasite. Although this parasite has been known since the 19th century, publications on anisakiasis have increased in recent years. Despite this, this subject has yet to be well studied by bibliometric analysis. This study was conducted to show the research points and trends of A. simplex. Methods: The Web of Science Core Collection (WoSCC) was mined for articles on A. simplex. The VOSviewer software visually evaluated countries, institutions, authors, references, and keywords in this field. Results: A total of 1362 publications were included in this bibliometric analysis. The included publications were published between 1970 and 2022 from 79 countries, mainly from Spain (n=456, 33.48%). The most prolific year was 2020 (n=74). The research area that attracted the most publications was parasitology (n=452), while the most productive author in this area was Cuellar C (n=53). “Anisakis simplex”, “Anisakis” and “anisakiasis” were the most used three keywords. Conclusion: The number of publications on anisakiasis has been increasing over time, suggesting that A. simplex is becoming an increasingly important disease worldwide. Research cooperation should be established between researchers from developed and developing countries to determine effective control strategies for anisakiasis. © 2024 Turkish Society for Parasitology.
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    Trends in Naegleria fowleri global research: A bibliometric analysis study
    (Elsevier, 2022) Ekici, Abdurrahman; Alkan, Sevil; Aydemir, Selahattin; Gurbuz, Esra; Unlu, Ahmet Hakan
    Naegleria fowleri is one of the most dangerous protozoan agents. This article describes a bibliometric review of the literature on N. fowleri research indexed in WoS during a 51-year period. The VOSviewer visualization meth-odology was used to conduct a bibliometric study. The data included articles from the Web of Science database, nations, institutions, journals, keywords, co-authorship, co-citations, international collaborations, and citation rates. A total of 1106 articles were retrieved from the Web of Science database. The articles were cited 21,904 times in total (cited 12,138 times without self-citations). The average citation per article was 19.82. The Hirsch index was 63. The leading country according to the number of published articles was the United States of America (USA) (n = 447; 40.416%), followed by Mexico (n = 80; 7.233%), and Australia (n = 63; 5.696%). Other than these top three countries, the publications were from 74 countries globally. Especially after the 2000s, both the number of citations and the number of publications exhibited an increasing trend. The Virginia Common-wealth University (USA) (9.584%), Centers for Disease Control Prevention (USA) (8.770%), and Instituto Poli-tecnico Nacional Mexico (4.069%) were the leading affiliations. Most of the leading affiliations were from the USA and Mexico. In conclusion, a bibliometric evaluation of N. fowleri was performed for the first time. Authors affiliated with institutions in the USA and Mexico have led scientific production on PAM. Efforts should be made to help developing countries with the highest prevalence of N. fowleri to develop scientific research networks with the USA and/or Mexico in order to increase research with interdisciplinary teams.