Yazar "Aydemir, Ferhan Demirer" seçeneğine göre listele

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    ICU admission delays: Impact on length of stay and long-term outcomes
    (Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, 2026) Aydemir, Ferhan Demirer; Kurtkulagi, Ozge; Ergun, Bisar; Bayrak, Vecihe; Oner, Ozlem; Comert, Bilgin; Gokmen, Ali Necati
    Delays in intensive care unit (ICU) admissions are prevalent in overcrowded hospitals and can adversely affect patient outcomes. However, the extent of this impact, particularly beyond short-term mortality, remains unclear. We hypothesized that ICU admission delays exceeding 6 hours after consultation would independently increase 90-day mortality and prolong ICU length of stay. We conducted a retrospective analysis of data from 273 adult patients admitted to the ICU of a tertiary university hospital between January and December 2019. Patients were stratified into two groups: early admission (<= 6 hours) and delayed admission (>6 hours). Multivariate Cox regression was employed to identify independent predictors of mortality. Delayed ICU admission was observed in 72.8% of patients. Although delayed admission was not independently associated with increased mortality in the multivariate analysis (HR: 0.88; 95% CI: 0.61-1.27), it was significantly correlated with prolonged ICU length of stay and higher 90-day mortality in the univariate analysis (p = 0.039), with no significant difference in vasopressor-free days (p = 0.809). In our assessment of independent mortality predictors, we found that patients with higher APACHE-II and Charlson scores experienced longer delays in ICU transfer. Additionally, respiratory and circulatory failure at admission were independently associated with increased mortality (HR: 2.17; 95% CI: 1.51-3.12). While early ICU admission did not independently predict mortality, it was linked to extended ICU stays, an increased treatment burden, and adverse long-term outcomes. These findings underscore the necessity of refining triage processes and evaluating baseline patient severity when interpreting the impact of ICU admission timing on outcomes.
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    The effect of Lymphocyte Monocyte Ratio (LMR) on 30-day mortality of non-HCC post-transplant liver patients admitted to the intensive care unit
    (Dicle University, 2025) Bayrak, Vecihe; Gürkök, Mehmet Çağatay; Ağalar, Cihan; Unek, Tarkan; Aydemir, Ferhan Demirer; Veziroğlu, İrem Erdoğan; Gökmen, Necati
    Aim: Our study aims to investigate the effect of the LMR value on the 30-day mortality and intensive care hospitalization days of post-transplant liver patients without hepatocellular cancer(HCC) admitted to the intensive care unit(ICU). Methods: Our retrospective study included post-liver transplant patients in the ICU of Dokuz Eylul University Hospital between 2010 and 2020. We recorded patients' age, gender, aetiology of liver disease, donor type (living or deceased), duration of cold ischemia, scores, hospitalization days in the ICU, and 30-day mortality. LMR was calculated by dividing the patient's lymphocyte count by the monocyte count. Statistical analyses were performed using SPSS software version 24.0. Results: 128 (92 male, 36 female) patients were included in our study. Twenty-four patients died within 30 days. The mean LMR was 1.498±2.134, and no significant difference existed between those with and without 30-day mortality (p=0.995). LMR value was not a predictor of mortality and ICU hospitalization days in these patients. Conclusion: Our study revealed that LMR does not predict mortality or hospitalization days in post-liver transplant patients without HCC. The results of our study and previous studies suggest that LMR alteration is associated with an immune state produced by the tumour microenvironment. Our findings suggest that LMR may not be a valuable biomarker for predicting patient outcomes in post-liver transplant patients without HCC. However, this study provides a starting point for further investigation into the role of LMR in cancer diseases.