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Öğe Epicardial Adipose Tissue Is Increased in Patients With Inflammatory Bowel Disease(Amer Inst Ultrasound Medicine, 2016) Uysal, Fatma; Akbal, Erdem; Akbal, Ayla; Cevizci, Sibel; Arik, Kasim; Gazi, EmineObjectives-Patients with inflammatory bowel disease (IBD) have high cardiovascular morbidity, and, in general, epicardial adipose tissue thickness is related to atherosclerotic vascular disease. This study aimed to investigate the association between epicardial adipose tissue thickness and carotid intima-media thickness as markers of early atherosclerosis in patients with IBD. Methods-The study comprised 47 patients with IBD (25 with Crohn disease and 22 with ulcerative colitis) and 35 control participants. In all individuals, epicardial adipose tissue and carotid intima-media thickness values were measured by sonography. Results-The mean age +/- SD of the 47 patients with IBD was 42.3 +/- 11.2 years, versus 41.4 +/- 10.1 years for the control group. The epicardial adipose tissue thickness was higher in both the Crohn disease and ulcerative colitis groups compared to the control group (P < .001), but not the carotid intima-media thickness (P = .695 and .917, respectively). There was a strong positive correlation between the carotid intima-media and epicardial adipose tissue thickness values in the Crohn disease and ulcerative colitis groups (r = 0.757; 95% confidence interval, 0.711-0.901; r = 0.786; 95% confidence interval, 0.364-0.615; both P < .001). However, there was no significant difference between the patients who were in the active and inactive disease periods in both groups in terms of carotid intima-media and epicardial adipose tissue thickness values. Conclusions-Our findings suggest that epicardial adipose tissue thickness might be a marker for detection of early atherosclerosis in patients with IBD. There was a strong positive correlation between carotid intima-media thickness and epicardial adipose tissue thickness values in the patients with IBD. However, there was no correlation between IBD activity and carotid intima-media or epicardial adipose tissue thickness.Öğe EVALUATION OF EPICARDIAL FAT TISSUE THICKNESS AND CAROTID INTIMA MEDIA THICKNESS IN PATIENTS WITH PRIMARY HYPERPARATHYROIDISM AFTER PARATHYROIDECTOMY(Carbone Editore, 2017) Eroglu, Mustafa; Ozkul, Faruk; Erbag, Gokhan; Temiz, Ahmet; Altun, Burak; Arik, Kasim; Sen, HacerIntroduction: It has been shown that epicardial fat tissue (EFT) thickness in primary hyperparathyroidism (PHPT) is increased and that this is closely associated with cardiovascular disease and atherosclerosis. However, EFT thickness in patients with hyperparathyroidism who were treated with parathyroidectomy has not yet been studied. In this study we aimed to examine whether carotid intima-media thickness (CIMT) and EFT thickness would be affected after treatment of PHPT by parathyroidectomy. Materials and methods: 27 patients with PHPT who were diagnosed with a parathyroidectomy indication and 39 healthy volunteers were included in the study. For all patients with PHPT, anthropometric measurements were made before and 12 months after parathyroidectomy, and EFT thickness, CIMT, serum parathormone (PTH), calcium and lipid levels were measured. Results: It was observed that preoperative CIMT and EFT thickness in patients with PHPT were significantly higher than the control group (for both p<0.001). Although hyperparathyroidism and hypercalcemia of the patients improved after parathyroidectomy, no significant change in the thickness of CIMT or EFT was determined. Conclusions: CIMT and EFT thickness seem to be good cardiovascular indicators for diagnosis of patients with PHPT. Nevertheless, this study raises the question of the reliability of a decrease in these parameters in patient follow-up. It is therefore necessary to be more careful in evaluating these parameters after treatment of patients with PHPT.Öğe Musculoskeletal System Injuries Due to Motorcycle Accidents in Aksaray(Elsevier, 2013) Komurcu, Erkam; Arik, Kasim; Golge, Umut Hatay; Nusran, Gurdal; Kurt, TolgaObjectives An increase in motorcycle accidents and injuries has been observed in recent years due to the rising number of motorcyclists. The purpose of our study was to evaluate musculoskeletal system injuries due to motorcycle accidents. Methods The files of 189 patients who presented at the Aksaray State Hospital Emergency Service with injuries due to motorcycle accidents were investigated retrospectively. Age, gender, and current trauma were recorded for each patient. Cases with musculoskeletal system injuries were evaluated according to site of injury, and subsequent morbidity and mortality were documented. Results Of the 189 patients, 168 were male (89.9%), and 21 were female (11.1%). Locomotor system injuries were present in 147 patients (77.8%). The number of patients presenting with multiple extremity injuries versus isolated extremity injuries were 26 (17.69%) and 70 (47.62%), respectively. Soft tissue trauma was present in only 51 patients (34.69%). The distribution of fractures and dislocations was as follows: 74 (54.81%), lower extremity; 48 (35.56%), upper extremity; 9 (6.67%), pelvic; and 4 (2.96%), vertebral injuries. Of the extremity injuries, injuries to the femur (27.41%) and tibia (19.26) were most prevalent, followed by hand and wrist (9.63%) injuries. Seven patients with multiple organ injuries died, while permanent disability due to extremity function loss occurred in 22 patients. Pulmonary embolism and osteomyelitis complications occurred in two patients and one patient, respectively. Injuries were reported most frequently in July between 23: 00 and 03:00 and 04:00 and 07:00. According to the records, 48 (32.79%) of the patients with musculoskeletal injuries were drunk. Conclusions Musculoskeletal system injuries due to motorcycle accidents cause lifelong disabilities. To reduce the frequency of accidents, social awareness should be increased, and training programs in motorcycle usage should be more effective and widespread.Öğe Protective Effect of Possible Olive Oil, Olive Leaves and Olive Seeds on Ethanol Induced Experimental Ulcer Model in Rats(Wiley-Blackwell, 2015) Vural, Zehra; Kahraman, Mustafa; Sehitoglu, Hilal; Vural, Ahmet; Arik, Kasim; Simsek, Tuncer; Cetiner, Sule[Anstract Not Available]Öğe Severe hyperparathyroidism in patient with right thyroid hemiagenesis(Pakistan Medical Assoc, 2015) Eroglu, Mustafa; Ozkul, Faruk; Barutcu, Ebru Cakan; Arik, Kasim; Adam, Gurhan; Bilen, Yildiz; Ukinc, KubilayThyroid hemiagenesis is an infrequent congenital disorder which is rarely associated with hyperparathyroidism. We present a case of an adult woman who presented with hyperparathyroidism and ipsilateral thyroid hemiagenesis. Parathyroid adenoma was excised by minimal invasive parathyroidectomy.
