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    Contribution of spirometry to early diagnosis of chronic obstructive pulmonary disease in primary health care centers
    (Tubitak Scientific & Technological Research Council Turkey, 2013) Erdoğan, Aysel; Ucar, Elif Yilmazel; Araz, Omer; Sağlam, Leyla; Mirici, Nihal Arzu
    Aim: Chronic obstructive pulmonary disease (COPD) is a common disease with increasing prevalence and mortality. We aimed to determine COPD prevalence in primary health care centers. Materials and methods: Pulmonary function tests (PFTs) and face-to-face interviews were administered to 500 patients older than 40 years of age and attending a primary health care center with any symptoms. An early reversibility test was performed on patients with a forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio below 70%. The survey results, PFTs, and early reversibility test results were evaluated according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria. All parameters were compared for groups with and without COPD. Results: COPD was diagnosed in 25 (5%) of the patients. Of these patients, 60% were female and 40% were male. According to GOLD guidelines, 48% of the patients had mild COPD, 36% of them had moderate COPD, and 16% of them had severe COPD. According to their history and physical examination, 72 (14.4%) participants had been previously suspected of having COPD. PFTs revealed that 59 of them did not have COPD. Conclusion: The utilization of spirometers in primary health care centers is important both for early diagnosis and to prevent misdiagnosis of COPD.
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    Medical Image: Silicosis due to denim sandblasting: Multidetector CT findings
    (2008) Akgun, Metin; Kantarci, Mecit; Araz, Omer; Ucar, Elif Yilmazel; Mirici, Arzu
    [No abstract available]
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    Nutritional assessment via anthropometric and biochemical measurements with stable COPD
    (Tubitak Scientific & Technological Research Council Turkey, 2012) Meral, Mehmet; Araz, Omer; Yilmazel Ucar, Elif; Yilmaz, Nusret; Mirici, Nihal Arzu
    Aim: Nutritional assessment is important for the management of chronic obstructive pulmonary disease (COPD). This study aims at investigating the relation between the anthropometric and biochemical parameters for nutritional assessment with pulmonary function tests in COPD. Materials and methods: This is a prospective, cross-sectional study. Thirty-nine patients with stable COPD were enrolled the study. We evaluated the anthropometric [body mass index (BMI), skinfold thickness (SFT), and arm muscle circumference (AMC)), biochemical [serum total protein, albumin, transferrin, and blood urea nitrogen (BUN)], and spirometric [forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), and FEV1/FVC] measurements, as well as the correlations among them. Results: There was a significant positive correlation between BMI and the other anthropometric parameters. There was no statistically significant correlation between the spirometric measurements and the biochemical parameters. We detected a positive correlation between SFT and serum albumin and total protein, and a negative correlation between BUN and AMC. Conclusion: Anthropometric and biochemical parameters may be used for nutritional assessment and nutritional support as criteria in stable COPD patients.
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    Öğe
    Silicosis due to denim sandblasting: multidetector CT findings
    (New Zealand Medical Assoc, 2008) Akgun, Metin; Kantarci, Mecit; Araz, Omer; Ucar, Elif Yilmazel; Mirici, Arzu
    [Anstract Not Available]
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    The diagnostic value of bronchoscopy in smear negative cases with pulmonary tuberculosis
    (Turkish Assoc Tuberculosis & Thorax, 2008) Araz, Omer; Akgun, Metin; Saglam, Leyla; Ozden, Kemalettin; Mirici, Arzu
    There are many studies showing usefulness of bronchoscopy in patients with suspected pulmonary tuberculosis (Tbc) and negative sputum smear. However, there is no enough data concerning that in which cases bronchoscopy is more useful. We aimed to investigate in which cases bronchoscopy is more diagnostic and also an in which cases presence of endobronchial involvement is more likely. A total of 60 smear negative patients undergoing bronchoscopy due to tuberculosis suspicion were evaluated. The characteristics of cases with or without positive diagnosis via bronchoscopy and also of the ones with or without endobronchial involvement were compared. Bronchoscopy provided positive result for Tbc in 29 (76%) of 38 cases with confirmed as Tbc later and 7 (18%) cases had endobronchial involvement. In the cases who are diagnosed as Tbc via bronchoscopy, the mean serum levels of C-reactive protein (CRP) were significantly higher than those of undiagnosed (p< 0.05). In the cases with endobronchial involvement, the duration of symptoms was significantly shorter (p= 0.01); the diameter of tuberculin skin test induration was significantly smaller (p< 0.05); and mean serum level of CRP was significantly higher (p< 0.05) than those of without endobronchial lesion. The results suggest that it is more likely to diagnose Tbc bronchoscopically in the cases who had increased serum levels of CRP, and possibility of endobronchial involvement may be increased among the cases in active and earlier period of the disease. However, further studies are required to support this hypothesis.
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    The incidence and severity of pulmonary hypertension in obstructive sleep apnea with hypothyroidism
    (Int Scientific Literature, Inc, 2013) Araz, Omer; Ucar, Elif Yilmazel; Yalcin, Aslihan; Pulur, Didem; Acemoglu, Hamit; Tas, Hakan; Saglam, Leyla
    Background: Hypothyroidism and obstructive sleep apnea (OSA) are both common health problems and can be seen together. Each of these 2 diseases can cause pulmonary hypertension (PH). We aimed to determine whether hypothyroidism with OSA has a significant effect on the frequency and severity of PH. Material/Methods: A total of 236 patients were included in the study. Patients were divided into 3 groups: Group I, Obstructive Sleep Apnea (n=149); Group II, Hypothyroidism (n=56); and Group III, Obstructive Sleep Apnea-Hypothyroidism (n=31). All patients underwent polysomnography and echocardiography and serum levels of thyroid-stimulating hormone (TSH) and free thyroxine 4 (FT4) were analyzed. Results: There were 167 male and 69 female participants, and the mean age was 47.8 +/- 11.5 (Group I: 81.9% male, 18.1% female; Group II: 44.6% male, 55.4% female; Group III: 64.6% male, 35.4% female). Distribution of mean pulmonary arterial pressure on echocardiography was statistically different among the 3 groups (x(2)=14.99, p=0.006). When adjusted according to the apnea-hypopnea index (AHI), age, and body mass index (BMI), a significant relation with PH was determined (p=0.002). Conclusions: The combination of hypothyroidism with OSA is associated with an increased frequency and severity of PH. When PH is found out of line with the severity of OSA, thyroid dysfunction should be investigated.