Yazar "Altinisik, Hatice Betul" seçeneğine göre listele
Listeleniyor 1 - 9 / 9
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe A practical approach in difficult intubation: use of gum elastic bougie on 10 cases(Yerkure Tanitim & Yayincilik Hizmetleri A S, 2016) Altinisik, Ugur; Erbas, Mesut; Kiraz, Hasan Ali; Simsek, Tuncer; Altinisik, Hatice Betul; Turk, Fatos Ipek; Toman, HuseyinObjective: When faced with unexpected difficult intubation, despite all the technological advances, there is still a need of equipments that are easy to use and very reachable. In this study, we offer our experiences in use of gum elastic bougie in 10 cases with unexpected difficult intubation in our operation rooms. Material and Methods: In Canakkale 18 March University Medical Faculty's Operating Rooms and between the years 2013-2014, all the encountered unexpected difficult intubation cases are classified and the patients who has Mallampati score I-II and having any airway pathology evaluated for the use of Gum elastic bougie (GEB). Auxiliary equipments used in intubation, number of intubation attempts, number of anesthesiologists who tried for intubation, the number of trials with GEB and the complications due to the use of GEB were recorded. Results: A total of 10 cases with unexpected difficult intubation were included in the study. All of the cases were male and intubation was attempted with size 4 blades. Stylet in 6 cases, fast trach laryngeal mask in 1 case were used after unsuccessful intubation attempts. However the use of this equipments patients couldn't be intubated and after at least 3 three attempts GEB used this time for intubation. An experienced anesthesiologist with the help of GEB intubated all the patients at once. There were no complications related to the use of GEB. Conclusion: GEB is widely used in European countries for unexpected difficult intubation. In our patients, despite the absence of any complications, due to the blind insertion of bougie trauma cases have been reported. GEB when performed by an experienced anesthesiologist is a good alternative airway equipment in unexpected difficult airway management, because it's inexpensive, easy to use and portable.Öğe Clinical Characteristics of Patients Diagnosed with Synthetic Cannabinoid (Bonsai) Intoxication in Intensive Care Unit(Galenos Yayincilik, 2015) Altinisik, Ugur; Altinisik, Hatice Betul; Simsek, Tuncer; Dogu, Tugba; Simsek, Esen; Aydin, HalideObjective: In recent years, synthetic cannabinoids (bonsai) poisoning is a widely seen case that needs to be treated in intensive care unit (ICU) in our country. In this study, it was aimed to discuss the clinical characteristics of patients diagnosed with synthetic cannabinoid intoxication followed in ICU. Material and Method: Patients followed in ICU of Canakkale Onsekiz Mart University and Canakkale State Hospital between 2014 and 2015 were studied retrospectively. Results: Twelve cases were included. In neurological system; confusions (n=4), drowsiness (n=7), restlessness/agitations (n=5), hallucinations (n=2), anxieties/panics (n=3), acute psychosis (n=1) and amnesias (n=11) were detected. One patient was intubated. In cardiovascular system; tachycardias (n=3), bradycardias (n=2), hypertensions (n=2), hypotension (n=1), and arrhythmias (n=2) were observed. In laboratory tests, leukocytosis (n=4), leukopenia (n=1), hypoglycemias (n=3), elevation in liver and renal function tests (n=1) were identified. The average recovery time was 19.3-hours and the average ICU stay was 3-days. Conclusion: In the synthetic cannabinoid intoxication cases; it should be kept in mind that seizure activities may occur in the first hours, myocardial infarction risk in the first 3-days. Liver-kidney functions should be monitored. Hypopotasemia is the most common electrolyte disorder. Cases without any complication are expected to recover in 24-hours. However, new types of synthetic cannabinoids are put on the market every day.Öğe Comparing the effect of two different induction regimens with thiopental on hemodynamics during laryngoscopy and tracheal intubation in hypertensive patients(Anaesthesia Pain & Intensive Care, 2018) Ural, Sedef Gulcin; Yazicioglu, Dilek; Simsek, Tuncer; Erbas, Mesut; Sahin, Hasan; Altinisik, Hatice BetulObjective: Inj thiopental is known to result in hypotension during induction, and the effect is more pronounced in hypertensive patients. This study aimed to compare the effect of two different anesthesia induction regimens with pentothal in managing the hemodynamic response to laryngoscopy and endotracheal intubation in known hypertensive patients. Methodology: The study was conducted in Van Educational Research Hospital in 2014 after approval from the ethics committee and informed consent from patients were obtained. The prospective, double-blind, randomized study included the American Society of Anesthesiologists (ASA) grade II-III 90 patients, aged 40-65 y, scheduled for elective abdominal surgery with general anesthesia. Thiopental (3-7 mg/kg) was given to the patients in Group 1 (n = 45) with single dose injection in 20 s. In Group 2 (n = 45), first 75% of the thiopental dose was given, and after the bispectral index- based scale (BIS) value was < 60 and after injecting neuromuscular blocking agent, the rest of the thiopental dose was added and injection duration was recorded. In both groups, midazolam 0.05-0.1 mg/kg was administered for premedication. Fentanyl and rocuronium were used in both groups to complete induction. During the first 25 min, systolic arterial pressure, diastolic arterial pressure, mean arterial pressure, and heart rate of the patients were recorded. Also, BIS values after induction and total additional fentanyl requirement were recorded. Results: Heart rate, mean arterial pressure, and additional fentanyl requirement was significantly lower in Group 2. BIS values were also lower in Group 2. Induction duration was higher in Group 2, but hemodynamic control was more satisfying. Conclusion: The study indicated that injection of thiopental in divided doses is more comfortable and safe when considering hemodynamic instability during anesthesia induction in hypertensive patients.Öğe Effects of preoperative smoking cessation on HAM-A sedation scores and intraoperative consumption of anesthetics and fentanyl(Anaesthesia Pain & Intensive Care, 2017) Ural, Sedef Gulcin; Yazicioglu, Dilek; Sahin, Hasan; Altinisik, Ugur; Dogu, Tugba; Altinisik, Hatice Betul; Ozmen, MustafaObjective: Patients undergoing surgery, experience acute physiological distress in the preoperative period. Smoking addiction is a complex behavior in which environment and genetic effects play a part. In this study our aim was to compare the impact of cigarette smoking cessation verses continued smoking on preoperative HAM-A scores and anesthetic requirement Methodology: After approval by the Ethic Committee, informed consent was obtained from patients, 1865 years old, American Society of Anesthesiologists (ASA) physical status I-II, 120 patients scheduled for elective laparoscopic cholecystectomy were included in this prospective randomized, double-blind study. Groups were defined as Group N (n:60, patients who continued smoking in the preoperative period) and Group NS (n:60, who stopped smoking 48 hours before the operation). Only the first patient on the list were included... All patients received intravenous midazolam 0.05-0.1 mg/kg as premedication. In the preoperative period HAM-A scores were recorded while the preoperative examination was performed in the outpatient clinic and after premedication. In addition, we monitored patients with Bispectral Index Monitor (BIS) and anesthetic requirements were recorded during surgical procedure. Results: HAM-A scores in the outpatient clinic and after receiving premedication were statistically significantly higher in Group N. Additional fentanyl requirement was also significantly higher in Group N. Conclusion: We conclude that to stop smoking 48 hours before surgery reduced anxiety as measured by HAM-A scores and anesthetic requirement and increased patient comfort.Öğe Evaluation of Serum Creatinine Levels with Reference Change Value in Patients Receiving Colistin Treatment(Oxford University Press, 2023) Cinpolat, Havva Yasemin; Alkan, Sevil; Altinisik, Hatice Betul; Cakir, Dilek Ulker; Oguzman, HamdiObjective: In this study, we aimed to evaluate the serum creatinine (SCr) levels with the reference change value (RCV) in patients receiving colistin treatment. Methods: We retrospectively recorded the SCr levels of 47 patients receiving colistin treatment before treatment and on days 3 and 7 after treatment. RCV was calculated with the asymmetrical RCV formula (Z = 1.64, P <. 05). Percent (%) increase in the SCr results of the patients was compared with RCV and values exceeding RCV were regarded as statistically significant. Results: The RCV was calculated as 15.6% for SCr. Compared with pretreatment values, SCr value on day 3 was 32/47 and on day 7 it was 36/47; as these results exceeded RCV, they were considered statistically significant. Conclusion: Use of RCV in the interpretation of results between serial measurements will provide a more rapid and sensitive method when making decisions. © 2023 The Author(s).Öğe Evaluation of the Approaches of the Anaesthesiologists on Maintenance of Anaesthesia Machines(Aves, 2016) Altinisik, Ugur; Altinisik, Hatice Betul; Simsek, Tuncer; Kiraz, Hasan Ali; Dogu, Tugba; Toman, Huseyin; Sahin, HasanObjective: In this study, we aimed to discuss the level of knowledge and approach on 'maintenance, calibration and cleaning of anaesthesia devices' among anaesthesiologists in Turkey. Methods: A questionnaire was prepared with 21 questions based on the Google document system, and these questionnaires were sent to the anaesthesiologists via e-mail. Results: Overall, 226 anaesthesiologists answered our survey. With respect to the maintenance and calibration, anaesthesiologists had sufficient information about the vaporizer and the carbon dioxide canister devices; however, information about the vital components, such as disassembly of the anaesthesia machine, flow sensor, oxygen sensor, battery and exhaust system, was insufficient. The cleaning and sterilization procedures were performed when the devices became dirty, and the bacteria filter was used only for the protection of the anaesthesia system. There was a lack of knowledge about how and which part of the anaesthesia device should be disinfected. In total, 85% of the survey participants were thinking of the need of additional education on anaesthesia machine maintenance. Conclusion: It is observed that education about anaesthesia device maintenance, calibration and cleaning issues is obviously necessary for the anaesthesiology specialists in our country. We believe that it would be useful to highlight this issue to anaesthesia educational institutions and anaesthesia associations.Öğe Neutrophil-platelet ratio as a predictor of acute kidney injury in severe COVID-19(Lippincott Williams & Wilkins, 2024) Sayan, Mihrican; Altinisik, Hatice Betul; Sayan, OzanAcute kidney injury (AKI) is one of the most seen complications of coronavirus-2019 (COVID-19) infection. Patients with AKI caused by COVID-19 likely have higher neutrophil counts and lower platelet and lymphocyte levels. Therefore, the predictive value of many inflammation indexes calculated from the total blood count has been investigated to predict the AKI in COVID-19. According to our clinical experience, we thought that neutrophilia and thrombocytopenia may be more common in the development of AKI. For this reason, this study aimed to evaluate the predictive value of the neutrophil-to-platelet ratio (NPR) for AKI in severe COVID-19 patients. This retrospective study included 334 severe COVID-19 patients followed up in the intensive care unit (ICU). Predictive factors for AKI were analyzed. ROC curve analysis was performed to determine the inflammation indexes' cutoff values for the AKI prediction. Multivariate analyses were performed to determine correlations between the inflammation indexes and AKI. In this study, AKI was determined at the rate of 43% (n:145). Independent risk factors affecting AKI were determined to be age (HR = 1.047, 95% confidence interval [CI]: 1.021-1.072, P < .001), the need for invasive mechanical ventilation (HR = 3.003, 95% CI: 1.645-5.481, P = .001) and the need for vasopressor (HR = 8.111, 95% CI: 3.786-17.375, P < .001). The optimal cutoff values predicting AKI were determined to be 3.9 for the NPR (AUC = 0.679, 95% CI: 0.622-0.737, P < .001) with 71.7% sensitivity and 61.9% specificity, 16.1 for the neutrophil-to-lymphocyte ratio (NLR) (AUC = 0.634, 95% CI: 0.575-0.694, P < .001) with 65.5% sensitivity and 56.1% specificity, and 3872.5 x 10(9)L for the systemic inflammatory index (SII) (AUC = 0.566, 95% CI: 0.504-0.629, P = .038) with 60% sensitivity and 55.6% specificity. In the regression model, only NPR values above the cutoff were related to AKI (HR = 3.817, 95% CI: 1.782-8.177, P = .001). The NPR has more predictive value than the NLPR, NLR, and SII in developing AKI in severe COVID-19 patients in the ICU. NPR is a new helpful index that can help clinicians predict early AKI in critical COVID-19.Öğe Protective effect of gel form of gastric gavage applicated aloe vera on ischemia reperfusion injury in renal and lung tissue(C M B Assoc, 2017) Sahin, Hasan; Yener, Ali Umit; Karaboga, Ihsan; Sehitoglu, Muserref Hilal; Dogu, Tugba; Altinisik, Hatice Betul; Altinisik, UgurThe aloe vera plant has become increasingly popular in recent years. This study aimed to research the effect of aloe vera to prevent renal and lung tissue damage in an experimental ischemia-reperfusion (I/R) injury model. The study included 21 male Wistar Albino rats, which were categorized into control group, n = 7 (no procedures), Sham group n = 7 (I/R); and aloe vera therapy group, n = 7 (aloe vera and I/R). Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and malondialdehyde (MDA) were evaluated from lung and kidney tissues for biochemical investigations. As histopathological, hematoxylin and eosin and anti-iNOS were also examined. In biochemical investigations, SOD, CAT, and GPx levels of the Sham group were found to be lower compared with the other groups (P < 0.05). The aloe vera therapy group was not statistically different from control groups but significantly different compared with the Sham group. In the same way, the MDA levels of kidney and lung tissues were statistically significant in the aloe vera therapy group, compared to the Sham group. In the Sham group, the peribronchial and perialveolar edema were observed in lung parenchyma. Also, excess interstitial hemorrhage, leukocyte infiltration, and alveolar wall thickening were identified in ischemic groups. The histopathological changes were much lighter than in the aloe vera therapy group. In renal tissues, excess epithelial cell deterioration, tubular desqumination, and glomerular atrophy were observed in the Sham group. The histopathological changes were markedly reduced in the aloe vera therapy group. In the kidney and lung tissue, the level of iNOS activity in the Sham group was significantly higher than in the control and aloe vera therapy group. This study indicated that aloe vera is protective against oxidative damage formed by I/R in distant organs like the lungs and kidneys.Öğe The Effects of Sugammadex on Vitamin D Levels in Rabbits Under General Anesthesia(Galenos Yayincilik, 2019) Hunerel, Tugba; Altinisik, Hatice BetulObjective: Sugammadex is a widely used anesthetic agent for reversing of the non-depolarizing block. It reduces blood levels of steroid compounds by encapsulation. The aim of this study was to investigate the effect of sugammadex on the blood levels of vitamin D levels, which has a steroid structure. Materials and Methods: A total of 15 adult male New Zealand white rabbits weighing 2-2.5 kg were randomized into three groups according to decurarization: Group S [sugammadex (16 mg/kg), n=5], group N [neostigmine (0.05 mg/kg), n=5], group C (control group, n=5). Vitamin D levels from venous blood were measured at baseline, 20 minutes and 24 hours after general anesthesia. Results: Mean +/- SD vitamin D levels before anesthesia, 20 minutes and 24 hours after anesthesia were 4.42 +/- 0.60 ng/mL, 4.93 +/- 0.72 ng/mL, and 4.66 +/- 0.94 ng/mL for group S, 4.92 +/- 0.45 ng/mL, 5.02 +/- 0.41 ng/mL, and 5.41 +/- 0.56 ng/mL for group N, and 5.15 +/- 0.82 ng/ mL, 4.57 +/- 1.10 ng/mL, and 5.21 +/- 1.05 ng/mL for group C, respectively. There were no significant differences in the mean vitamin D levels between the groups at baseline, 20 minutes, and 24 hours. Conclusion: Contrary to expectations, it was found that sugammadex did not have a statistically significant effect on blood levels of vitamin D.
