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    Innovative i-PRF semisurgical method for gingival augmentation and root coverage in thin periodontal phenotypes: a preliminary study
    (Quintessence Publishing Co Inc, 2023) Alan, Ralf; Ercan, Esra; Firatli, Yigit; Firatli, Erhan; Tunali, Mustafa
    Objectives: The aim of the study was to evaluate the effect of in-jectable platelet-rich fibrin (i-PRF) on gingival thickness and gingi-val recession in individuals with thin periodontal phenotypes.Method and materials: In this prospective study, i-PRF was ap-plied via a semisurgical method to augment 53 tooth regions with thin periodontal phenotypes. In order to ensure that sufficient blood clot formed on the side of the gingiva facing the bone and that i-PRF reached the area, a minimal incision was made with the help of a scalpel in the apical region of the relevant region, and the periosteum was elevated with a microsurgical instrument. To en-sure sustained exposure to angiogenetic growth factors and en-hance the histoconductive properties, i-PRF injection was applied to the relevant areas in four sessions at 10-day intervals.Results: An increase in gingival thickness was achieved in 92.5% of the areas treated with i-PRF, and the desired gingival thickness (0.8 mm) was achieved in 44.9% of these areas. In addition, signif-icant reductions in the amount of recession were observed in 83.3%ofthe 12 gingival recession areas (P= .005). Moreover, com-plete coverage was achieved in 60% of these regions.Conclusion: With the new i-PRF sem isu rgica I method, it was shown that gingi-val thickness can be increased in tooth regions with thin gingiva, and that areas of gingival recession can be covered. Further com-prehensive studies are needed to fully understand the role of i-PRF in enhancing angiogenesis and the histoconductive properties of this fu lly autogenous blood concentrate. (Quintessence Int2023;54: 734-743; doi:10.3290/j.gi.b4328831)