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    Öğe
    Comparison of serum vitamin D levels between patients with deficit and non-deficit schizophrenia
    (Istanbul Universitesi, 2016) Akyol, Esra Soydaş; Aksoy, Nurkan; Şahin, Başak; Beyazyüz, Murat; Tekin, Ülker; Albayrak, Yakup
    Objective: Vitamin D deficiency has been proposed to play role in a series of psychiatric disorders including schizophrenia, however there have not been any knowledge regarding relationship between vitamin D deficiency and deficit syndrome schizophrenia (DS). In this study, we aimed to evaluate the relationship between vitamin D deficiency and deficit syndrome by comparing serum vitamin D levels of deficit schizophrenia patients and non-deficit schizophrenia (NDS) patients. Methods: Sixty-six patients who had the diagnosis of schizophrenia were included. Twenty-six patients comprised the DS group, while forty patients comprised the NDS group. The severity of illness was assessed with Scale of Assessment of Negative Symptoms (SANS), Scale of Assessment of Positive Symptoms (SAPS), and Brief Psychiatry Rating Scale (BPRS). Vitamin D concentrations of both groups were measured by an electrochemiluminescence method. Results: The groups were similar regarding age and gender (t=1.32; p=0.18 and X2=0.35; p=0.36, respectively). The mean SANS score and BPRS was higher in DS group compared to NDS group (t=- 3.86; p<0.001 and t=-2.13; p=0.03, respectively). The mean score of SAPS was found to be higher in NDS group compared with DS (t=-2.17; p=0.03). No statistically significant difference was observed between groups regarding serum 25(OH)D levels (t=1.36; p=0.17). Conclusion: The findings of the present study may suggest that vitamin D deficiency do not play a role in etiology of DS, although previous reports imply a relation between the vitamin D deficiency and schizophrenia. Further studies are needed to clarify the role of vitamin D in subgroups of schizophrenia. © 2016, Istanbul Universitesi. All rights reserved.
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    Öğe
    Investigation of pathological worry and metacognitive beliefs in patients with irritable bowel syndrome
    (Istanbul Universitesi, 2016) Akyol, Esra Soydaş; Şahin, Başak; Beyazyüz, Murat; Gökmen, Esra; Erbağ, Gökhan; Potas, Nihan
    Background: Irritable Bowel Syndrome is a functional gastrointestinal disease that affects approximately 20% of population. Irritable Bowel Syndrome is significantly associated with psychiatric symptoms. In the present study, we aimed to compare pathological worry and metacognitive beliefs between patients with Irritable Bowel Syndrome and healthy controls. Methods: Sixty-three patients with Irritable Bowel Syndrome and age-sex matched 55 healthy subjects were included to the study. Irritable Bowel Syndrome and healthy control group were compared in terms of pathological worry via Penn State Worry Questionnaire and metacognitive beliefs via Metacognition Questionnaire 30. Results: Patients with Irritable Bowel Syndrome scored significantly higher on Penn State Worry Questionnaire compared with healthy controls (t=2.69, p=0.008). The subscore of positive beliefs about worry was significantly higher in Irritable Bowel Syndrome group (t=2.16, p=0.03). The total score of Metacognition Questionnaire-30 and other subscores were found to be similar between groups. Conclusion: Our results suggest that the patients with Irritable Bowel Syndrome tend to have psychiatric disorders and patients may benefit from mindfulness therapies. Further and follow up studies are needed to highlight this issue. © 2016, Istanbul Universitesi. All rights reserved.