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    Accuracy and precision of cap thickness in small incision lenticule extraction
    (Dove Medical Press Ltd, 2013) Ozgurhan, Engin Bilge; Agca, Alper; Bozkurt, Ercument; Gencer, Baran; Celik, Ugur; Cankaya, Kadir IlKer; Demirok, Ahmet
    Aims: To report and compare the cap thickness predictability of small incision lenticule - extraction (SMILE) and flap thickness of femtosecond laser-assisted in situ keratomileusis (femto-LASIK). Settings and design: Beyoglu Eye Training and Research Hospital, Refractive Surgery Department, Istanbul, Turkey. Retrospective pilot study. Materials and methods: Medical records of patients who had SMILE in one eye and femtoLASIK in the other eye were reviewed. Visante corneal Optical Coherence Tomography (OCT) images at 1 week and 1month post-surgery were analyzed. Both cap and flap thickness at the temporal edge and the nasal edge were measured and compared to each other. Statistical analyses used: PAWS Statistics 18 and unpaired student t-test were used to compare the groups. Results: The study included 66 eyes of 33 patients (24.7 +/- 3.8 years, 20 females and 13 males). Mean flap thickness was 114.88 mu m +/- 4.96 mu m, and mean cap thickness was 114.63 mu m +/- 5.18 mu m. In group 1 (SMILE), cap thickness values were 115.84 mu m +/- 6.84 mu m, 114.75 mu m +/- 7.36 mu m, 113.66 mu m +/- 6.88 mu m, and 114.27 mu m +/- 6.90 mu m in measurement zones 1, 2, 3, and 4, respectively. In group 2 (FemtoLASIK), flap corneal thickness values were 115.96mmHg +/- 7.01mmHg, 114.72mmHg +/- 7.17mmHg, 113.54mmHg +/- 6.45mmHg, and 115.30mmHg +/- 6.64mmHg in measurement zones 1, 2, 3, and 4, respectively. In both groups, no statistically significant change within the measurement zones was observed. Conclusion: The predictability of cap thickness in SMILE surgery does not differ from the femto-LASIK flaps created using the same femtosecond laser platform.
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    Effect of Fluorometholone/Tetrahydrozoline Fixed Combination on Conjunctival Autograft Morphology after Primary Pterygium Excision
    (Hindawi Ltd, 2013) Ozgurhan, Engin Bilge; Kara, Necip; Bozkurt, Ercument; Gencer, Baran; Agca, Alper; Alkin, Zeynep; Demirok, Ahmet
    Purpose. To evaluate the effect of a fluorometholone/tetrahydrozoline fixed combination on conjunctival graft morphology after primary pterygium excision. Methods. The patients who underwent pterygium excision with conjunctival autograft transplantation were randomized into three groups based on postoperative medications as the fluorometholone/tetrahydrozoline group, fluorometholone group, and dexamethasone group. Conjunctival graft thickness was measured with anterior segment optical coherence tomography. The conjunctival graft hyperemia was evaluated using a high definition external camera. Results. The mean graft thickness was significantly lower in the fluorometholone/tetrahydrozoline group compared with fluorometholone and dexamethasone groups at 2 weeks (P = 0.002 and P = 0.012, resp.) and at 1 month after surgery (P = 0.003 and P = 0.013, resp.). The conjunctival hyperemia score was significantly lower in the fluorometholone/tetrahydrozoline group compared with fluorometholone and dexamethasone groups at 2 weeks (P = 0.000 and P = 0.000, resp.) and at 1 month (P = 0.039 and P = 0.040, resp.). The graft thickness and conjunctival hyperemia score were similar among the groups at 1 week and 3 months (P > 0.05). Conclusion. The findings of the present study revealed that treatment with the fluorometholone/tetrahydrozoline fixed combination may be helpful to decrease graft edema and to achieve better cosmetic appearance at 2 weeks and 1 month after pterygium excision.