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    A Study on Premenstrual Syndrome and Obsessive-Compulsive Symptoms Among University Students: A Cross-Sectional Study
    (Türkiye Klinikleri, 2025) Kaymaz, Nazan; Ertekin, Hülya; Kasap, Tolga; Şirin, Hande
    Objective: The present study aimed to investigate the potential correlation between Premenstrual syndrome (PMS) and obsessive-compulsive symptoms (OCS) among university students. Material and Methods: A cross-sectional study was conducted with female students from & Ccedil;anakkale Onsekiz Mart University, excluding those with neuropsychiatric or chronic physical illnesses. The data included sociodemographics (age, height, weight, economic status, menstrual cycle characteristics) and health behaviors (smoking, alcohol consumption). Premenstrual symptoms were evaluated with the PMS Scale (PMSS) and OCS with the Maudsley Obsessional-Compulsive Inventory (MOCIT). Participants were grouped based on PMSS scores indicating PMS presence, and correlation and regression analyses explored the relationship between PMS and OCS. Results: A total of 552 females aged 18-24 (mean age: 20.22 +/- 1.56) participated, with 74.2% (n=410) reporting PMS. PMS individuals had markedly higher total MOCI-T scores than non-PMS individuals (p <= 0.001). PMSS dimensions (except for abdominal bloating and appetite changes) showed associations with MOCI-T, with rumination exhibiting the strongest positive correlations (p <= 0.001). MOCI-T scores also correlated significantly with anxiety and depressive thoughts, with anxiety having a slightly stronger impact (B=0.315, (3=0.318, p <= 0.001 vs B=0.174, (3=0.194, p <= 0.001). Conclusion: The results indicate a significant link between PMS and OCS, emphasizing the intertwining of menstrual health and mental well-being in young females. Moreover, the correlations between PMS dimensions, OCS, and psychological factors like anxiety and depressive thoughts suggest a multifaceted relationship deserving a further study.
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    Examination of relationship factors between psychological resilience and social support in adolescent obesity
    (Elsevier, 2023) Uzun, Mehmet Erdem; Kara, Özlem; Şirin, Hande; Kaymaz, Nazan
    Purpose: Childhood obesity is one of the most severe public health problems, and psychiatric conditions have been associated with obesity. In this study, we aimed to investigate psychological resilience and possible related factors in adolescents with obesity. Method: The study included 90 adolescents with obesity and 100 healthy adolescents of similar age. Data were collected using a sociodemographic information form, the Child and Youth Resilience Measure-28 (CYRM-28), and the Multidimensional Scale of Perceived Social Support. Scale scores were compared by Pearson's correlation coefficient test with SPSS-23. Multiple linear regression was performed to describe the relationships between variables. Results: The adolescents participating in the study were similar in terms of age and gender. Psychological resilience and social support in the obesity group were lower than in the control group (p < 0.05). A negative relationship was found between body mass index (BMI) and resilience levels of adolescents with obesity, and a positive relationship was found between social support and resilience levels (p = 0.027 and p < 0.001, respectively). The perceived family and significant other social support subscale scores of adolescents in the obesity group were significantly lower than in the control group (p = 0.037 and p = 0.023, respectively). The most related variable with the CYRM-28 was the level of perceived social support: standardized β = 0.409; t(151) = 5.626; p < 0.001. Conclusion: A higher BMI has a negative effect on psychological resilience, and family support tends to be lower in these cases. New studies are needed to clarify whether this result is one of the causes of obesity or one of its consequences.
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    Pre-conception folic acid intake and attention deficit and hyperactivity disorder in children
    (Prusa Medical Publishing, 2023) Uzun, Mehmet Erdem; Kaymaz, Nazan; Aylanç, Hakan; Gökten, Emel Sarı; Şirin, Hande; Şehitoğlu, M.Hilal
    Objectives: Attention Deficit Hyperactivity Disorder (ADHD) is a common disorder in children. It is thought to occur due to the interaction of many genetic and environmental factors during early  development. Many studies have been conducted to investigate the etiology of ADHD. Some have investigated neurobiology, and others have investigated malnutrition and trace element deficiency. To investigate the effect of folic acid intake during the pre-conception period in terms of ADHD development. Methods: Five hundred and ninety-eight participants, 246 children with ADHD, and 352 healthy controls were enrolled. A questionnaire was completed, including socio-demographic information and the use of folic acid and other supplements such as a multivitamin, iron, and omega 3 during pregnancy. Data were examined to determine associations with ADHD. Mann-Whitney U tests for continuous variables, Pearson’s chi-square, and Fisher’s exact tests for categorical variables were used to compare groups. Results: The use of folic acid during pre-pregnancy among mothers who had a child with ADHD was 13% and this was 31% in the control group (p < 0.001). There was no statistically significant difference between the groups’ use of folic acid in pregnancy (p = 0.617). Other situations related to ADHD were advanced maternal age (p < 0.001 for both groups), abnormal double screening test results in pregnancy (27% vs. 5%, p < 0.001) and omega 3 use in pregnancy (p < 0.001). Conclusions: The use of folic acid before and during pregnancy is important for neurological development. However, there is little data on use before pregnancy in the literature. This study shows that folic acid taken before pregnancy may prevent ADHD in childhood. The present study recommends folic acid usage in planned pregnancy to prevent ADHD in the child.