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    Comparative Analysis of Filtering Surgery Approaches in Non-Granulomatous Uveitic Glaucoma: Combined or Standalone?
    (2025) Erdogan, Hakıka; Simsek, Tulay; Yildirim, Nilgun; Özer, Ahmet
    Objectives: To compare the 36-month outcomes of trabeculectomy alone versus combined phacotrabeculectomy in patients with non-granulomatous uveitic glaucoma (UG), focusing on intraocular pressure (IOP) control, surgical success, and postoperative intervention requirements. Methods: In this retrospective cohort study, 62 eyes with medically uncontrolled non-granulomatous UG were included. Patients were divided into two groups: Group 1 underwent combined phacoemulsification and trabeculectomy, while Group 2 underwent trabeculectomy alone. Preoperative and postoperative IOP measurements were evaluated over 36 months. Surgical success was defined as IOP between 5 and 21 mmHg, without additional glaucoma procedures or significant vision loss. Postoperative complications, medication requirements, and needling rates were also assessed. Results: The mean follow-up period was 36 months. The cumulative surgical success rate was higher in the combined group (88.2%) than in the trabeculectomy-alone group (71.1%), although the difference was not statistically significant (p > 0.05). Needling was significantly more frequent in Group 2 (p < 0.05), and more patients in Group 2 required antiglaucomatous medications postoperatively. No significant differences in complication rates or visual outcomes were observed between the groups. Conclusion: Both surgical approaches provide effective IOP control in uveitic glaucoma; however, combined surgery may result in fewer postoperative interventions and a trend toward improved 36-month surgical success. Careful patient selection and inflammation control remain crucial in optimizing outcomes.