Biyomühendislik: Recent submissions
Now showing items 1-20 of 59
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Ultrasensitive detection of interleukin 1α using 3-phosphonopropionic acid modified FTO surface as an effective platform for disposable biosensor fabrication
(Elsevier B.V., 2021)In this study, we utilized a carboxyalkylphosphonic acid covered fluorine doped tin oxide (FTO) as an electrode material for fabrication of Interleukin 1α (IL-1α) immunosensor. For this aim, anti-IL-1α antibodies were ... -
An impedimetric biosensor system based on disposable graphite paper electrodes: Detection of ST2 as a potential biomarker for cardiovascular disease in human serum
(Elsevier B.V., 2021)In present study, we developed a highly sensitive, electrochemical immunosensor based on fullerene C60-modified disposable graphite paper (GP) electrode for determination of Suppression of Tumorigenicity 2 (ST2) in human ... -
Advances in immunosensor technology
(Academic Press Inc., 2021)In recent years, advances in immunosensor device fabrication have significantly expanded the use of this technology in a broad range of applications including clinical diagnosis, food analysis, quality control, environmental ... -
Synthesis, characterization, and in vitro drug release properties of AuNPs/p(AETAC-co-VI)/Q nanocomposite hydrogels
(Springer Science and Business Media Deutschland GmbH, 2021)In this study, the cationic monomer [2-(acryloyloxy)ethyl]trimethylammonium chloride solution (AETAC) and vinyl imidazole (VI) were used with the free radical polymerization technique, which is a simple and rapid synthesis ... -
Decellularized spinal cord meninges extracellular matrix hydrogel that supports neurogenic differentiation and vascular structure formation
(John Wiley and Sons Ltd, 2021)Decellularization of extracellular matrices offers an alternative source of regenerative biomaterials that preserve biochemical structure and matrix components of native tissues. In this study, decellularized bovine spinal ... -
Ultrasensitive and Selective Impedimetric Determination of Prostate Specific Membrane Antigen Based on Di-Succinimide Functionalized Polythiophene Covered Cost-Effective Indium Tin Oxide
(John Wiley and Sons Inc, 2021)A new and ultrasensitive impedimetric biosensor fabricated by using conjugated di-succinimide substituted polythiophene (P(ThidiSuc)) polymer modified indium tin oxide electrode is developed for the first time to detect ... -
Electrochemical Immunosensor for Detection of CCR4 Cancer Biomarker in Human Serum: An Alternative Strategy for Modification of Disposable ITO Electrode
(Wiley-VCH Verlag, 2021)Herein, a new strategy for the fabrication of a sensitive immunosensor capable of determination of CC Chemokine receptor 4 (CCR4) in complex serum samples is developed through the polymer modification on the disposable ... -
Development and characterization of skin substitutes from electrospun polycaprolactone/silk fibroin
(SAGE Publications Ltd, 2024)Tissue-engineered skin substitutes have great potential to treat chronic wounds and high-degree burns. Existing solutions, such as Integra Dermal Template, are extensively used for skin defects. However, these templates ... -
Organic-inorganic biohybrid films from wool-keratin/jellyfish-collagen/silica/boron via sol-gel reactions for soft tissue engineering applications
(IOP Publishing, 2024)Therapeutic angiogenesis is pivotal in creating effective tissue-engineered constructs that deliver nutrients and oxygen to surrounding cells. Hence, biomaterials that promote angiogenesis can enhance the efficacy of various ... -
Phosphazene-based nanostructures modified with gold nanoparticles as drug and gene carrier materials with antibacterial and antifungal properties
(Taylor and Francis Ltd., 2024)In this study, monodisperse spherical particles were synthesized by using hexachlorocyclotriphosphazene (HCCP) and 1-(2-Aminoethyl) piperazine (AEP) by the polycondensation reaction. Then, the surfaces of the synthesized ... -
Ultrasensitive detection of NSE employing a novel electrochemical immunosensor based on a conjugated copolymer
(Royal Society of Chemistry, 2024)In the current study a simple and highly specific label-free impedimetric neuron specific enolase (NSE) immunosensor based on a copolymer matrix-coated disposable electrode was designed and tested. The copolymer matrix was ... -
Synthesis and characterization of poly(Maltodextrin) microgel from maltodextrin as drug delivery system
(Elsevier B.V., 2024)Microgels of maltodextrin (MDex) as poly(maltodextrin) (p(MDex)) were prepared by reverse-micelle crosslinking technique at various crosslinking ratios, 25, 50, and 100% based on the repeating unit of MDex using divinylsulfone ... -
Cell Staining Microgels Derived from a Natural Phenolic Dye: Hematoxylin Has Intriguing Biomedical Potential
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Hematoxylin (HT) as a natural phenolic dye compound is generally used together with eosin (E) dye as H&E in the histological staining of tissues. Here, we report for the first time the polymeric particle preparation from ... -
An innovative method for the detection of alpha synuclein, a potential biomarker of Parkinson's disease: quartz tuning fork-based mass sensitive immunosensor design
(Royal Society of Chemistry, 2024)An innovative biosensing fabrication strategy has been demonstrated for the first time using a quartz tuning fork (QTF) to develop a practical immunosensor for sensitive, selective and practical analysis of alpha synuclein ... -
A new immunosensing platform based on conjugated Poly(ThidEp-co-EDOT) copolymer for resistin detection, a new obesity biomarker
(Springer, 2024)The design of a novel electrochemical impedimetric biosensor for label-free analysis of resistin, a biomarker for obesity, is reported. For the fabrication of the immunosensor, a novel approach composed of electrochemical ... -
A Practical Approach for the Detection of Protein Tau with a Portable Potentiostat
(John Wiley and Sons Inc, 2023)Along with many factors, the change in protein tau isoforms, which has an obvious role in the function of microtubules, is an important biomarker of Alzheimer's disease. The aim of this study is to determine the protein ... -
Phosphazene-based nanostructures modified with gold nanoparticles as drug and gene carrier materials with antibacterial and antifungal properties
(Taylor and Francis Ltd., 2023)In this study, monodisperse spherical particles were synthesized by using hexachlorocyclotriphosphazene (HCCP) and 1-(2-Aminoethyl) piperazine (AEP) by the polycondensation reaction. Then, the surfaces of the synthesized ... -
Development of plant-based biopolymer coatings for 3D cell culture: boron-silica-enriched quince seed mucilage nanocomposites
(Royal Society of Chemistry, 2023)Spheroid formation with spontaneous aggregation has captured interest in most cell culture studies due to its easy set-up and more reliable results. However, the economic and technical costs of the advanced systems and ... -
A Review on Phyto-Therapeutic Approaches in Alzheimer's Disease
(MDPI, 2023)Neurodegenerative diseases occur due to progressive and sometimes irreversible loss of function and death of nerve cells. A great deal of effort is being made to understand the pathogenesis of neurodegenerative diseases. ... -
Physically Crosslinked Chondroitin Sulfate (CS)-Metal Ion (M: Fe(III), Gd(III), Zn(II), and Cu(II)) Particles for Versatile Applications and Their Biosafety
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Chondroitin sulfate (CS), a well-known glycosaminoglycan, was physically crosslinked with Fe(III), Gd(III), Zn(II), and Cu(II) ions to obtain CS-Fe(III), CS-Gd(III), CS-Zn(II), and CS-Cu(II) polymeric particles for ...
