Browsing by Author "Tatar, Gizem"

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Target-Driven Design of a Coumarinyl Chalcone Scaffold Based Novel EF2 Kinase Inhibitor Suppresses Breast Cancer Growth In Vivo

Cömert Önder, Ferah; Kahraman, Nermin; Bellur Atıcı, Esen; Çağır, Ali; Kandemir, Hakan; Tatar, Gizem; Ay, Mehmet (Amer Chemical Soc, 2021)

Eukaryotic elongation factor 2 kinase (eEF-2K) is an unusual alpha kinase involved in protein synthesis through phosphorylation of elongation factor 2 (EF2). eEF-2K is highly overexpressed in breast cancer, and its activity ...