Sen, FeyzaDemir, HakanAltun, Gülay DurmusÖzdemir, ElifÖzdemir, SemraTosun, Fevziye Canbaz2025-01-272025-01-2720202149-6447https://doi.org/10.4274/NTS.GALENOS.2020.0015https://hdl.handle.net/20.500.12428/13423Histologic confirmation of cardiac sarcoidosis (CS) is challenging. When taken into account of either the invasive nature or potential false negativity of the endomyocardial biopsy, imaging methods represent as a major alternative to establish a clinical diagnosis. Among the imaging methods, the use of fluorine-18-fluorodeoxyglucose (F-18 FDG) positron emission tomography/computed tomography (PET/CT) which detects active inflammation in CS is becoming widespread. Recently, F-18 FDG PET has been identified as one of the new diagnostic criteria in CS, by the Heart Rhythm Society. For diagnosis, a combination of both myocardial perfusion and inflammation findings should be interpreted visually and/or semiquantitatively. Yet, the precision of diagnostic accuracy has been limited by lack of an adequate reference standard. This procedure guideline presents current literature defining the role of F-18 FDG PET in the diagnosis and management of CS along with technical details and recommendations about imaging protocol and interpretation. © 2020 Nuclear Medicine Seminars. All Rights Reserved.trinfo:eu-repo/semantics/openAccessCardiac sarcoidosis; F-18 FDG PET/CT; InflammationArticle6221121910.4274/NTS.GALENOS.2020.00152-s2.0-85183311138Q4