Sehitoglu, Muserref HilalFarooqi, Ammad AhmadQureshi, Muhammad ZahidButt, GhazalaAras, Aliye2025-01-272025-01-2720141513-7368https://doi.org/10.7314/APJCP.2014.15.5.2379https://hdl.handle.net/20.500.12428/22496It is becoming progressively more understandable that phytochemicals derived from edible plants have shown potential in modelling their interactions with their target proteins. Rapidly accumulating in-vitro and in- vivo evidence indicates that anthocyanins have anticancer activity in rodent models of cancer. More intriguingly, evaluation of bilberry anthocyanins as chemopreventive agents in twenty-five colorectal cancer patients has opened new window of opportunity in translating the findings from laboratory to clinic. Confluence of information suggests that anthocyanins treated cancer cells reveal up-regulation of tumor suppressor genes. There is a successive increase in the research-work in nutrigenomics and evidence has started to shed light on intracellular-signaling cascades as common molecular targets for anthocyanins. In this review we bring to limelight how anthocyanins induced apoptosis in cancer cells via activation of extrinsic and intrinsic pathways.eninfo:eu-repo/semantics/openAccessApoptosisanthocyaninssignalingcancerEditorial1552379238110.7314/APJCP.2014.15.5.2379Q3WOS:0003356512000832-s2.0-8489906508824716988Q3