Do?u, Tu?baŞahin, HasanErbaş, MesutŞimşek, TuncerToman, HüseyinAltinişik, Hatice BetülKiraz, Hasan Ali2025-01-272025-01-2720151300-0578https://hdl.handle.net/20.500.12428/13893Wilson's disease (WD) is an autosomal recessive disorder characterized by mutations in the ATP7B gene, which causes the disorder of copper excretion into bile. In this study we aimed to discuss our anesthesia experience in a Wilson's disease patient who underwent emergency surgical procedures for appendicitis. A 42-year-old male WD patient suffering the disease for 6 years with a diagnosis of cardiomyopathy and asthma, was planned an emergency surgery for appendicitis. The patient's neurological examination was normal. General anesthesia was preffered and for induction 2 mg kg-1 propofol, 1 ?g kg-1 fentanyl, and 0.5 mg kg-1 rocuronium was intravenously administered. Anesthesia was maintained with 50% oxygen and 50% air and 2% sevoflurane. The patient was extubated uneventfully, subsequently postoperative choreiform movements occurred. During the postoperative follow-up, the patient's choreiform movements were observed to disappear and declined by between 3-6 hours. We did not observe a delay in the patient's anesthesia recovery. Consequently, we think general anesthesia can be uneventually applied in Wilson's disease patients by using least toxic agents to the liver, protective measures and with an attentive follow-up in the perioperative and postoperative periods.trinfo:eu-repo/semantics/closedAccessAnesthesia; Wilson diseaseArticle2331821842-s2.0-84941614741Q4