Ayduran, SemraKilbas, GulsahTigrak, Saadet NilayYuksel, SelcukComut, ErdemTurkucar, Serkan2025-01-272025-01-2720250028-2715https://doi.org/10.31729/jnma.8874https://hdl.handle.net/20.500.12428/13214Panniculitis is a rare clinical finding in dermatomyositis. There are few reported cases in the medical literature. In this report, we describe a 17-year-old male patient with anti-MDA5 positive hypomyopathic dermatomyositis who, eight months after diagnosis, presented with indurated nodules on the right forearm and right thigh despite methotrexate and monthly intravenous immunoglobulin treatment. A skin biopsy revealed lobular panniculitis with lymphocytic infiltrate. His lesions were successfully controlled with hydroxychloroquine and azathioprine. This article presents a case regarding the rarity of panniculitis in juvenile dermatomyositis and its treatment strategy. © 2025, Nepal Medical Association. All rights reserved.eninfo:eu-repo/semantics/closedAccessanti MDA-5; dermatomyositis; panniculitisArticle63281616410.31729/jnma.88742-s2.0-85214870980Q3