Bek, SibelBatman, AdnanEren, NecmiTuğan, Büşra YılmazBakırdöğen, Serkan2025-01-272025-01-2720212147-0758https://search.trdizin.gov.tr/tr/yayin/detay/487644https://hdl.handle.net/20.500.12428/18572INTRODUCTION: Optical coherence tomography (OCT) is anon-invasive ocular imaging technique widely used nowadays.There are limited studies focusing on the OCT findings in PDpatients. Our aim is to compare retinal changes of peritonealdialysis (PD) patients with healthy control group by using OCT and investigate the effects of age, gender and duration of PDon these parameters. METHODS: In this cross-sectional study right and left eyes of32 patients and twenty right and left eyes of ten healthycontrols were included. Detailed ophthalmologicalexaminations with central macular thickness (CMT),peripapillary retinal nerve fiber layer (RNFL) thickness, andchoroidal thickness (using EDI-OCT) were measured. Macularthickness was measured at five different areas:central,superior, temporal, inferior and nasal. Theperipapillary RNFL thickness was analysed in six differentareas: temporal, inferotemporal, inferonasal, nasal,superonasal and superotemporal. RESULTS: Sixty-four eyes of 32 patients (18 males, 14females; aged 20 to 60 years, mean 48.67±12.25 years) with amean duration of PD of 46.80 months were included. Therewas a significant difference of macular thickness in the central,temporal, nasal, inferior and superior quadrants betweencontrols and PD patients (p < 0.05). Vitamin D3supplementation was linked to decreased macular thickness incentral, temporal, superior, nasal and inferior quadrants(p<0.05). There was a positive correlation between macularthickness in central and temporal quadrants with residualrenal function (p=0.006, p=0.019). DISCUSSION AND CONCLUSION: OCT revealed asignificant reduction of macular thickness in all quadrants inPD patients.eninfo:eu-repo/semantics/openAccessGenel ve Dahili TıpGöz Hastalıklarıİstatistik ve OlasılıkArticle101147153487644