Deniz, YeşimIşıktaş Acar, EzgiÇetin Genç, Çiğdem2023-08-212023-08-212023Deniz, Y., Acar, E. I., & Genç, Ç. Ç. (2023). Effects of direct therapeutic radiation on pulpal surface of root dentin: an in vitro study. Radiation and Environmental Biophysics, 62(2), 261–268. https://doi.org/10.1007/s00411-023-01020-90301-634X1432-2099https://doi.org/10.1007/s00411-023-01020-9https://hdl.handle.net/20.500.12428/4496The aims of the study were to analyze the effects of therapeutic radiation on human root dentin samples from the aspect of possible alterations in crystallinity, micro-morphology, and composition. Fifty-six root dentin specimens were divided into seven groups (0, 10, 20, 30, 40, 50, and 60 Gy). Scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD) analyses were performed on pulpal surfaces of root dentin after being irradiated by 6MV photon energy. Mineral compositions, Ca/P, P/N, Ca/N ratios, and hydroxyapatite pikes were calculated. Some deuteriations on the dentin surface were observed in SEM images after 30 Gy and subsequent doses. One-way ANOVA revealed that there was no significant alteration in weight percentages of C, O, Mg, Ca, P, and N between groups. Radiation did not influence stoichiometric Ca/P, Ca/N, and P/N molar ratios. XRD analysis did not show a remarkable decline in hydroxyapatite pikes by the increasing doses. Radiotherapy changes the micromorphology of circumpulpal dentin but does not affect elemental composition and crystallinity.eninfo:eu-repo/semantics/closedAccessHead and neck neoplasmsMouth neoplasmsRadiobiologyRadiotherapyToothArticle62226126810.1007/s00411-023-01020-9Q4WOS:0009529406000012-s2.0-8515017057936933029