Basaran, IhsanOral, Ayhan2025-01-272025-01-2720180091-40371563-535Xhttps://doi.org/10.1080/00914037.2017.1417287https://hdl.handle.net/20.500.12428/27278Gelatin-polycaprolactone hybrid materials are being used in medicinal applications such as drug delivery, tissue engineering applications nowadays. In this study, gelatin-polycaprolactone graft copolymer was synthesized through ring-opening polymerization process instead of conventional grafting methods using potentially cytotoxic crosslinkers, or applying plasma, aminolysis reactions. Gelatin nanofiber (GNF) was produced by electrospinning process before immobilization of poly(epsilon-caprolactone). Ring-opening polymerization of epsilon-caprolactone was successfully initiated on the surface of GNF using tin(IV) isopropoxide and gelatin (primary amine functional groups) as an initiator and a coinitiator, respectively. The growing of polymer chains on GNF was indicated by both scanning electron microscope and energy-dispersive X-ray spectroscopy. Chemical structure was characterized through infrared spectrum, thermal behaviors and the material composition was analyzed with thermogravimetric analysis, wettability and hydrophilicity were determined by water contact angle measurements. [GRAPHICS] .eninfo:eu-repo/semantics/closedAccessElectrospinninggraft copolymersnanofiberpolyestersring-opening polymerizationArticle67181051105810.1080/00914037.2017.1417287Q2WOS:0004427554000012-s2.0-85040995124Q1