Tan, BurcuBaycan, Fatma2025-01-272025-01-2720222365-6549https://doi.org/10.1002/slct.202103437https://hdl.handle.net/20.500.12428/25258N,N '-bis(2-hexyl)-2,6-(3,4 ethylenedioxythiophene)-1,4,5,8-naphthalenimide (ENDI) monomer was electropolymerized on pencil graphite electrode (PGE) and used as a biosensor for glucose immobilization for the first time. After electropolymerization of ENDI monomer on PGE (AuNPs/PENDI/PGE), the intensity of the current signal was improved by using gold nanoparticles (AuNPs). The immobilization of the glucose oxidase (GOx) enzyme was carried out by using the cross-linking reagent glutaraldehyde (GA) due to the strong pi-pi* interaction of the poly- N,N '-bis(2-hexyl)-2,6-(3,4 ethylenedioxythiophene)-1,4,5,8-naphthalenimide (PENDI) polymer. GOx/AuNPs/PENDI/PGE designed biosensor, was characterized by a wide linear glucose determination range between 0.0009-0.33 mM with a limit of detection of 0.0407 mM and a sensitivity of 0.172 mu A/mMcm(2). Herein we have shown that GOx/AuNPs/PENDI/PGE biosensor effectively provides the enzyme immobilization and very effective for glucose determination in commercial samples.eninfo:eu-repo/semantics/closedAccessglucose biosensorpencil graphite electrode graphiteelectropolymerizationnaphthalenedimide-3,4-Ethylenedioxythiophenegold nanoparticlesArticle7210.1002/slct.202103437Q3WOS:0007539700000252-s2.0-85123731803Q3