Bekler, AdemErbag, GokhanSen, HacerGazi, EmineOzcan, Sedat2025-01-272025-01-2720151682-024Xhttps://doi.org/10.12669/pjms.311.5967https://hdl.handle.net/20.500.12428/20764Objective: We aimed to study the predictive value of the neutrophil-lymphocyte ratio (NLR) for left ventricular systolic dysfunction (LVSD) in patients with non ST-elevated acute coronary syndrome (NST-ACS). Methods: A total of 405 patients (mean age 62 years and 75% male) with NST-ACS were included in the study. The study population was divided into tertiles based on admission NLR values. The low, medium and high tertiles defined as NLR <= 1.81 (n=135), 1.81<=.3.2 (n=135) and NLR>3.2 (n=135), respectively. Results: The patients in the high NLR group were older (p<0.001), have higher rate of diabetes mellitus (p=0.028) and non-ST elevated myocardial infarction (NSTEMI) (p<0.001) and have lower left ventricular ejection fraction (LVEF) (p<0.001). Baseline WBC (p=0.02) and neutrophil (p<0.001) levels and NLR (p<0.001) were significantly higher, baseline hemoglobin (p=0.044), hematocrit (p=0.019) and lymphocyte (p<0.001) levels were significantly lower in the high NLR group. NLR was negatively correlated with LVEF in correlation analysis. An NLR >3.2 and age >= 70 were found to be an independent predictor of systolic dysfunction in multivariate analyses. Conclusion: An NLR >3.2 is a useful predictor for LVSD in patients with NST-ACS. The practice of using an NLR count on admission may be useful for identifying high-risk patients and their associated treatment methods.eninfo:eu-repo/semantics/openAccessAcute coronary syndromeEjection fractionMyocardial infarctionNeutrophil-lymphocyte ratioSystolic dysfunctionArticle31115916310.12669/pjms.311.5967Q4WOS:0003499365000322-s2.0-8491980805425878635Q1