Sılan, FatmaYalcintepe, SinemUysal, DigdemUrfali, MineUludağ, AhmetCosar, EmineGungor, Ayse Nur Cakir2025-01-272025-01-2720141529-9120https://hdl.handle.net/20.500.12428/14190Numerical and/or structural chromosomal abnormalities may be a reason of high infertility rates and recurrent pregnancy losses (RPLs) in humans. Karyotype and karyogram profiles of patients with RPLs are presented in current results. A total of 722 patients; 161(44.5%) infertile and 200(55.5%) RPL couples were included in the study. Karyotype and structural chromosome analyses of both patient groups in Canakkale population were made between May 2011-December 2013, using peripheral lymphocyte cell culture and GTG banding technique. High frequency of chromosomal abnormalities(%7.45) were detected in 24 patients of the infertility group(n:322). 10 patients(42%) of this group(n:24) had numerical and 14 patients(58%) had balanced structural choromosomal abnormalities. A novel choromosomal insertion was found in an infertile male, one of the 22th choromosome was totally inserted in 9th choromosome [ins(9;22)(9pter-q12eninfo:eu-repo/semantics/closedAccessChromosome; Cytogenetics; Insertion; Inversion; TranslocationHigh frequency of chromosomal anomalies and a novel chromosomal insertion associated with infertility and recurrent miscarriages (reproductive failure) in West TurkeyArticle1611391482-s2.0-84920641639N/A