Aschenbach, JRAtasoglu, CBorau, TGäbel, G2025-01-272025-01-2720041230-1388https://doi.org/10.22358/jafs/73882/2004https://hdl.handle.net/20.500.12428/2296410th International Symposium on Ruminant Pysiology -- AUG 30-SEP 04, 2004 -- Copenhagen, DENMARKThis study aimed to elucidate whether sheep can increase ruminal glucose absorption acutely to counteract lactic acid formation after a concentrate meal. Pre-incubation of Ussing-chambered ruminal epithelia with D-glucose (10 mM) on both sides for 180 min increased the apical uptake of 0.2 mM C-14-D-glucose. An equivalent effect was seen after serosal but not mucosal pre-incubation with D-glucose for only 10 min. However, a 30-s serosal pre-incubation with D-glucose did not stimulate D-glucose uptake. Stimulation of uptake by serosal D-glucose was not seen after phlorizin treatment. Thus, ruminal glucose absorption via SGLT-1 can be up-regulated acutely via a basolateral glucosensor.eninfo:eu-repo/semantics/openAccessglucosensorrumensheepsodium glucose-linked transportruminal lactic acidosisConference Object1326126410.22358/jafs/73882/2004Q3WOS:0002236105000622-s2.0-6944228072Q2